Abstract: Described is a method of diagnosis or prognosis of preeclampsia in a pregnant subject, comprising providing a sample from a pregnant subject and measuring the ratio between the amount of (a) one or both of sFlt-1 and PlGF, and (b) one or both of a breakdown product of heme and a breakdown product of arginine, in the sample. Also described are assay kits and a computer adapted for use in the method. Also described is a method of treating preeclampsia, comprising administering a pharmaceutically effective amount of L-arginine and/or citrulline and an inhibitor of arginase or pharmaceutically acceptable salts thereof. Also described is a method of treating cancer, comprising treating a subject with a therapeutically effective amount of an anti-VEGF compound, L-arginine and an arginase inhibitor.

Abstract: A tool may identify and revert changes that caused network hardware components or hardware servers to malfunction. The tool builds and maintains a graph that represents the hardware components and servers in the system and their dependencies. When a change is made to the system, links and weights in the graph are adjusted to account for the changes. When a component or server is reported as malfunctioning, the tool traverses the graph to locate the changes that are the most likely root causes of the malfunction. The tool may then revert the change to resolve the malfunction.

Abstract: A tool may identify and revert changes that caused network hardware components or hardware servers to malfunction. The tool builds and maintains a graph that represents the hardware components and servers in the system and their dependencies. When a change is made to the system, links and weights in the graph are adjusted to account for the changes. When a component or server is reported as malfunctioning, the tool traverses the graph to locate the changes that are the most likely root causes of the malfunction. The tool may then revert the change to resolve the malfunction.

Abstract: A tool may identify and revert changes that caused network hardware components or hardware servers to malfunction. The tool builds and maintains a graph that represents the hardware components and servers in the system and their dependencies. When a change is made to the system, links and weights in the graph are adjusted to account for the changes. When a component or server is reported as malfunctioning, the tool traverses the graph to locate the changes that are the most likely root causes of the malfunction. The tool may then revert the change to resolve the malfunction.

Abstract: A stage, suitable for use in an analog to digital converter or a digital to analog converter, can have a plurality of slices that can be operated together to form a composite output. The stage can have reduced thermal noise, while each slice on its own has sufficiently small capacitance to respond quickly to changes in digital codes applied to the slice. This feature allows a fast conversion to be achieved without loss of noise performance.

Abstract: An electronic medical record system monitors physician orders for diagnostic imaging and uses natural language processing to generate a field for characterizing the clinical significance of the image identified by the radiologist. This natural redundancy of evaluation of the efficacy of the imaging is used to generate reports allowing physicians to compare their effective use of diagnostic imaging against their peers.

Abstract: An electronic circuit comprises multiple analog-to-digital converter (ADC) circuits and control logic circuitry. The control logic circuitry advances the multiple ADC circuits through multiple time-interleaved conversions that include time-interleaved acquisition phases, conversion phases, and tracking phases. An acquisition phase of a first ADC circuit samples the analog signal, a conversion phase of the first ADC circuit converts the sampled analog signal to a digital value, and the control logic circuitry is configured to update the first ADC circuit with most recent A/D conversion information by a different ADC circuit during a tracking phase of the first ADC circuit before the acquisition phase of the first ADC circuit.

Abstract: A stage, suitable for use in an analog to digital converter or a digital to analog converter where the stage comprises a plurality of slices that can be operated together to form a composite output, can have reduced thermal noise, whilst each slice on its own has sufficiently small capacitance to respond quickly to changes in digital codes applied to the slice. This allows a fast conversion to be achieved without loss of noise performance.

Abstract: A stage, suitable for use in an analog to digital converter or a digital to analog converter, can have a plurality of slices that can be operated together to form a composite output. The stage can have reduced thermal noise, while each slice on its own has sufficiently small capacitance to respond quickly to changes in digital codes applied to the slice. This feature allows a fast conversion to be achieved without loss of noise performance.

Abstract: A stage, suitable for use in and analog to digital converter or a digital to analog converter, comprises a plurality of slices. The slices can be operated together to form a composite output having reduced thermal noise, while each slice on its own has sufficiently small capacitance to respond quickly to changes in digital codes applied to the slice. This allows a fast conversion to be achieved without loss of noise performance. The slices can be sub-divided to reduce scaling mismatch between the most significant bit and the least significant bit. A shuffling scheme is implemented that allows shuffling to occur between the sub-sections of the slices without needing to implement a massively complex shuffler.

Abstract: A dither is an uncorrelated signal, usually pseudo-random noise injected into the input of an ADC such that a given input value of the wanted signal becomes spread over a plurality of codes. This reduces the effect of DNL and also smooths the integral non-linearity (INL) response of the ADC. The advantages of introducing dither could be obtained without having to perturb the signal input to the ADC. This avoids the introduction of additional components in the ADC. The dither can be applied to the components used to form a residue of the ADC stage within a pipelined converter. For example, a dither can be applied solely to a DAC part or different dithers can be applied to a ADC and DAC parts respectively. This allows greater flexibility of linearization of the ADC response and the formation of an analog residue by the DAC.

