Patents by Inventor Attilia Figini

Attilia Figini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF
    Publication number: 20220162155
    Abstract: Disclosed herein are forms of L-ornithine phenyl acetate and methods of making the same. A crystalline form may, in some embodiments, be Forms I, II, III and V, or mixtures thereof. The crystalline forms may be formulated for treating subjects with liver disorders, such as hepatic encephalopathy. Accordingly, some embodiments include formulations and methods of administering L-ornithine phenyl acetate.
    Type: Application
    Filed: November 1, 2021
    Publication date: May 26, 2022
    Inventors: Keith Anderson, Jim Behling, Christine Henderson Dougan, Stephen William Watt, Peter Manini, Attilia Figini
  • L-ornithine phenyl acetate and methods of making thereof
    Patent number: 11161802
    Abstract: Disclosed herein are forms of L-ornithine phenyl acetate and methods of making the same. A crystalline form may, in some embodiments, be Forms I, II, III and V, or mixtures thereof. The crystalline forms may be formulated for treating subjects with liver disorders, such as hepatic encephalopathy. Accordingly, some embodiments include formulations and methods of administering L-ornithine phenyl acetate.
    Type: Grant
    Filed: January 31, 2020
    Date of Patent: November 2, 2021
    Assignee: Ocera Therapeutics, Inc.
    Inventors: Keith Anderson, Jim Behling, Christine Henderson Dougan, Stephen William Watt, Peter Manini, Attilia Figini
  • Methods of producing molindone and its salts
    Patent number: 11117862
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Grant
    Filed: April 30, 2020
    Date of Patent: September 14, 2021
    Assignee: Supernus Pharmaceuticals, Inc.
    Inventors: Martin Hanbauer, Zarghun Nazir, Peter Hildebrand, Attilia Figini, Likan Liang, Tiziano Fumagalli
  • Crystalline platinum-based compounds
    Patent number: 10800801
    Abstract: The present disclosure relates to pharmaceutical sciences and chemical sciences. In particular, the present disclosure provides crystalline platinum-based compound IO-125, compositions and formulations comprising the same, along with method of preparing said crystalline compound, and uses thereof.
    Type: Grant
    Filed: May 18, 2017
    Date of Patent: October 13, 2020
    Assignee: AKAMARA THERAPEUTICS, INC.
    Inventors: Sarkar Arindam, Gavin Pringle, Jonathan Loughrey, Saurabh Chitre, Hayley Reece, Attilia Figini, Ivan Ruggiero
  • METHODS OF PRODUCING MOLINDONE AND ITS SALTS
    Publication number: 20200262789
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Application
    Filed: April 30, 2020
    Publication date: August 20, 2020
    Applicant: Supernus Pharmaceuticals, Inc.
    Inventors: Martin Hanbauer, Zarghun Nazir, Peter Hildebrand, Attilia Figini, Likan Liang, Tiziano Fumagalli
  • L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF
    Publication number: 20200239406
    Abstract: Disclosed herein are forms of L-ornithine phenyl acetate and methods of making the same. A crystalline form may, in some embodiments, be Forms I, II, III and V, or mixtures thereof. The crystalline forms may be formulated for treating subjects with liver disorders, such as hepatic encephalopathy. Accordingly, some embodiments include formulations and methods of administering L-ornithine phenyl acetate.
    Type: Application
    Filed: January 31, 2020
    Publication date: July 30, 2020
    Inventors: Keith Anderson, Jim Behling, Christine Henderson Dougan, Stephen William Watt, Peter Manini, Attilia Figini
  • Methods of producing molindone and its salts
    Patent number: 10676432
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: June 9, 2020
    Assignee: Supernus Pharmaceuticals, Inc.
    Inventors: Martin Hanbauer, Zarghun Nazir, Peter Hildebrand, Attilia Figini, Likan Liang, Tiziano Fumagalli
  • L-ornithine phenyl acetate and methods of making thereof
    Patent number: 10550069
    Abstract: Disclosed herein are forms of L-ornithine phenyl acetate and methods of making the same. A crystalline form may, in some embodiments, be Forms I, II, III and V, or mixtures thereof. The crystalline forms may be formulated for treating subjects with liver disorders, such as hepatic encephalopathy. Accordingly, some embodiments include formulations and methods of administering L-ornithine phenyl acetate.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: February 4, 2020
    Assignee: Ocera Therapeutics, Inc.
    Inventors: Keith E. Anderson, Jim Behling, Christine Henderson Dougan, Stephen William Watt, Peter Manini, Attilia Figini
  • CRYSTALLINE PLATINUM-BASED COMPOUNDS
    Publication number: 20190345180
    Abstract: The present disclosure relates to pharmaceutical sciences and chemical sciences. In particular, the present disclosure provides crystalline platinum-based compound IO-125, compositions and formulations comprising the same, along with method of preparing said crystalline compound, and uses thereof.
    Type: Application
    Filed: May 18, 2017
    Publication date: November 14, 2019
    Inventors: Sarkar ARINDAM, Gavin PRINGLE, Jonathan LOUGHREY, Saurabh CHITRE, Hayley REECE, Attilia FIGINI, Ivan RUGGIERO
  • METHODS OF PRODUCING MOLINDONE AND ITS SALTS
    Publication number: 20190218179
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Application
    Filed: August 21, 2018
    Publication date: July 18, 2019
    Applicant: Supernus Pharmaceuticals, Inc.
