Patents by Inventor Atsushi Toyoshima

Atsushi Toyoshima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240124496
    Abstract: The invention provides a method for producing radiolabeled tyrosine derivatives with good purity and stability, by a safe method suitable for industrial production of pharmaceuticals. The invention relates to a method for producing Compound (5) and Radiolabeled Compound (6) as follows: wherein each symbol is as defined in the description.
    Type: Application
    Filed: March 24, 2022
    Publication date: April 18, 2024
    Applicant: OSAKA UNIVERSITY
    Inventors: Yoshifumi SHIRAKAMI, Kazuko KANEDA, Yuichiro KADONAGA, Tadashi WATABE, Atsushi TOYOSHIMA, Koichi FUKASE, Atsushi SHINOHARA, Toshio YAMANAKA, Yutaka KONDOH
  • Patent number: 11795056
    Abstract: Provided is a method capable of separating and purifying astatine-211 in a high yield and dissolving same in a solution. A method for producing astatine-211, including a step of irradiating ? ray to bismuth to produce astatine-211 in the bismuth, and a step of distilling the bismuth that received ? ray irradiation with a carrier gas containing an inert gas, O2 and H2O to separate and purify astatine-211, and dissolving the astatine-211 in a solution.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: October 24, 2023
    Assignee: OSAKA UNIVERSITY
    Inventors: Atsushi Shinohara, Atsushi Toyoshima, Takashi Yoshimura, Akimitsu Kanda
  • Publication number: 20230233705
    Abstract: The present invention relates to a gold nanoparticle-containing medicine, and a treatment of a proliferative disease using the medicine. The present invention also relates to a gold nanoparticle-containing medicine that is bound to an alpha radioactive nucleus, and a treatment of a proliferative disease using the medicine.
    Type: Application
    Filed: May 14, 2021
    Publication date: July 27, 2023
    Applicant: OSAKA UNIVERSITY
    Inventors: Hiroki KATO, Koichi FUKASE, Kazuya KABAYAMA, Atsushi SHIMOYAMA, Yuichiro KADONAGA, Atsushi TOYOSHIMA, Atsushi SHINOHARA, Yasufumi KANEDA, Tomoyuki NISHIKAWA
  • Publication number: 20210210244
    Abstract: There is provided a radionuclide manufacturing system, a computer-readable storage medium storing a radionuclide manufacturing program, a radionuclide manufacturing method, and a terminal device for more stably manufacturing a radionuclide.
    Type: Application
    Filed: March 1, 2019
    Publication date: July 8, 2021
    Applicant: OSAKA UNIVERSITY
    Inventors: Atsushi SHINOHARA, Atsushi TOYOSHIMA, Zijian ZHANG, Akimitsu KANDA, Soichiro ICHIMURA
  • Publication number: 20200290872
    Abstract: Provided is a method capable of separating and purifying astatine-211 in a high yield and dissolving same in a solution. A method for producing astatine-211, including a step of irradiating ? ray to bismuth to produce astatine-211 in the bismuth, and a step of distilling the bismuth that received ? ray irradiation with a carrier gas containing an inert gas, O2 and H2O to separate and purify astatine-211, and dissolving the astatine-211 in a solution.
    Type: Application
    Filed: December 7, 2018
    Publication date: September 17, 2020
    Applicant: OSAKA UNIVERSITY
    Inventors: Atsushi SHINOHARA, Atsushi TOYOSHIMA, Takashi YOSHIMURA, Akimitsu KANDA
  • Patent number: 7449097
    Abstract: The present invention provides an electrophoretic mobility measuring apparatus capable of conducting measurement with high sensitivity with optical attenuation reduced by incidence of light through the electrode face. This apparatus comprises a transparent electrode 63 forming a part of a cell wall of a cell 6 capable of confining a sample, and the other electrode 62 opposite to the transparent electrode 63. A voltage is applied across these electrodes 62, 63, and light is incident upon the inside of the cell 6 through the transparent electrode 63. The scattering light which scatters from a sample S at a predetermined angle ? with respect to the incident angle, is received through the transparent electrode 63. The Doppler displacement is then measured based on the difference in frequency between the incident light and the outgoing light.
    Type: Grant
    Filed: February 24, 2004
    Date of Patent: November 11, 2008
    Assignee: Otsuka Electronics Co., Ltd.
    Inventors: Mitsunao Sekiwa, Kazunori Tsutsui, Katsuhiro Morisawa, Takashi Fujimoto, Atsushi Toyoshima
  • Publication number: 20040251134
    Abstract: The present invention provides an electrophoretic mobility measuring apparatus capable of conducting measurement with high sensitivity with optical attenuation reduced by incidence of light through the electrode face. This apparatus comprises a transparent electrode 63 forming a part of a cell wall of a cell 6 capable of confining a sample, and the other electrode 62 opposite to the transparent electrode 63. A voltage is applied across these electrodes 62, 63, and light is incident upon the inside of the cell 6 through the transparent electrode 63. The scattering light which scatters from a sample S at a predetermined angle &thgr; with respect to the incident angle, is received through the transparent electrode 63. The Doppler displacement is then measured based on the difference in frequency between the incident light and the outgoing light.
    Type: Application
    Filed: February 24, 2004
    Publication date: December 16, 2004
    Inventors: Mitsunao Sekiwa, Kazunori Tsutsui, Katsuhiro Morisawa, Takashi Fujimoto, Atsushi Toyoshima