Abstract: Disclosed herein is a secure messaging engagement hub for structuring of unstructured electronic messages. The secure messaging engagement hub has a natural language processor that structures an unstructured electronic message. The natural language processor structures the unstructured electronic message by using a lexical parser to parse free text within the unstructured electronic message. The natural language processor also may tokenize the parsed free text into tokens representing components of the parsed free text. Message component n-grams are generated based on the tokens representing the components of the parsed free text. The tokens are coded with various metadata tags based on an analysis of the tokens. The metadata tags indicate message components of the tokens. And a structured electronic message corresponding to the unstructured electronic message is generated, the structured electronic message comprising the tokens and the metadata tags.

Abstract: A stage, suitable for use in an analog to digital converter or a digital to analog converter, can have a plurality of slices that can be operated together to form a composite output. The stage can have reduced thermal noise, while each slice on its own has sufficiently small capacitance to respond quickly to changes in digital codes applied to the slice. This feature allows a fast conversion to be achieved without loss of noise performance.

Abstract: A stage, suitable for use in and analog to digital converter or a digital to analog converter, comprises a plurality of slices. The slices can be operated together to form a composite output having reduced thermal noise, while each slice on its own has sufficiently small capacitance to respond quickly to changes in digital codes applied to the slice. This allows a fast conversion to be achieved without loss of noise performance. The slices can be sub-divided to reduce scaling mismatch between the most significant bit and the least significant bit. A shuffling scheme is implemented that allows shuffling to occur between the sub-sections of the slices without needing to implement a massively complex shuffler.

Abstract: A dither is an uncorrelated signal, usually pseudo-random noise injected into the input of an ADC such that a given input value of the wanted signal becomes spread over a plurality of codes. This reduces the effect of DNL and also smooths the integral non-linearity (INL) response of the ADC. The advantages of introducing dither could be obtained without having to perturb the signal input to the ADC. This avoids the introduction of additional components in the ADC. The dither can be applied to the components used to form a residue of the ADC stage within a pipelined converter. For example, a dither can be applied solely to a DAC part or different dithers can be applied to a ADC and DAC parts respectively. This allows greater flexibility of linearization of the ADC response and the formation of an analog residue by the DAC.

Abstract: Disclosed herein is a secure messaging engagement hub for structuring of unstructured electronic messages. The secure messaging engagement hub has a natural language processor that structures an unstructured electronic message. The natural language processor structures the unstructured electronic message by using a lexical parser to parse free text within the unstructured electronic message. The natural language processor also may tokenize the parsed free text into tokens representing components of the parsed free text. Message component n-grams are generated based on the tokens representing the components of the parsed free text. The tokens are coded with various metadata tags based on an analysis of the tokens. The metadata tags indicate message components of the tokens. And a structured electronic message corresponding to the unstructured electronic message is generated, the structured electronic message comprising the tokens and the metadata tags.

Abstract: Systems and methods are provided for the operation of a personal healthcare management portal operable to provide multiple users secure access to a patient's healthcare information. A selection of a patient healthcare management portal associated with a patient may be received by an application tier. The application tier may receive authentication information associated with the selection of the patient healthcare management portal associated with the patient. The application tier may determine if the authentication information is associated with a users valid login credentials. The application tier may receive a request to access patient information, wherein the patient information includes at least one of records, forms, or services associated with the patient. The application tier may also retrieve the requested patient information. The application tier may communicate the requested information to a client device from which the selection originated.

Abstract: A measuring apparatus including a self test function, the circuit comprising a capacitor; first to fourth switches; a test signal injector; at least one comparator having a signal input and a reference input the first switch being interposed between a first plate of the capacitor and a first input node, the second switch being interposed between a second plate of the capacitor and a second input node, the third switch being interposed between the first plate of the capacitor and the signal input of the comparator and the fourth switch being interposed between the second plate of the capacitor and a voltage reference, wherein the self test function comprises the steps of i) operating the signal injector to produce a first signal representative of an out of range voltage for an expected voltage difference between the first and second input nodes, and using the signal to cause the at least one comparator to place its output in an error state, and to charge the capacitor to the out of range voltage, ii) isolating

Abstract: A measuring apparatus including a self test function, the circuit comprising a capacitor; first to fourth switches; a test signal injector; at least one comparator having a signal input and a reference input the first switch being interposed between a first plate of the capacitor and a first input node, the second switch being interposed between a second plate of the capacitor and a second input node, the third switch being interposed between the first plate of the capacitor and the signal input of the comparator and the fourth switch being interposed between the second plate of the capacitor and a voltage reference, wherein the self test function comprises the steps of i) operating the signal injector to produce a first signal representative of an out of range voltage for an expected voltage difference between the first and second input nodes, and using the signal to cause the at least one comparator to place its output in an error state, and to charge the capacitor to the out of range voltage, ii) isolating

Abstract: A switched-capacitor circuit for use in analog-to-digital conversion samples an input signal with respect to a reference voltage such that it significantly reduces a DAC settling time interval during each bit trial. In one exemplary embodiment, the switched-capacitor circuit having first and second groups of capacitor banks is coupled to a first input of a comparator and to a control circuit which provides control signals such that during a switching sequence, an equal value of capacitance is selected from each of the first and second groups of capacitor banks to reduce the DAC settling time interval, thereby improving the conversion rate.