Patents by Inventor Atan Gross

Atan Gross has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING DISEASES RELATED TO MITOCHONDRIAL FUNCTION
    Publication number: 20180042994
    Abstract: Uses of agent which downregulate an activity or expression of a component participating in the mitochondrial apoptotic pathway are disclosed.
    Type: Application
    Filed: November 17, 2015
    Publication date: February 15, 2018
    Inventors: Atan GROSS, Yehudit ZALTSMAN, Liat PINKAS, Maria MARYANOVICH, Liat BUZAGLO, Antonella RUGGIERO, Amir BAHAT, Andres GOLDMAN, Michael MULLOKANDOV
  • Compositions and methods for regulating apoptosis
    Publication number: 20090124564
    Abstract: Methods and pharmaceutical compositions for regulating apoptosis and treating pathologies associated with disregulated apoptosis are provided. Specifically the present invention provides agents capable of modulating the expression of an MCD-containing protein (e.g., Mtch2) capable of tBID binding activity and/or the tBID binding activity of the MCD-containing protein.
    Type: Application
    Filed: January 5, 2006
    Publication date: May 14, 2009
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Atan Gross, Michal Grinberg, Yehudit Zaltsman
  • Modulation of apoptosis with bid
    Patent number: 6326354
    Abstract: A novel p15 BID polypeptide having cell death agonist activity is disclosed. The p15 BID polypeptide is produced by caspase-cleavage of BID in cells undergoing cell death mediated by TNF or FAS receptors. The p15 BID is useful in methods for modulating death of a target cell which comprise treating the cell with p15 BID. Methods for inhibiting cell death are also described which involve treating a target cell with a mutant p15 BID lacking cell death agonist activity.
    Type: Grant
    Filed: August 19, 1998
    Date of Patent: December 4, 2001
    Assignee: Washington University
    Inventors: Atan Gross, Stanley J. Korsmeyer