Patents by Inventor Ashvani Kumar Singh

Ashvani Kumar Singh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulators of ATP-binding cassette transporters
    Patent number: 8822451
    Abstract: 4-amido-pyrimidine compounds, derivatives and compositions thereof, and synthetic methods described herein are useful for modulating ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
    Type: Grant
    Filed: May 22, 2006
    Date of Patent: September 2, 2014
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Sara S. Hadida Ruah, Anna R. Hazlewood, Peter D. J. Grootenhuis, Ashvani Kumar Singh, Thomas Cleveland, Frederick F. Van-Goor
  • MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS
    Publication number: 20120184583
    Abstract: The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
    Type: Application
    Filed: April 4, 2011
    Publication date: July 19, 2012
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Frederick F. Van Goor, Sara Sabina Hadida-Ruah, Ashvani Kumar Singh, Eric R. Olson, Lewis Ray Makings, Jesus E. Gonzalez, III, James Arvid Rader, Fred Chambers, III, Mark Thomas Miller, Peter Diederik Jan Grootenhuis, Yahua Liu
  • Modulators of ATP-Binding Cassette Transporters
    Publication number: 20100144798
    Abstract: The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
    Type: Application
    Filed: August 20, 2009
    Publication date: June 10, 2010
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Frederick F. VanGoor, Sara Sabina Hadida Ruah, Ashvani Kumar Singh, Eric R. Olson, Lewis Ray Makings, Jesus E. Gonzalez, III, James Arvid Rader, Fred Chambers, III, Mark Thomas Miller, Peter Diederik Jan Grootenhuis, Yahua Liu