Patents by Inventor Atsushi Miyachi

Atsushi Miyachi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANALYSIS METHOD
    Publication number: 20130344524
    Abstract: In a method for detecting a glucagon-secretin family peptide in a sample, the sample is contacted with a cleaving agent capable of digesting the glucagon-secretin family peptide by cleaving a peptide bond of at least one aspartic acid within the glucagon-secretin family peptide and thereby generating a plurality of peptide fragments, at least one of the peptide fragments containing an N-terminal end of the glucagon-secretin family peptide. The peptide fragment that contains the N-terminal end of the glucagon-secretin family peptide is then detected using liquid chromatography and mass spectrometry. The amount of peptide fragment that contains the N-terminal end of the glucagon-secretin family peptide in the sample can then be quantitated using a calibration curve.
    Type: Application
    Filed: March 7, 2012
    Publication date: December 26, 2013
    Applicant: SANWA KAGAKU KENKYUSHO CO., LTD.
    Inventors: Atsushi Miyachi, Yoshika Yasuda, Hiroko Hirooka
  • PEPTIDE FOR IMPROVING BIOSTABILITY OF BIOACTIVE SUBSTANCE, AND BIOACTIVE SUBSTANCE HAVING IMPROVED BIOSTABILITY
    Publication number: 20130123460
    Abstract: The present invention aims at providing a peptide fragment capable of improving biostability of a bioactive substance while maintaining the activity of the bioactive substance, and a bioactive substance to which the peptide fragment is added. The present invention relates to a partial peptide of a GA module having 5 to 25 amino acids, including a partial sequence of a GA module (SEQ ID NO: 1) and the amino acid sequence Ile-Asp-Glu-Ile-Leu (SEQ ID NO: 2), and a bioactive complex in which the partial peptide of the GA module is bound to a bioactive substance. The bioactive substance includes GLP-1, GLP-2, GIP, VIP, somatostatin, amylin, ghrelin, derivatives thereof, and the like.
    Type: Application
    Filed: April 28, 2011
    Publication date: May 16, 2013
    Applicant: SANWA KAGAKU KENKYUSHO CO., LTD.
    Inventors: Masayuki Okamoto, Ryuhji Okamoto, Tomohiro Shigemori, Takayo Murase, Atsushi Miyachi, Mitsuaki Takeuchi, Miyuki Tamura, Hiroshi Kinoshita
  • ISOTOPE LABELING METHODS
    Publication number: 20070037223
    Abstract: The present invention relates to a method for the analysis of differential expression of proteins employing a radioactive label, characterized by cleaving a tag from peptides labeled with a cICAT reagent, separating and purifying the resultant labeled peptides, and performing an analysis in mass spectrometry.
    Type: Application
    Filed: April 21, 2006
    Publication date: February 15, 2007
    Inventors: Isao KANEKO, Megumu Kondo, Atsushi Miyachi, Masayuki Yokota
  • Isotope labeling methods
    Publication number: 20070015222
    Abstract: The present invention relates to a method for the analysis of differential expression of proteins employing a radioactive label, characterized by cleaving a tag from peptides labeled with a cICAT reagent, separating and purifying the resultant labeled peptides, and performing an analysis in mass spectrometry.
    Type: Application
    Filed: March 17, 2006
    Publication date: January 18, 2007
    Inventors: Isao Kaneko, Megumu Kondo, Atsushi Miyachi, Masayuki Yokota
  • Antagonist of MCP-1 function, and compositions and methods of use thereof
    Patent number: 6962926
    Abstract: Compounds of formula A and formula B: and their pharmaceutically acceptable salts, compositions comprising them, methods for their use, and their use in the preparation of medicaments. The compounds are antagonists of MCP-1 function, and are useful in the prevention and treatment of chronic or acute inflammatory or autoimmune diseases, such as multiple sclerosis, and in the prevention and treatment of allergic hypersensitivity disorders.
    Type: Grant
    Filed: August 8, 2003
    Date of Patent: November 8, 2005
    Assignees: Telik, Inc., Sanwa Kagaku Kenkyusho Co., Ltd.
    Inventors: Edgardo Laborde, Louise Robinson, Fanying Meng, Brian T. Peterson, Hugo O. Villar, Steven E. Anuskiewicz, Wenli Ma, Yukiharu Matsumoto, Kunihisa Baba, Hideaki Inagaki, Katsumasa Tanaka, Yoshiro Ishiwata, Shoji Yokochi, Masayuki Okamoto, Takashi Nakamura, Atsushi Miyachi, Mitsuaki Takeuchi, Kouji Matsushima
  • Antagonist of MCP-1 function, and compositions and methods of use thereof
    Publication number: 20040198719
    Abstract: Compounds of formula A and formula B: 1
    Type: Application
    Filed: August 8, 2003
    Publication date: October 7, 2004
    Inventors: Edgardo Laborde, Louise M. Robinson, Fanying Meng, Brian T. Peterson, Hugo O. Villar, Steven E. Anuskiewicz, Wenli Ma, Yukiharu Matsumoto, Kunihisa Baba, Hideaki Inagaki, Katsumasa Tanaka, Yoshiro Ishiwata, Shoji Yokochi, Masayuki Okamoto, Takashi Nakamura, Atsushi Miyachi, Mitsuaki Takeuchi, Kouji Matsushima