Abstract: A coil spring includes a wire rod and an elastic coat provided on the wire rod. The coil spring includes a coil section including a plurality of coil portions. The wire rod includes a round cross-sectional portion, a cross-section varying portion, and a rectangular cross-sectional portion along the longitudinal direction of the wire rod. The cross section of the rectangular cross-sectional portion is substantially square and has a first plane and a second plane. The first plane and the second plane oppose each other in the coil section. The elastic coat is provided on at least one of the first plane and the second plane. The elastic coat is continuous from the round cross-sectional portion to the cross-sectional variation portion and the rectangular cross-sectional portion.

Abstract: A motorcycle includes a transmission, a first measuring unit, a second measuring unit, and a controller. The transmission is configured to automatically shift gears between a driving shaft and a driven shaft to transmit power from the driving shaft to the driven shaft. The first measuring unit is configured to measure the magnitude of a roll angle of a vehicle body. The second measuring unit is configured to measure the angular velocity of the roll angle of the vehicle body. The controller is configured to inhibit the transmission from shifting gears, based on the magnitude and the angular velocity of the roll angle. This configuration provides a motorcycle that enables gear shift control with more detailed response to a situation of a vehicle body.

Abstract: A motorcycle includes a transmission, a first measuring unit, a second measuring unit, and a controller. The transmission is configured to automatically shift gears between a driving shaft and a driven shaft to transmit power from the driving shaft to the driven shaft. The first measuring unit is configured to measure the magnitude of a roll angle of a vehicle body. The second measuring unit is configured to measure the angular velocity of the roll angle of the vehicle body. The controller is configured to inhibit the transmission from shifting gears, based on the magnitude and the angular velocity of the roll angle. This configuration provides a motorcycle that enables gear shift control with more detailed response to a situation of a vehicle body.

Abstract: A vehicle control device includes an information acquisition unit that acquires road surface condition information indicative of a road surface condition determined on the basis of a sound acquired by a microphone, a storage unit in which there is stored control content in accordance with the road surface condition, and a control unit which controls a drive unit provided on a vehicle, on the basis of the control content in accordance with the road surface condition indicated by the road surface condition information.

Abstract: A vehicle power output device for driving a first and second rotary electric machine in an efficient range in a wide driving region and for eliminating the need for a complicated mechanism and control. A planetary gear mechanism combines the rotational drive force of a first shaft rotationally driven by a first rotary electric machine and the rotational drive force of a second shaft rotationally driven by a second rotary electric machine and transmits the combined rotational drive force to a drive shaft with the rotational speed increased. The rotational drive force of the second shaft in the forward direction is transmitted to the planetary gear mechanism via a first one-way clutch unit and a first power transmitting mechanism. The rotational drive force of the second shaft in the opposite direction is transmitted to the drive shaft via a second one-way clutch unit and a second power transmitting mechanism.

Abstract: An electrically-operated two wheeled vehicle provided with a swing unit which pivotally supports a drive wheel WR. The swing unit includes: a first rotary electric machine having a first rotor; a second rotary electric machine having a second rotor; and a planetary gear mechanism which combines a rotational drive force of the first and second rotors to each other and transmits a product of rotational drive forces to a drive wheel WR in a state where a rotational speed is increased. The first and second rotary electric machines are arranged parallel to each other in the longitudinal direction of a vehicle such that an axis Ax2 of the second rotor is positioned in front of an axis Ax1 of the first rotor along the vehicle body. This arrangement prevents a height position of a lower surface of a swing unit from becoming excessively low.

Abstract: An electrically-operated two wheeled vehicle provided with a swing unit which pivotally supports a drive wheel WR. The swing unit includes: a first rotary electric machine having a first rotor; a second rotary electric machine having a second rotor; and a planetary gear mechanism which combines a rotational drive force of the first and second rotors to each other and transmits a product of rotational drive forces to a drive wheel WR in a state where a rotational speed is increased. The first and second rotary electric machines are arranged parallel to each other in the longitudinal direction of a vehicle such that an axis Ax2 of the second rotor is positioned in front of an axis Ax1 of the first rotor along the vehicle body. This arrangement prevents a height position of a lower surface of a swing unit from becoming excessively low.

Abstract: A vehicle power output device for driving a first and second rotary electric machine in an efficient range in a wide driving region and for eliminating the need for a complicated mechanism and control. A planetary gear mechanism combines the rotational drive force of a first shaft rotationally driven by a first rotary electric machine and the rotational drive force of a second shaft rotationally driven by a second rotary electric machine and transmits the combined rotational drive force to a drive shaft with the rotational speed increased. The rotational drive force of the second shaft in the forward direction is transmitted to the planetary gear mechanism via a first one-way clutch unit and a first power transmitting mechanism. The rotational drive force of the second shaft in the opposite direction is transmitted to the drive shaft via a second one-way clutch unit and a second power transmitting mechanism.

