Abstract: The switching unit has the switching member on the front side and the switching member on the back side which are mutually mechanically and electrically connected when mounted on the spoke portion of the steering wheel, and is designed such tat when the switching members are assembled in one unit, the elastic electrode portion on one side comes into elastic contact with the electrode pattern portion on the other side. The switching members, therefore, are not required to be assembled into one unit prior to installation to the steering wheel, being little restricted in shape and size. In addition it is possible to dispense with such a complicated operation as electrically connecting the switching members by a wiring harness after installation to the steering wheel, therefore improving the ease of installation. Furthermore, since there is no necessity to form a through hole in the spoke portion of the steering wheel, the steering wheel will not be deteriorated in mechanical strength.

Abstract: This invention relates to a cycloalka[b]pyridine-3-carbonylguanidine derivative represented by the following general formula (1): and a salt thereof, which can provide a drug having sodium/proton (Na+/H+) exchange transport inhibitory action.

Abstract: A turn signal switch includes a housing having a cam portion; a control lever turnably supported in the housing; a driving element for holding the control lever at three positions, first and second operating positions and a neutral position, in cooperation with the cam portion; a lever member turnably supported in the housing so as to return the control lever from the first and second operating positions to the neutral position; and a spring member for elastically urging the lever member toward a canceling projection that turns together with the steering wheel. The lever member is retracted outside the locus of turning of the canceling projection by the control lever when the control lever is in the neutral position, and is advanced inside the locus of turning of the canceling projection by the urging force of the spring member so that the spring member is in elastic contact with the lever member at one point when the control lever is in the first or second operating position.

Abstract: A mechanism for releasing an excess load with a simple construction when the excess load is applied during a cancel operation for automatically restoring an operating lever. A movable member is swingably supported by a holder mounted to an operating lever, and a spring is provided between the movable member and a driving member, whereby the movable member is biased toward the stable position of the holder, and the driving member is brought into press contact with a cam surface of a case. When the operating lever is rotated from the neutral position to the operating position, the driving member slides on the cam surface and is held in the operating position, and a first lever member comes into the rotation path of a cancel protrusion. When in this condition the steering wheel is turned in the opposite direction, the cancel protrusion abuts the first lever member to rotate during the return operation thereof, and with that, a second lever member rotates.

Abstract: A switch lever is rotatably supported on first and second cases and is held in one of three positions of right and left ON positions and neutral position by cooperation of a cam face formed on the first case with an actuator provided on the switch lever. On the inside bottom surface of the second case, first and second support pins are provided upright. A first lever member is rotatably supported on the first support pin and a second lever member is rotatably supported on a support pin formed upright on the forward end of the first lever member. In the second lever member are formed first and second long holes, in which the support pin and the second support pin are fitted. A torsion spring is provided to press the second lever member in the longitudinal direction of these long holes. When the switch lever is turned to right or left turn position, the second lever member is moved forward into the path of rotation of a cancel projection by the force of the torsion spring, turning the second lever member.

Abstract: A vehicular knob switch apparatus suitable for the attainment of size reduction and multi-function is provided. An operating knob is attached to a cylindrical housing rotatably from the exterior. Integral with the operating knob is a first gear which is disposed in the circumferential direction of the operating knob. A second gear is brought into mesh with the first gear in such a manner that the respective axes are orthogonal to each other. A support shaft of the second gear is held by a holder which is fixed to the interior of the housing. Also held by the holder is a printed circuit board which is disposed in the axial direction of the operating knob. Rotation of the operating knob is transmitted to a rotary volume through both gears and. The rotary volume is mounted on the printed circuit board, and first and second push switches, which are operated by key tops, respectively, are also mounted on the printed circuit board. The key tops are attached to the housing to allow to be operated from the exterior.

Abstract: A vehicle knob switch apparatus including an operating lever, a cylindrical holder disposed at an end of the operating lever, a plurality of changeover switch portions accommodated in the interior of the holder, a first operating knob, mounted so as to be rotatable substantially coaxially with an axial line of the operating lever and not movable in the axial direction, for operating one of the plurality of changeover switch portions, and a second operating knob, swingably mounted to an end of the holder, for operating the other one of the plurality of changeover switch portions. The vehicle knob switch apparatus has an integrated switch mechanism, allows components to be installed in the vicinity of the steering column after confirmation of functions, and can be reduced in size.

Abstract: A substituted cyclic amine compound represented by the following general formula (1) ##STR1## wherein each of R.sup.1 to R.sup.5 represents a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group or the like, A represents a carbonyl group or a sulfonyl group, B represents a methine moiety or a nitrogen atom, D represents a methine moiety, a nitrogen atom or .dbd.N(.fwdarw.O)-- and n is an integer of 2 to 3; and synthetic methods thereof. The inventive compound is useful in preventing and treating circulatory organ-related diseases such as hypertension, ischemic heart disease, cerebrovascular disease, peripheral circulatory disease and the like.

Abstract: A prostacyclin analogue having the formula: ##STR1## wherein R.sup.1 is --CO.sub.2 R.sup.5 (wherein R.sup.5 is a hydrogen atom, a straight chain or branched alkyl group having from 1 to 12 carbon atoms, an aralkyl group having from 7 to 12 carbon atoms, a cycloalkyl group having from 4 to 7 carbon atoms and unsubstituted or substituted by at least one alkyl group having from 1 to 4 carbon atoms, a substituted or unsubstituted phenyl group, or one equivalent of a cation), or --CONR.sup.6 R.sup.7 (wherein each of R.sup.6 and R.sup.7 is a hydrogen atom or an alkyl group having from 1 to 10 carbon atoms, or R.sup.6 and R.sup.7 together with the adjacent nitrogen atom, form a 5- or 6-membered substituted or unsubstituted hetero ring which may contain a hetero atom other than said nitrogen atom); A is --CH.sub.2 CH.sub.2 CH.sub.2 --, CH.sub.2 --O--CH.sub.2 CH.sub.2 --, --CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 --, --CH.sub.2 CH.sub.2 --O--CH.sub.2 -- or --CH.dbd.CHCH.sub.2 CH.sub. 2 --; B is trans --CH.dbd.CH-- or --C.