    Inventors: Martin HANBAUER, Zarghun NAZIR, Peter HILDEBRAND, Attilia FIGINI, Likan LIANG, Tiziano FUMAGALLI
  • L-ornithine phenyl acetate and methods of making thereof
    Patent number: 10173964
    Abstract: Disclosed herein are forms of L-ornithine phenyl acetate and methods of making the same. A crystalline form may, in some embodiments, be Forms I, II, III and V, or mixtures thereof. The crystalline forms may be formulated for treating subjects with liver disorders, such as hepatic encephalopathy. Accordingly, some embodiments include formulations and methods of administering L-ornithine phenyl acetate.
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: January 8, 2019
    Assignee: Ocera Therapeutics, Inc.
    Inventors: Keith E. Anderson, Jim Behling, Christine Henderson Dougan, Stephen William Watt, Peter Manini, Attilia Figini
  • L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF
    Publication number: 20180319736
    Abstract: Disclosed herein are forms of L-ornithine phenyl acetate and methods of making the same. A crystalline form may, in some embodiments, be Forms I, II, III and V, or mixtures thereof. The crystalline forms may be formulated for treating subjects with liver disorders, such as hepatic encephalopathy. Accordingly, some embodiments include formulations and methods of administering L-ornithine phenyl acetate.
    Type: Application
    Filed: July 17, 2018
    Publication date: November 8, 2018
    Inventors: Keith E. Anderson, Jim Behling, Christine Henderson Dougan, Stephen William Watt, Peter Manini, Attilia Figini
  • Methods of producing molindone and its salts
    Patent number: 10081595
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Grant
    Filed: October 3, 2017
    Date of Patent: September 25, 2018
    Assignee: Supernus Pharmaceuticals, Inc.
    Inventors: Martin Hanbauer, Zarghun Nazir, Peter Hildebrand, Attilia Figini, Likan Liang, Tiziano Fumagalli
  • L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF
    Publication number: 20180044281
    Abstract: Disclosed herein are forms of L-ornithine phenyl acetate and methods of making the same. A crystalline form may, in some embodiments, be Forms I, II, III and V, or mixtures thereof. The crystalline forms may be formulated for treating subjects with liver disorders, such as hepatic encephalopathy. Accordingly, some embodiments include formulations and methods of administering L-ornithine phenyl acetate.
    Type: Application
    Filed: March 24, 2017
    Publication date: February 15, 2018
    Inventors: Keith E. Anderson, Jim Behling, Christine Henderson Dougan, Stephen William Watt, Peter Manini, Attilia Figini
  • METHODS OF PRODUCING MOLINDONE AND ITS SALTS
    Publication number: 20180029982
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Application
    Filed: October 3, 2017
    Publication date: February 1, 2018
    Applicant: Supernus Pharmaceuticals, Inc.
    Inventors: Martin HANBAUER, Zarghun NAZIR, Peter HILDEBRAND, Attilia FIGINI, Likan LIANG, Tiziano FUMAGALLI
  • Methods of producing molindone and its salts
    Patent number: 9802893
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: October 31, 2017
    Assignee: Supernus Pharmaceuticals, Inc.
    Inventors: Martin Hanbauer, Zarghun Nazir, Peter Hildebrand, Attilia Figini, Likan Liang, Tiziano Fumagalli
  • METHODS OF PRODUCING MOLINDONE AND ITS SALTS
    Publication number: 20170101377
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Application
    Filed: November 30, 2016
    Publication date: April 13, 2017
    Applicant: Supernus Pharmaceuticals, Inc.
    Inventors: Martin HANBAUER, Zarghun NAZIR, Peter HILDEBRAND, Attilia FIGINI, Likan LIANG, Tiziano FUMAGALLI
  • L-ornithine phenyl acetate and methods of making thereof
    Patent number: 9604909
    Abstract: Disclosed herein are forms of L-ornithine phenyl acetate and methods of making the same. A crystalline form may, in some embodiments, be Forms I, II, III and V, or mixtures thereof. The crystalline forms may be formulated for treating subjects with liver disorders, such as hepatic encephalopathy. Accordingly, some embodiments include formulations and methods of administering L-ornithine phenyl acetate.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: March 28, 2017
    Assignee: Ocera Therapeutics, Inc.
    Inventors: Keith Anderson, Jim Behling, Christine Henderson Dougan, Stephen William Watt, Peter Manini, Attilia Figini
  • Methods of producing molindone and its salts
    Patent number: 9562011
    Abstract: The present invention is directed towards novel methods of synthesis of molindone, synthesis of the intermediates of molindone, and high-purity compositions of molindone. In particular, the invention relates to the methods of synthesis of molindone through the Mannich reaction.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: February 7, 2017
    Assignee: Supernus Pharmaceuticals, Inc.
    Inventors: Martin Hanbauer, Zarghun Nazir, Peter Hildebrand, Attilia Figini, Likan Liang, Tiziano Fumagalli
  • Methods of making L-ornithine phenyl acetate
    Patent number: 9260379
    Abstract: Disclosed herein are processes for making L-ornithine phenyl acetate. The process may include, for example, intermixing a halide salt of L-ornithine with silver phenyl acetate. The process may also include forming a phenyl acetate salt in situ. The present application also relates to various compositions obtained from these processes, including crystalline forms.
    Type: Grant
    Filed: January 21, 2015
    Date of Patent: February 16, 2016
    Assignee: Ocera Therapeutics, Inc.
    Inventors: Keith E. Anderson, Jim Behling, Christine Henderson Dougan, Stephen William Watt, Peter Manini, Attilia Figini