Patents by Inventor Atsuhisa Nishimura

Atsuhisa Nishimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BACILLUS BACTERIUM, INTERLEUKIN-22 PRODUCTION INDUCING AGENT, SKIN BARRIER FUNCTION ENHANCING AGENT
    Publication number: 20230263841
    Abstract: A Bacillus bacterium that induces the production of interleukin-22 is provided. The Bacillus bacterium that induces the production of interleukin-22.
    Type: Application
    Filed: March 16, 2023
    Publication date: August 24, 2023
    Applicants: ICHIBIKI CO., LTD., NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
    Inventors: Toshihiko Kumazawa, Atsuhisa Nishimura, Noriyuki Asai, Takahiro Adachi
  • Salt-tolerant , method of culturing salt-tolerant , and immunostimulant
    Patent number: 11260085
    Abstract: There is provided a salt-tolerant Lactobacillus having high foodstuff suitability, being easily produced, and having an immunostimulatory action. Salt-tolerant Lactobacillus having an immunostimulatory action with viability and activation potency of B cells.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: March 1, 2022
    Assignees: ICHIBIKI CO., LTD., NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
    Inventors: Toshihiko Kumazawa, Atsuhisa Nishimura, Noriyuki Asai, Takahiro Adachi
  • SALT-TOLERANT LACTOBACILLUS, METHOD OF CULTURING SALT-TOLERANT LACTOBACILLUS, AND IMMUNOSTIMULANT
    Publication number: 20210283200
    Abstract: There is provided a salt-tolerant Lactobacillus having high foodstuff suitability, being easily produced, and having an immunostimulatory action. Salt-tolerant Lactobacillus having an immunostimulatory action with viability and activation potency of B cells.
    Type: Application
    Filed: September 12, 2017
    Publication date: September 16, 2021
    Inventors: Toshihiko Kumazawa, Atsuhisa Nishimura, Noriyuki Asai, Takahiro Adachi
  • LACTIC ACID BACTERIUM, BLOOD IRON INCREASING AGENT, AND ANEMIA IMPROVING AGENT
    Publication number: 20210228651
    Abstract: A lactic acid bacterium is provided which has high foodstuff suitability, easy to manufacture, and can increase the blood iron concentration, thereby improving anemia. A lactic acid bacterium of salt-tolerant that increases the blood iron concentration.
    Type: Application
    Filed: August 16, 2019
    Publication date: July 29, 2021
    Applicant: ICHIBIKI CO., LTD.
    Inventors: Atsuhisa Nishimura, Noriyuki Asai, Toshihiko Kumazawa
  • BACILLUS BACTERIUM, INTERLEUKIN-22 PRODUCTION INDUCING AGENT, SKIN BARRIER FUNCTION ENHANCING AGENT
    Publication number: 20210100851
    Abstract: A Bacillus bacterium that induces the production of interleukin-22 is provided. The Bacillus bacterium that induces the production of interleukin-22.
    Type: Application
    Filed: February 15, 2019
    Publication date: April 8, 2021
    Inventors: Toshihiko Kumazawa, Atsuhisa Nishimura, Noriyuki Asai, Takahiro Adachi
  • Method of measuring pyrophosphate
    Patent number: 8105766
    Abstract: Provided is a novel and useful method of measuring pyrophosphate in a sample. There may be provided a novel and useful method of measuring pyrophosphate in a sample using pyruvate orthophosphate dikinase, nicotinamide-nucleotide adenylyltransferase, and dehydrogenase.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: January 31, 2012
    Assignees: Asahi Kasei Pharma Corporation, Ichibiki Co., Ltd.
    Inventors: Shinichi Sakasegawa, Yoshiaki Ikura, Atsuhisa Nishimura, Toshihiko Kumazawa, Shigeyuki Imamura
  • METHOD OF MEASURING PYROPHOSPHATE
    Publication number: 20090246783
    Abstract: Provided is a novel and useful method of measuring pyrophosphate in a sample. There may be provided a novel and useful method of measuring pyrophosphate in a sample using pyruvate orthophosphate dikinase, nicotinamide-nucleotide adenylyltransferase, and dehydrogenase.
    Type: Application
    Filed: February 27, 2009
    Publication date: October 1, 2009
    Applicants: Asahi Kasei Pharma Corporation, Ichibiki Co., Ltd.
    Inventors: Shinichi SAKASEGAWA, Yoshiaki Ikura, Atsuhisa Nishimura, Toshihiko Kumazawa, Shigeyuki Imamura
  • Hemoglobin A1c determination method, enzyme to be used therefor, and production method thereof
    Patent number: 7588910
    Abstract: There is provided a method for specifically determining a glycated ?-chain N-terminal of glycated hemoglobin using enzymes without a separation operation, and a determination reagent kit therefor. A protease that cleaves a glycated amino acid and/or a glycated peptide from a glycated ?-chain N-terminal without substantially cleaving a glycated amino acid or a glycated peptide from a glycated ?-chain N-terminal of glycated hemoglobin or a fragment thereof is screened. The method of specifically determining a glycated ?-chain N-terminal of glycated hemoglobin and the determination reagent kit are provided by using the protease obtained by the screening method. According to the present invention, a glycated ?-chain N-terminal of glycated hemoglobin can specifically be determined without a separation operation.
    Type: Grant
    Filed: May 21, 2004
    Date of Patent: September 15, 2009
    Assignees: Asahi Kasei Pharma Corporation, Ichibiki Co., Ltd.
    Inventors: Takeshi Matsuoka, Shinji Koga, Takuji Kouzuma, Issei Yoshioka, Atsuhisa Nishimura, Homare Itou, Toshihiko Kumazawa, Takashi Kuroyanagi
  • Hemoglobin A1c Determination Method, Enzyme to be Used therefor, and Production Method Thereof
    Publication number: 20080113381
    Abstract: There is provided a method for specifically determining a glycated ?-chain N-terminal of glycated hemoglobin using enzymes without a separation operation, and a determination reagent kit therefor. A protease that cleaves a glycated amino acid and/or a glycated peptide from a glycated ?-chain N-terminal without substantially cleaving a glycated amino acid or a glycated peptide from a glycated ?-chain N-terminal of glycated hemoglobin or a fragment thereof is screened. The method of specifically determining a glycated ?-chain N-terminal of glycated hemoglobin and the determination reagent kit are provided by using the protease obtained by the screening method. According to the present invention, a glycated ?-chain N-terminal of glycated hemoglobin can specifically be determined without a separation operation.
    Type: Application
    Filed: May 21, 2004
    Publication date: May 15, 2008
    Inventors: Takeshi Matsuoka, Shinji Koga, Takuji Kouzuma, Issei Yoshioka, Atsuhisa Nishimura, Homare Itou, Toshihiko Kumazawa, Takashi Kuroyanagi