Patents by Inventor Aude Bernardin

Aude Bernardin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8652360
    Abstract: The present invention aims to provide a method of use for surface-modifying a semiconductor nanocrystal comprising at least the steps consisting in having a semiconductor nanocrystal, the organic coating layer of which is provided, at the outer surface of the nanocrystal, with at least one reactive group G1 that reacts according to a cycloaddition reaction of click chemistry type; and bringing said nanocrystal together with an adjoining material provided at the surface with at least one G2 group complementary to the G1 group with respect to said click chemistry reaction, under conditions favorable to the interaction of said G1 and G2 groups, characterized in that said G1 and G2 groups are respectively an azide and a strained cycloalkynyl radical, or vice versa.
    Type: Grant
    Filed: September 8, 2009
    Date of Patent: February 18, 2014
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Isabelle Texier-Nogues, Aude Bernardin
  • Patent number: 8653291
    Abstract: The invention relates to the use of disubstituted alkynes for the functionalisation of the surface of a substrate consisting of a semi-conductor material, with molecules of interest. According to the invention, a compound of formula A-(E1)n1-F1 is used, wherein A is a linear or cyclic disubstituted alkyne, E1 is an alkyl chain and n2 is 0 or 1, and F1 is a reactive group that can react with the reactive group F2 of a compound of formula F2-(E2)n2-X wherein E2 is an alkyl chain and X is a group having properties of interest. The invention is especially applicable to the field of molecular biology or biotechnology.
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: February 18, 2014
    Assignee: Commissariat a l'Energie Atomique et aux Energies Alternatives
    Inventors: Guillaume Delapierre, Regis Barattin, Aude Bernardin, Isabelle Texier-Nogues
  • Patent number: 8592619
    Abstract: The invention relates to compounds comprising a cycloalkyne or heterocycloalkyne group and a redox group. Said compounds are of general formula (I) wherein Z is a cycloalkyne or heterocycloalkyne with at least 8 links, optionally substituted by a halogen atom or a linear or branched C1 to C5 alkyl, A is an organic structure having oxidation-reduction properties, and B is an organic link between the cycloalkyne or heterocycloalkyne cycle and the organic structure A. The invention is especially applicable to the field of molecular electronics.
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: November 26, 2013
    Assignee: Commissariat a L'Energie Atomique et aux Enerigies Alternatives
    Inventors: Guillaume Delapierre, Regis Barattin, Aude Bernardin, Isabelle Texier-Nogues
  • Patent number: 8546598
    Abstract: The invention relates to a silane compound including a cycloalkyne functionality, to a method for functionalising a solid substrate, and to the solid substrate thus produced. The silane compound of the invention corresponds to the formula X-E-A-Z where X is a silyl group, E is an organic spacer group, A is a single bond or a —CONH—, —NHCO—, —OCH2CONH—, —NHCOCH2O—, —O— or —S— group, and Z is a cycloalkyne or heterocycloalkyne with at least 8 members. The invention is particularly suitable for use in the field of medicine.
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: October 1, 2013
    Assignee: Commissariat a l'Energie Atomique et aux Energies Alternatives
    Inventors: Aude Bernardin, Guillaume Delapierre, Antoine Hoang, Isabelle Texier-Nogues
  • Patent number: 8541604
    Abstract: The present invention is targeted at a novel coupling method of 1,3-dipolar cycloaddition type which is of particular use for the functionalization of biological molecules, such as, for example, proteins, enzymes or nucleic acids, insofar as it can be carried out in an aqueous medium and at ambient temperature.
    Type: Grant
    Filed: October 15, 2010
    Date of Patent: September 24, 2013
    Assignee: Commissariat a l'Energie Atomique et aux Energies Alternatives
    Inventors: Aude Bernardin, David Bonnaffe, Isabelle Texier-Nogues
  • Publication number: 20120095203
    Abstract: The invention relates to a silane compound including a cycloalkyne functionality, to a method for functionalising a solid substrate, and to the solid substrate thus produced. The silane compound of the invention corresponds to the formula X-E-A-Z where X is a silyl group, E is an organic spacer group, A is a single bond or a —CONH—, —NHCO—, —OCH2CONH—, —NHCOCH2O—, —0— or —S— group, and Z is a cycloalkyne or heterocycloalkyne with at least 8 members. The invention is particularly suitable for use in the field of medicine.
    Type: Application
    Filed: March 16, 2010
    Publication date: April 19, 2012
    Applicant: Commissariat A L'Energie Atomique Et Aux Ene Alt
    Inventors: Aude Bernardin, Guillaume Delapierre, Antoine Hoang, Isabelle Texier-Nogues
  • Publication number: 20120095247
    Abstract: The invention relates to the use of disubstituted alkynes for the functionalisation of the surface of a substrate consisting of a semi-conductor material, with molecules of interest. According to the invention, a compound of formula A-(E1)n1-F1 is used, wherein A is a linear or cyclic disubstituted alkyne, E1 is an alkyl chain and n2 is 0 or 1, and F1 is a reactive group that can react with the reactive group F2 of a compound of formula F2-(E2)n2-X wherein E2 is an alkyl chain and X is a group having properties of interest. The invention is especially applicable to the field of molecular biology or biotechnology.
    Type: Application
    Filed: March 16, 2010
    Publication date: April 19, 2012
    Applicant: COMMISSARIAT A L'ENERGIE AUTOMIQUE ET AUX ENE ALT
    Inventors: Guillaume Delapierre, Regis Barattin, Aude Bernardin, Isabelle Texier-Nogues
  • Publication number: 20120037871
    Abstract: The invention relates to compounds comprising a cycloalkyne or heterocycloalkyne group and a redox group. Said compounds are of general formula (I) wherein Z is a cycloalkyne or heterocycloalkyne with at least 8 links, optionally substituted by a halogen atom or a linear or branched C1 to C5 alkyl, A is an organic structure having oxidation-reduction properties, and B is an organic link between the cycloalkyne or heterocycloalkyne cycle and the organic structure A. The invention is especially applicable to the field of molecular electronics.
    Type: Application
    Filed: March 16, 2010
    Publication date: February 16, 2012
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Guillaume Delapierre, Regis Barattin, Aude Bernardin, Isabelle Texier-Nogues
  • Publication number: 20110118484
    Abstract: The present invention is targeted at a novel coupling method of 1,3-dipolar cycloaddition type which is of particular use for the functionalization of biological molecules, such as, for example, proteins, enzymes or nucleic acids, insofar as it can be carried out in an aqueous medium and at ambient temperature.
    Type: Application
    Filed: October 15, 2010
    Publication date: May 19, 2011
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Aude Bernardin, David Bonnaffe, Isabelle Texier-Nogues
  • Publication number: 20100200813
    Abstract: The present invention aims to provide a method of use for surface-modifying a semiconductor nanocrystal comprising at least the steps consisting in having a semiconductor nanocrystal, the organic coating layer of which is provided, at the outer surface of the nanocrystal, with at least one reactive group G1 that reacts according to a cycloaddition reaction of click chemistry type; and bringing said nanocrystal together with an adjoining material provided at the surface with at least one G2 group complementary to the G1 group with respect to said click chemistry reaction, under conditions favourable to the interaction of said G1 and G2 groups, characterized in that said G1 and G2 groups are respectively an azide and a strained cycloalkynyl radical, or vice versa.
    Type: Application
    Filed: September 8, 2009
    Publication date: August 12, 2010
    Applicant: COMMISSARIAT A L' ENERGIE ATOMIQUE
    Inventors: Isabelle Texier-Nogues, Aude Bernardin