Abstract: Provided is a medicinal composition having excellent stability, the medicinal composition comprising 3-{[(2S)-2-amino-2-carboxyethyl]carbamoylamino}-5-chloro-4-methylbenzenesulfonic acid, a pharmaceutically acceptable salt thereof, or a solvate thereof, wherein the medicinal composition has a pH of 8.0 or less.

Abstract: A medicinal composition for preventing or treating secondary hyperparathyroidism under maintenance dialysis, said medicinal composition comprising 3-{[(2S)-2-amino-2-carboxyethyl]carmaboylamino}-5-chloro-4-methylbenzenesulfonic acid or a pharmaceutically acceptable salt thereof, or a solvate of the same which is to be administered by a predefined route in a predefined dosage. According to the present invention, it is possible to provide a prophylactic or therapeutic agent for secondary hyperparathyroidism under maintenance dialysis, said agent showing reduced side effects or no significant accumulation. This medicinal agent allows easy administration management and has a high safety compared with conventional products.

Abstract: A medicinal composition for preventing or treating secondary hyperparathyroidism under maintenance dialysis, said medicinal composition comprising 3-{[(2S)-2-amino-2-carboxyethyl]carmaboylamino}-5-chloro-4-methylbenzenesulfonic acid or a pharmaceutically acceptable salt thereof, or a solvate of the same which is to be administered by a predefined route in a predefined dosage. According to the present invention, it is possible to provide a prophylactic or therapeutic agent for secondary hyperparathyroidism under maintenance dialysis, said agent showing reduced side effects or no significant accumulation. This medicinal agent allows easy administration management and has a high safety compared with conventional products.

Abstract: Provided is a compound having ?4 integrin inhibitory action. The compound is a sulfonamide derivative represented by the following formula (I), or pharmaceutically acceptable salt thereof: where R1 to R5, e to h, D, and B represent those as described in the specification.

Abstract: Provided is a compound having ?4 integrin inhibitory action. The compound is a sulfonamide derivative represented by the following formula (I), or pharmaceutically acceptable salt thereof: where R1 to R5, e to h, D, and B represent those as described in the specification.

Abstract: Disclosed is a pneumatic tire provided with a temperature-sensitive color-changing rubber part formed through vulcanization of a rubber composition that comprises a rubber component, and temperature-sensitive color-changing microcapsules with, as encapsulated therein, a temperature-sensitive color-changing component of which the color may reversibly change with temperature change, and that is obtained by directly mixing and dispersing the microcapsules in the rubber component. The temperature-sensitive color-changing rubber part may constitute at least a part of the tire body. The rubber part may be a coating film formed by applying a coating composition comprising the rubber composition onto the outer surface of a tire, and shaping it through vulcanization along with the tire body. Further, it may constitute a display layer of a color seal to be stuck to the outer surface of a tire.

Abstract: An air bearing drive system has a base, a moving portion, an air bearing for forming an air film gap between the base and the moving portion, air nozzles and a suction inlet. The air nozzles and suction inlet are formed on the base. The air nozzles blow air toward the moving portion so as to exert a levitation force on the moving portion. The suction inlet applies suction to the air film gap so as to attract the moving portion toward the base and thereby exert an attraction force on the moving portion. An air supplying device supplies air to the air nozzles. A vacuum source applies suction to the suction inlets. Two adjusting devices are adapted to adjust the levitation force produced by the air issuing from the air nozzles and the attraction force of air drawn into the suction inlet so as to provide an accurate and low cost air bearing drive system.

Abstract: A compensation method according to the present invention includes: a traverse linearity data calculating step for measuring a master workpiece (MW) of which profile data is value-specified in advance while moving a sensor (7) using a linear movement mechanism (4, 5) of a measuring device (1) and for subtracting the previously value-specified profile data from the measurement data of the master workpiece to obtain a traverse linearity data of the linear movement mechanism; a workpiece measurement data calculating step for measuring the workpiece while moving the sensor by the linear movement mechanism of the measuring device to obtain a measurement data of the workpiece; and a workpiece profile calculating step for subtracting the traverse linearity data from the workpiece measurement data to obtain a true value data of the workpiece.

