Patents by Inventor Astrid Lohf
Astrid Lohf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8216525Abstract: A modular microfluidic system includes modules which are arranged next to each other in a row. Every module has a microfluidic part which rests on a contact surface of the module in a locally limited area and is forced against the contact surface by a fastening element. The microfluidic part includes a fluid channel system with fluid connections that are arranged on the top surface of the microfluidic part in edge areas relative to the adjoining microfluidic parts. The fluid connections of adjoining microfluidic parts are interlinked by respective connecting channels in a connecting part bridging the microfluidic parts, wherein the connecting part rests on the microfluidic parts in the edge areas. A clamping part rests against the lower surfaces of the adjoining microfluidic parts and is connected to the connecting part via an additional fastening element in the area between the microfluidic parts.Type: GrantFiled: September 26, 2006Date of Patent: July 10, 2012Assignee: Siemens AktiengesellschaftInventors: Astrid Lohf, Reinhold Schneeberger, Robert Sendner
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Patent number: 8163245Abstract: A microfluidics system for mixing at least two starting materials having a prescribed number of parallel and identical mixing or reaction branches, in which a number of supply ducts corresponding to the number of starting materials open into a mixing or reaction channel. Each of the supply ducts includes an intake line for each starting material, an injection pump for each supply duct and a valve circuit between each intake line for a starting material, where the supply ducts for a respective starting material and a respective injection pump are provided to each respective supply duct. The valve circuit is configured to connect the injection pumps to the suction line in a first valve position, shut off the injection pumps in a second valve position, and to connect the injection pumps to the associated inlet channels in a third valve position. Each of the injection pumps, which are connected to each valve circuit, have a common drive.Type: GrantFiled: June 17, 2008Date of Patent: April 24, 2012Assignee: Siemens AktiengesellschaftInventor: Astrid Lohf
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Patent number: 8146650Abstract: There is described a microfluid system with a microchannel structure for the passage of fluids and a further channel structure separated from the microstructure by means of at least one separating wall for the passage of a heat transfer fluid. The risk of internal leakage in the microfluid system can be recognized in time, by separation of the microchannel structure from a cavity of at least one point by a further separating wall, said separating wall being at least locally weaker than the separating wall between the microchannel structure and the further channel structure and said cavity is connected to a detector device for detection of ingressing fluid.Type: GrantFiled: July 24, 2006Date of Patent: April 3, 2012Assignee: Siemens AktiengesellschaftInventors: Astrid Lohf, Waldemar Wenzel
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Patent number: 7910073Abstract: The microfluidic system is constituted of modules that comprise one microfluidic unit and one corresponding electric control unit each and that are retained on a rear panel unit next to each other in a row. To prevent the formation of accumulation of ignitable or toxic gas mixtures a fluid conduit for a rinsing fluid extends through the rear panel unit. Branches lead from said fluid conduit to the modules, and said branches flowing into respective distributor compartments that extend vertically across the module height in the modules. Said distributor compartments are delimited in relation to the interior of the respective module by a distributor panel that is provide with openings. The interior of the respective module comprises, on its lower or rear surface, an exit opening for the rinsing fluid.Type: GrantFiled: September 28, 2006Date of Patent: March 22, 2011Assignee: Siemens AktiengesellschaftInventors: Astrid Lohf, Reinhold Schneeberger, Waldemar Wenzel
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Publication number: 20100247380Abstract: In order to be able to introduce fluid components extraneous to the system into a modular microfluidic system comprising modules arranged alongside one another which can be connected to one another with fluid connection by connecting parts comprising connecting channels with short connecting paths and good temperature controllability, a module with the following features is provided: the module has a plate-shaped microfluidic part which comprises a fluid channel system and on whose top side, in edge regions to the potentially adjacent modules of the microfluidic system has fluid connections, the fluidic connection to adjacent modules being establishable by means of the connecting parts adjacent in edge regions on the upper side, below the microfluidic part is arranged an insulation vessel which can be filled and flowed through by a temperature control fluid and is concluded at the to by the microfluidic part which serves as a lid.Type: ApplicationFiled: March 28, 2007Publication date: September 30, 2010Inventors: Astrid Lohf, Reinhold Schneeberger, Robert Sendner, Johann Sippl
