Patents by Inventor Asato Kojima

Asato Kojima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • West Nile virus prM-E signal peptide facilitating the efficient assembly, maturation, and release of virus-like particles (VLPs)
    Patent number: 8795687
    Abstract: The present invention provides virus-like particles (VLP) highly secreting or producing signal peptide obtained by altering a signal sequence derived from West Nile virus (WNV), the signal peptide, a WNV VLP secretion expression vector containing a nucleic acid encoding prM protein and E protein, a WNP VLP highly secreting or producing animal cell line harboring the vector, a WNV vaccine containing WNV VLP obtained by the cell line as an active ingredient, and a WNV DNA vaccine containing the VLP secretion expression vector as an active ingredient.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: August 5, 2014
    Assignees: Japan as Represented by the Director-General of National Institute of Infections Diseases, The Research Foundation for Microbial Diseases of Osaka University
    Inventors: Asato Kojima, Hidehiro Takahashi, Toyokazu Ishikawa
  • WEST NILE VIRUS VACCINE, AND METHOD FOR PRODUCTION THEREOF
    Publication number: 20140065180
    Abstract: The invention provides virus-like particles (VLP) highly secreting or producing signal peptide obtained by altering a signal sequence derived from West Nile virus (WNV), the signal peptide, a WNV VLP secretion expression vector containing a nucleic acid encoding prM protein and E protein, a WNP VLP highly secreting or producing animal cell line harboring the vector, a WNV vaccine containing WNV VLP obtained by the cell line as an active ingredient, and a WNV DNA vaccine containing the VLP secretion expression vector as an active ingredient.
    Type: Application
    Filed: November 4, 2013
    Publication date: March 6, 2014
    Applicants: The Research Foundation for Microbial Diseases of Osaka University, Japan as Represented by the Director-General of National Inst. of Infectious Diseases
    Inventors: Asato KOJIMA, Hidehiro TAKAHASHI, Toyokazu ISHIKAWA
  • WEST NILE VIRUS VACCINE, AND METHOD FOR PRODUCTION THEREOF
    Publication number: 20100247559
    Abstract: The present invention provides virus-like particles (VLP) highly secreting or producing signal peptide obtained by altering a signal sequence derived from West Nile virus (WNV), the signal peptide, a WNV VLP secretion expression vector containing a nucleic acid encoding prM protein and E protein, a WNP VLP highly secreting or producing animal cell line harboring the vector, a WNV vaccine containing WNV VLP obtained by the cell line as an active ingredient, and a WNV DNA vaccine containing the VLP secretion expression vector as an active ingredient.
    Type: Application
    Filed: November 7, 2008
    Publication date: September 30, 2010
    Applicants: Japan as Represented by the Director-General of National Institute of Infectious Diseases, The Research Foundation for Microbial Diseases of Osaka University
    Inventors: Asato Kojima, Hidehiro Takahashi, Toyokazu Ishikawa
  • Recombinant vaccinia virus expressing E-protein of Japanese encephalitis virus
    Patent number: 5021347
    Abstract: There is provided a recombinant vaccinia virus having inserted cDNA coding for E-protein of Japanese encephalitis virus into a genome region non-essential to growth of a vaccinia virus, in the form of capable expression. The recombinant vaccinia virus is useful as a live vaccine.
    Type: Grant
    Filed: September 15, 1988
    Date of Patent: June 4, 1991
    Assignees: Nippon Zeon Co., Ltd., Director-General of National Institute of Health, Tokyo Metropolitan Institute for Neuroscience
    Inventors: Kotaro Yasui, Asato Kojima, Atsushi Yasuda, Takanori Sato