Abstract: A diagnostic agent for pancreatic exocrine function comprising a dipeptide represented by the following formula (I): X1—R1—Y1??(I) or a pharmaceutically acceptable salt thereof, wherein X1 is a protecting group, R1 is a phenylalanine, glutamine, valine, tyrosine, methionine, serine or threonine residue, and Y1 is a 13C-labeled alanine molecule optionally having a protecting group.

Abstract: A preparation for the diagnosis of pancreatic exocrine function by determining the amount in which a substance administered to a subject or a degradation product or metabolite thereof migrates into the blood and/or is excreted out of the body, wherein the substance is carried by a carrier and released from the carrier when exposed to the action of a pancreatic exocrine function-related factor.

Abstract: The present invention provides a 13C-labeled oligosaccharide or polysaccharide or a salt thereof excluding U—13C-maltose, 13C-starch, 1-13C-maltotetraose and 1-13C-amylose; a derivative of the 13C-labeled oligosaccharide or polysaccharide or salt thereof; a 13C-labeled inclusion complex or a salt thereof, which comprises a cyclodextrin or a modified derivative thereof as a host molecule; a 13C- or 14C-labeled fluorescein ester compound or a salt thereof; and a diagnostic agents for pancreatic exocrine function comprising these compounds 13C- or 14C-labeled.

Abstract: The present invention provides a diagnostic agent for evaluating gastric emptying function and/or small intestinal absorptive capacity which imposes less burden to subjects and which is capable of obtaining objective test results in a short period of time. A diagnostic agent for evaluating gastric emptying function and/or small intestinal absorptive capacity, comprising succinic acid labeled with a stable isotope 13C or a pharmaceutically acceptable salt thereof.

Abstract: A preparation for the diagnosis of pancreatic exocrine function by determining the amount in which a substance administered to a subject or a degradation product or metabolite thereof migrates into the blood and/or is excreted out of the body, wherein the substance is carried by a carrier and released from the carrier when exposed to the action of a pancreatic exocrine function-related factor.

Abstract: A diagnostic reagent for use in the evaluation of a pharmacological effect of a medicine containing a pharmaceutical agent including an enzyme, an enzyme inhibitor or a receptor ligand or a prodrug of the pharmaceutical agent is provided. Further, a method of screening pharmaceutical agents each comprising an enzyme, an enzyme inhibitor or a receptor ligand and/or prodrugs of the pharmaceutical agents is provided.

Abstract: The present invention provides a 13C-labeled oligosaccharide or polysaccharide or a salt thereof excluding U-13C-maltose, 13C-starch, 1-13C-maltotetraose and 1-13C-amylose; a derivative of the 13C-labeled oligosaccharide or polysaccharide or salt thereof; a 13C-labeled inclusion complex or a salt thereof, which comprises a cyclodextrin or a modified derivative thereof as a host molecule; a 13C- or 14C-labeled fluorescein ester compound or a salt thereof; and a diagnostic agents for pancreatic exocrine function comprising these compounds 13C- or 14C-labeled.

Abstract: A diagnostic agent for pancreatic exocrine function comprising a dipeptide represented by the following formula (I): X1—R113 Y1??(I) or a pharmaceutically acceptable salt thereof, wherein X1 is a protecting group, R1 is a phenylalanine, glutamine, valine, tyrosine, methionine, serine or threonine residue, and Y1 is a 13C-labeled alanine molecule optionally having a protecting group.

Abstract: A diagnostic agent for pancreatic exocrine function comprising an amino acid or a peptide containing at least one 13C or 14C atom, or a pharmaceutically acceptable salt thereof other than Bz-Tyr-13C-PABA is provided. A 13C- or 14C-labeled compound represented by the following formula (II): X2—R2—Y2—Z1 ??(II) or a salt thereof, wherein X2 is a hydrogen atom or a protecting group, R2 is a peptide of 2 to 5 amino acids, an amino acid or a single bond, Y2 is an amino acid, Z1 is an amino acid optionally having a protecting group, and at least one of the amino acids in R2, Y2 and Z1, or at least one of the protecting groups in X2 and Z1 when the protecting groups contain a carbon atom, is 13C or 14C-labeled.

Abstract: A diagnostic agent for pancreatic exocrine function comprising a dipeptide represented by the following formula (I): X1—R1—Y1??(I) or a pharmaceutically acceptable salt thereof, wherein X1 is a protecting group, R1 is a phenylalanine, glutamine, valine, tyrosine, methionine, serine or threonine residue, and Y1 is a 13C-labeled alanine molecule optionally having a protecting group.

Abstract: A preparation for the diagnosis of pancreatic exocrine function by determining the amount in which a substance administered to a subject or a degradation product or metabolite thereof migrates into the blood and/or is excreted out of the body, wherein the substance is carried by a carrier and released from the carrier when exposed to the action of a pancreatic exocrine function-related factor.

Abstract: A preparation for the diagnosis of pancreatic exocrine function by determining the amount in which a substance administered to a subject or a degradation product or metabolite thereof migrates into the blood and/or is excreted out of the body, wherein the substance is carried by a carrier and released from the carrier when exposed to the action of a pancreatic exocrine function-related factor.