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Publication number: 20100183482Abstract: A microfluidics system for mixing at least two starting materials having a prescribed number of parallel and identical mixing or reaction branches, in which a number of supply ducts corresponding to the number of starting materials open into a mixing or reaction channel. Each of the supply ducts includes an intake line for each starting material, an injection pump for each supply duct and a valve circuit between each intake line for a starting material, where the supply ducts for a respective starting material and a respective injection pump are provided to each respective supply duct. The valve circuit is configured to connect the injection pumps to the suction line in a first valve position, shut off the injection pumps in a second valve position, and to connect the injection pumps to the associated inlet channels in a third valve position. Each of the injection pumps, which are connected to each valve circuit, have a common drive.Type: ApplicationFiled: June 17, 2008Publication date: July 22, 2010Applicant: Siemens AGInventor: Astrid Lohf
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Publication number: 20100021345Abstract: There is described a modular microfluidic system with the following features: Modules are arranged next to each other in a row. Every module has a microfluidic part which rests on a contact surface of the module in a locally limited area and is forced against the same by means of a fastening element. The microfluidic part comprises a fluid channel system with fluid connections that are arranged on the top surface of the microfluidic part in edge areas relative to the adjoining microfluidic parts. The fluid connections of adjoining microfluidic parts are interlinked by respective connecting channels in a connecting part bridging the microfluidic parts, said connecting part resting on the microfluidic parts in the edge areas. A clamping part rests against the lower surfaces of the adjoining microfluidic parts and is connected to the connecting part via an additional fastening element in the area between the microfluidic parts.Type: ApplicationFiled: September 26, 2006Publication date: January 28, 2010Inventors: Astrid Lohf, Reinhold Schneeberger, Robert Sendner
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Publication number: 20100008834Abstract: There is described a microfluid system with a microchannel structure for the passage of fluids and a further channel structure separated from the microstructure by means of at least one separating wall for the passage of a heat transfer fluid. The risk of internal leakage in the microfluid system can be recognized in time, by separation of the microchannel structure from a cavity of at least one point by a further separating wall, said separating wall being at least locally weaker than the separating wall between the microchannel structure and the further channel structure and said cavity is connected to a detector device for detection of ingressing fluid.Type: ApplicationFiled: July 24, 2006Publication date: January 14, 2010Inventors: Astrid Lohf, Waldemar Wenzel
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Publication number: 20090126504Abstract: The microfluidic system is constituted of modules that comprise one microfluidic unit and one corresponding electric control unit each and that are retained on a rear panel unit next to each other in a row. To prevent the formation of accumulation of ignitable or toxic gas mixtures a fluid conduit for a rinsing fluid extends through the rear panel unit. Branches lead from said fluid conduit to the modules, and said branches flowing into respective distributor compartments that extend vertically across the module height in the modules. Said distributor compartments are delimited in relation to the interior of the respective module by a distributor panel that is provide with openings. The interior of the respective module comprises, on its lower or rear surface, an exit opening for the rinsing fluid.Type: ApplicationFiled: September 28, 2006Publication date: May 21, 2009Inventors: Astrid Lohf, Reinhold Schneeberger, Waldemar Wenzel
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Publication number: 20090010820Abstract: In one aspect, a micro-fluidic system consisting of modules that are arranged side by side in a row, each module containing a micro-fluidic unit and an associated electric control unit is provided. The rear faces of the modules lie against a common vertical rear wall unit and are held against the unit. In the modules, the respective control unit is located in the vicinity of the rear face and the micro-fluidic unit is situated in a region that is remote from the rear face. The control units can be connected to an electric line bus that runs through the rear wall unit via electric connectors that are located on the rear faces of the modules and on the rear wall unit and the micro-fluidic units of two respective neighboring modules are interconnected to allow the passage of fluid via a connecting part that contains connection channels and that spans the relevant modules.Type: ApplicationFiled: May 6, 2005Publication date: January 8, 2009Inventors: Udo Fehm, Astrid Lohf, Hermann Ruhl, Reinhold Schneeberger, Johann Sippl, Waldemar Wenzel
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Publication number: 20060228276Abstract: Parallel flow chemical processing systems, such as parallel flow chemical reaction systems are disclosed. These systems are adapted to simultaneously and independently vary temperature between separate flow channels, preferably by employing separate, individual heating elements in thermal communication with each of four or more parallel flow reactors. The flow reactors are preferably isolated from each other using a thermal isolation system comprising fluid-based heat exchange. In preferred embodiments, the axial heat flux can be fixedly or controllably varied.Type: ApplicationFiled: June 6, 2006Publication date: October 12, 2006Applicant: Symyx Technologies, Inc.Inventors: H. Bergh, Shenheng Guan, James Engstrom, Steffen Hardt, Astrid Lohf, Frank Michel