Abstract: An eccentricity adjusting motor (83) is provided in eccentricity adjusting device (17) that adjusts an eccentricity in a work. A tilt adjusting motor (86) is also provided in tilt adjusting device (18) that adjusts a tilt of the work. A processor (2) computes the eccentricity and tilt of the work, based on which eccentricity/tilt compensating means (105, 106) control the motors (83, 86) to compensate the eccentricity and tilt of the work.

Abstract: An air bearing drive system has a base, a moving portion, an air bearing for forming an air film gap between the base and the moving portion, air nozzles and a suction inlet. The air nozzles and suction inlet are formed on the base. The air nozzles blow air toward the moving portion so as to exert a levitation force on the moving portion. The suction inlet applies suction to the air film gap so as to attract the moving portion toward the base and thereby exert an attraction force on the moving portion. An air supplying device supplies air to the air nozzles. A vacuum source applies suction to the suction inlets. Two adjusting devices are adapted to adjust the levitation force produced by the air issuing from the air nozzles and the attraction force of air drawn into the suction inlet so as to provide an accurate and low cost air bearing drive system.

Abstract: An eccentricity adjusting motor (83) is provided in eccentricity adjusting device (17) that adjusts an eccentricity in a work. A tilt adjusting motor (86) is also provided in tilt adjusting device (18) that adjusts a tilt of the work. A processor (2) computes the eccentricity and tilt of the work, based on which eccentricity/tilt compensating means (105, 106) control the motors (83, 86) to compensate the eccentricity and tilt of the work.

Abstract: A compensation method according to the present invention includes: a traverse linearity data calculating step for measuring a master workpiece (MW) of which profile data is value-specified in advance while moving a sensor (7) using a linear movement mechanism (4, 5) of a measuring device (1) and for subtracting the previously value-specified profile data from the measurement data of the master workpiece to obtain a traverse linearity data of the linear movement mechanism; a workpiece measurement data calculating step for measuring the workpiece while moving the sensor by the linear movement mechanism of the measuring device to obtain a measurement data of the workpiece; and a workpiece profile calculating step for subtracting the traverse linearity data from the workpiece measurement data to obtain a true value data of the workpiece.

Abstract: A surface-following type measuring machine is provided, which is capable of setting the measuring force to a proper value in an efficient and accurate manner without imposing a burden on the operator in exchanging at least one of the stylus and stylus holder according to the surface contour of an object to be measured. A main body is disposed for movement relative to an object to be measured. A measuring arm is supported by the main body for displacement relative thereto, and carries at one end thereof a stylus holder and a stylus in a manner permitting replacement of the stylus holder and the stylus. Displacement of the measuring arm is detected by a displacement detecting device. The measuring force acting upon the measuring arm is adjusted by a measuring force adjusting device. A memory stores a measuring force command value table having a plurality of command values of the measuring force corresponding respectively to combinations of plural kinds of the stylus holder and plural kinds of the stylus.

Abstract: A driving arrangement is provided for a measuring instrument having a movable element which is movable relative to a measuring instrument body. Measurement of an object to be measured is carried out through movement of the movable element. A driving and guide device is mounted on the measuring instrument body, and includes a driving cylinder having a piston received therein for axial movement. The movable element is moved in synchronism with the axial movement of the piston. A hydraulic fluid control device is arranged at a location remote from the measuring instrument body, for supplying hydraulic fluid to the driving cylinder of the driving and guide device to cause the axial movement of the piston of the driving cylinder.

Abstract: A detecting device for detecting fluctuation of an arm, to which a stylus is attached, comprises a linear guide installed to an arm supporting member and for guiding vertical or horizontal linear movement, a scale supporting member so installed to the linear guide as to be linearly movable, a jointing mechanism for converting circular arc movement caused by fluctuation of the arm to linear movement of the scale supporting member guided with the linear guide, the jointing mechanism having a jointing pin inserted between a projection integrally formed with the arm at a position of a given distance from an axis supporting part of the arm and the scale supporting member, and a displacement detecting device composed of a scale installed to the scale supporting member for detecting displacement by the linear movement.