Abstract: Certain embodiments herein disclose a cannula assembly. The cannula assembly comprises a cannula, having a proximal end and a distal end. The cannula comprises a head at the proximal end, the head having one or more wings. The cannula also comprises a hollow rod extending from the head to the distal end. The cannula assembly also comprises a hub couplable to the head and having a housing with an inner wall. The inner wall comprises an undercut, and one or more distal ends of the corresponding one or more wings are configured to fit into the undercut and couple the hub to the head upon insertion of the head into the hub.

Abstract: A computer-implemented method of performing motion compensation on a temporal sequence of digital subtraction angiography, DSA, images includes: inputting (S120) a temporal sequence of DSA images (110) into a neural network (120) trained to predict, from the inputted temporal sequence (110), a composite motion-compensated DSA image (130) representing the inputted temporal sequence (110) and which includes compensation for motion of the vasculature between successive contrast-enhanced images in the temporal sequence, and which also includes compensation for motion of the vasculature between acquisition of contrast-enhanced images in the temporal sequence and acquisition of the mask image; and outputting (S130) the predicted composite motion-compensated DSA image (130).

Abstract: A trocar-cannula insertion tool for ophthalmic procedures may include a cap with a body having a proximal end and a distal end opposite the proximal end. A marking element extends in a distal direction from the distal end of the body and includes at least one marking tip for forming one or more indentations on a patient's eye during an ophthalmic procedure. A manipulation element extends from the body in a direction different from the marking element and includes at least one manipulation tip for gripping a tissue of the patient's eye during the ophthalmic procedure. The cap may further include at least one window for exposing a photoluminescent cannula of the trocar-cannula insertion tool to light, enabling the cannula to absorb photons prior to insertion thereof.

Abstract: Embodiments disclosed herein relate to an infusion cannula for infusion/venting of fluids to/from the eye to control intraocular pressure. The infusion cannula includes a tubular body with a tubular inlet located at a proximal end of the tubular body and a tubular outlet located at a distal end of the tubular body. The tubular outlet is aligned with a first longitudinal axis and configured to extend through a septum of a valved cannula hub. The infusion cannula includes a retention piece extending from or coupled to the tubular body. The retention piece has an annular body surrounding the tubular body at the distal end of the tubular body and configured to be coupled to the valved cannula hub. An inner surface of the annular body has a profile configured to form a snap fit with an overhang formed along an outer surface of the valved cannula hub.

Abstract: A platform configured to secure a service loop of tubing from a fixed position surgical device. The platform allows for avoidance of taping and re-taping of service loops. Additionally, the platform provides stability to the surgical device so as to avoid unintentional changing of position or orientation of the device. This is of particular benefit for an infusion port during eye surgery and other similar devices where orientation of the installed device aids device performance.

Abstract: Embodiments disclosed herein provide devices, systems, and methods for instrument exchanges during ophthalmic surgery. More particularly, the present disclosure relates to valved cannula assemblies and methods of use thereof. A valved cannula assembly includes a cannula having a head at a proximal end of the cannula and a hollow rod extending from the head to a distal end of the cannula. The valved cannula assembly includes a valved hub coupled to the head and including a septum having two or more curved flaps configured to provide an opening for an instrument.

Abstract: The present disclosure relates to trocar-cannula insertion tools for ophthalmic procedures. In certain embodiments, a cap for a trocar-cannula insertion tool includes a body having a proximal end and a distal end opposite the proximal end. A marking element extends in a distal direction from the distal end of the body and includes at least one marking tip for forming one or more indentations on a patient's eye during an ophthalmic procedure. A manipulation element extends from the body in a direction different from the marking element and includes at least one manipulation tip for gripping a tissue of the patient's eye during the ophthalmic procedure. In certain embodiments, the cap further includes at least one window for exposing a photoluminescent cannula of the trocar-cannula insertion tool to light, enabling the cannula to absorb photons prior to insertion thereof.

Abstract: Certain aspects of the present disclosure generally relate to ophthalmic surgery, and more particularly, to methods and apparatuses for controlling intraocular pressure (IOP) and administering ocular tamponades during or after ophthalmic surgery. An exemplary apparatus generally includes a proximal segment having a first inner diameter (ID), a first proximal end, and a first distal end. The apparatus further includes a distal segment having a second ID smaller than the first ID, a second proximal end, and a second distal end configured to be disposed inside a hub or a cannula transition of a valved cannula comprising the hub, a shaft, and the cannula transition between the hub and the shaft.

Abstract: Embodiments disclosed herein relate to an infusion cannula for infusion/venting of fluids to/from the eye to control intraocular pressure. The infusion cannula includes a tubular body with a tubular inlet located at a proximal end of the tubular body and a tubular outlet located at a distal end of the tubular body. The tubular outlet is aligned with a first longitudinal axis and configured to extend through a septum of a valved cannula hub. The infusion cannula includes a retention piece extending from or coupled to the tubular body. The retention piece has an annular body surrounding the tubular body at the distal end of the tubular body and configured to be coupled to the valved cannula hub. An inner surface of the annular body has a profile configured to form a snap fit with an overhang formed along an outer surface of the valved cannula hub.

Abstract: A method and system for disinfecting or sanitizing with aqueous ozone sprayed at high pressures. The method includes producing aqueous ozone having an ozone concentration of about 1 ppm to about 4 ppm. The method includes, delivering the aqueous ozone to a sprayer at a pressure of about 200 psi to about 600 psi. The method includes spraying the pressurized aqueous ozone at a surface to reduce microbe populations on the surface.

Abstract: A cooling system for a microchip or other component is described, including, in one embodiment: (1) a cold plate assembly positioned adjacent (e.g., in contact with) the component to be cooled; (2) at least one heat exchanger; (3) a fan for directing gas adjacent (e.g., through) a portion of the heat exchanger; and (4) a pump for circulating cooling fluid through a closed circuit including the cold plate and heat exchanger. The cold plate may include guide fins that define macrochannels and microchannels that serve as conduits for the cooling fluid. The fins and channels in one embodiment are shaped to substantially match the heat map profile of the chip or component to be cooled. The heat exchanger in one embodiment includes a reservoir in its base which may cooperate with a recess or channel in a support plate to form an additional cooling fluid flow passage.