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Publication number: 20060225864Abstract: In order to diagnose obstructions in channels of a micro heat exchanger, at least one temperature sensor is externally placed on the micro heat exchanger and an evaluating device is connected to this sensor. Said evaluating device diagnoses an obstruction based on changes in the measured temperature in the event of unchanged entry parameters of the fluids involved in the heat exchange.Type: ApplicationFiled: January 21, 2004Publication date: October 12, 2006Inventors: Herbert Grieb, Astrid Lohf
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Patent number: 7118917Abstract: Parallel flow chemical processing systems, such as parallel flow chemical reaction systems are disclosed. These systems are adapted to simultaneously and independently vary temperature between separate flow channels, preferably by employing separate, individual heating elements in thermal communication with each of four or more parallel flow reactors. The flow reactors are preferably isolated from each other using a thermal isolation system comprising fluid-based heat exchange. In preferred embodiments, the axial heat flux can be fixedly or controllably varied.Type: GrantFiled: March 7, 2002Date of Patent: October 10, 2006Assignee: Symyx Technologies, Inc.Inventors: H. Sam Bergh, Shenheng Guan, James R. Engstrom, Steffen Hardt, Astrid Lohf, Frank Michel
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Patent number: 7080666Abstract: A system for processing fluids, the system having a unit (1) for supplying and discharging the fluids. The unit has a plurality of fluid lines terminating in a plurality of fluid ports, an assembly side (3) with the plurality of fluid ports terminating therein. The system also has at least one device (4) in which at least one of the fluids is processed. The at least one device is operable to be mounted on the assembly side and further operable to be coupled to the plurality of fluid ports (11, 12, 13, 14). The at least one device has a plurality of components (29, 30, 31) performing a plurality of functions related to the processing of the at least one of the fluids. The components are mounted on the assembly side in superimposed planes. The fluid ports supply and discharging the fluids to and from the components. The fluid ports have different lengths and extend from the assembly side (3) to at least one of the components (29, 30).Type: GrantFiled: September 21, 2004Date of Patent: July 25, 2006Assignee: Siemens AktiengesellschaftInventors: Josef Burger, Oliver Heel, Astrid Lohf
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Patent number: 6982064Abstract: Known static micromixers that work according to the principle of multilamination allow for a rapid mixing by diffusion. The invention provides a means for substantially increasing the throughput of known micromixers. To this end, the inventive micromixer for mixing two or more reactants comprises microstructures that define mixer cells. Each of said mixer cells is provided with a feeding chamber which adjoins at least two groups of digital channels. Said channels intermesh with the digital channels of the groups adjoining the feeding channels in a comb-like manner, thereby producing mixing zones]. Outlet ports are located above said mixing zones, said outlet ports extending perpendicularly to the digital channels and discharging the product. The inventive micromixer is especially useful for the large-scale production of mixtures, dispersions and emulsions.Type: GrantFiled: June 10, 2000Date of Patent: January 3, 2006Assignee: Institut fur Mikrotechnik Mainz GmbHInventors: Wolfgang Ehrfeld, Frank Michel, Astrid Lohf, Volker Graeff
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Publication number: 20050139262Abstract: A system for processing fluids, the system having a unit (1) for supplying and discharging the fluids. The unit has a plurality of fluid lines terminating in a plurality of fluid ports, an assembly side (3) with the plurality of fluid ports terminating therein. The system also has at least one device (4) in which at least one of the fluids is processed. The at least one device is operable to be mounted on the assembly side and further operable to be coupled to the plurality of fluid ports (11, 12, 13, 14). The at least one device has a plurality of components (29, 30, 31) performing a plurality of functions related to the processing of the at least one of the fluids. The components are mounted on the assembly side in superimposed planes. The fluid ports supply and discharging the fluids to and from the components. The fluid ports have different lengths and extend from the assembly side (3) to at least one of the components (29, 30).Type: ApplicationFiled: September 21, 2004Publication date: June 30, 2005Inventors: Josef Burger, Oliver Heel, Astrid Lohf
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Publication number: 20020170976Abstract: Parallel flow chemical processing systems, such as parallel flow chemical reaction systems are disclosed. These systems are adapted to simultaneously and independently vary temperature between separate flow channels, preferably by employing separate, individual heating elements in thermal communication with each of four or more parallel flow reactors. The flow reactors are preferably isolated from each other using a thermal isolation system comprising fluid-based heat exchange. In preferred embodiments, the axial heat flux can be fixedly or controllably varied.Type: ApplicationFiled: March 7, 2002Publication date: November 21, 2002Inventors: H. Sam Bergh, Shenheng Guan, James R. Engstrom, Steffen Hardt, Astrid Lohf, Frank Michel