Abstract: Disclosed herein are methods of diagnosing and treating MYC-driven cancers by detecting a PVT1 splice variant in a biological sample from a subject.

Abstract: There is described herein a method for detecting anomalies in an infrastructure, the method comprising: providing a computationally-intelligent analysis model to model a behaviour of at least one detection instrument in said infrastructure; inputting control instrument data into said analysis model, said control instrument data being provided by control instruments in said infrastructure; outputting an estimated behaviour for said at least one detection instrument from said analysis model; comparing actual data from said at least one detection instrument to said estimated behaviour and generating a set of residuals representing a difference between said actual data and said estimated behaviour; and identifying anomalies when said residuals exceed a predetermined threshold.

Abstract: There is described herein a method for detecting anomalies in an infrastructure, the method comprising: providing a computationally-intelligent analysis model to model a behaviour of at least one detection instrument in said infrastructure; inputting control instrument data into said analysis model, said control instrument data being provided by control instruments in said infrastructure; outputting an estimated behaviour for said at least one detection instrument from said analysis model; comparing actual data from said at least one detection instrument to said estimated behaviour and generating a set of residuals representing a difference between said actual data and said estimated behaviour; and identifying anomalies when said residuals exceed a predetermined threshold.

Abstract: A service provider is enabled to easily create and distribute data network services over a wide area data network such as the Internet. Powerful distributed computing technology and popular standards like Domain Name Service (DNS) and Extensible Markup Language (XML) may be leveraged to provide a scalable and secure service infrastructure. A directory service utility maintains a registry of service providers of data network services. In response to receiving a query for a particular service, the directory service utility identifies a provider of the particular service to the network connected device. The network connected device may then contact the service provider directly and receive an application (i.e., an executable file) for accessing the particular data network service. Distributed computing features are used to reduce the need for widespread distribution of additional protocols when new services are created.