Patents by Inventor Augustine Tobi Osuma

Augustine Tobi Osuma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prodrugs of amino acids with affinity for the ?2?-protein
    Patent number: 7491835
    Abstract: This invention relates to prodrugs of certain amino acids that bind to the alpha-2-delta (?2?) subunit of a calcium channel. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders.
    Type: Grant
    Filed: September 21, 2004
    Date of Patent: February 17, 2009
    Assignee: Pfizer Inc
    Inventors: Sean D. Donevan, Augustine Tobi Osuma, Andrew J. Thorpe, David Juergen Wustrow
  • Amino acids with affinity for the ?2?-protein
    Patent number: 7388023
    Abstract: Certain ?-amino acids that bind to the alpha-2-delta (?2?) subunit of a calcium channel are disclosed. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders. Also disclosed are methods of making the ?-amino acids.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: June 17, 2008
    Assignee: Warner-Lambert Company LLC
    Inventors: Peter Garth Blazecka, Joseph Richard Bozelak, Norman Lloyd Colbry, Timothy Thomas Curran, Annise Paige Goodman, Kevin E. Henegar, Garrett Hoge, Paul D. Johnson, Augustine Tobi Osuma, Mark Stephen Plummer, Jacob Bradley Schwarz, Derek Clinton Vrieze, Ji Zhang
  • Process for the synthesis of N-acyl-2-amino-4-alkoxy-5-nitrobenzoic acids
    Patent number: 7294740
    Abstract: The invention claimed herein provides a process to oxidize N-(5-alkoxy-2-methyl-4-nitrophenyl)acetamides to N-acyl-2-amino-4-alkoxy-5-nitrobenzoic acids using potassium permanganate in the presence of magnesium sulfate in aqueous sulfolane or aqueous pyridine.
    Type: Grant
    Filed: May 18, 2007
    Date of Patent: November 13, 2007
    Assignee: Wyeth
    Inventors: Scott Mason Duncan, Augustine Tobi Osuma, Sylvain Daigneault, Michel Bernatchez
  • Process for the synthesis of N-nacyl-2-amino-4-alkoxy-5-nitrobenzoic acids
    Patent number: 7227037
    Abstract: The invention claimed herein provides a process to oxidize N-(5-alkoxy-2-methyl-4-nitrophenyl)acetamides to N-acyl-2-amino-4-alkoxy-5-nitrobenzoic acids using potassium permanganate in the presence of magnesium sulfate in aqueous sulfolane or aqueous pyridine.
    Type: Grant
    Filed: February 5, 2003
    Date of Patent: June 5, 2007
    Assignee: Wyeth
    Inventors: Scott Mason Duncan, Augustine Tobi Osuma, Sylvain Daigneault, Michel Bernatchez
  • Amino acids with affinity for the ?2?-protein
    Patent number: 7179934
    Abstract: Certain ?-amino acids that bind to the alpha-2-delta (?2?) subunit of a calcium channel are disclosed. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders. Also disclosed are methods of making the ?-amino acids.
    Type: Grant
    Filed: September 24, 2004
    Date of Patent: February 20, 2007
    Assignee: Warner-Lambert Company LLC
    Inventors: Peter Garth Blazecka, Joseph Richard Bozelak, Norman Lloyd Colbry, Timothy Thomas Curran, Annise Paige Goodman, Kevin E. Henegar, Garrett Hoge, Paul D. Johnson, Augustine Tobi Osuma, Mark Stephen Plummer, Jacob Bradley Schwarz, Derek Clinton Vrieze, Ji Zhang
  • Mono-and disubstituted 3-propyl gamma-aminobutyric acids
    Publication number: 20040063789
    Abstract: The instant invention is a series of novel mono- and disubstituted 3-propyl gamma aminobutyric acids of Formula I 1
    Type: Application
    Filed: September 29, 2003
    Publication date: April 1, 2004
    Inventors: Thomas Richard Belliotti, Justin Stephen Bryans, Ihoezo Victor Ekhato, Augustine Tobi Osuma, Robert Michael Schelkun, Jacob Bradley Schwarz, Andrew John Thorpe, Lawrence David Wise, David Juergen Wustrow, Po-Wai Yuen
  • Mono-and disubstituted 3-propyl gamma-aminobutyric acids
    Patent number: 6642398
    Abstract: The instant invention is a series of novel mono- and disubstituted 3-propyl gamma aminobutyric acids of Formula I The compounds are useful as therapeutic agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, arthritis, sleep disorders, IBS, and gastric damage. Methods of preparing the compounds and useful intermediates are also part of the invention.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: November 4, 2003
    Assignee: Warner-Lambert Company
    Inventors: Thomas Richard Belliotti, Justin Stephen Bryans, Ihoezo Victor Ekhato, Augustine Tobi Osuma, Robert Michael Schelkun, Jacob Bradley Schwarz, Andrew John Thorpe, Lawrence David Wise, David Juergen Wustrow, Po-Wai Yuen
  • Mono-and disubstituted 3-propyl gamma-aminobutyric acids
    Publication number: 20030181523
    Abstract: The instant invention is a series of novel mono- and disubstituted 3-propyl gamma aminobutyric acids of Formula I 1
    Type: Application
    Filed: December 20, 2002
    Publication date: September 25, 2003
    Inventors: Thomas Richard Belliotti, Justin Stephen Bryans, Ihoezo Victor Ekhato, Augustine Tobi Osuma, Robert Michael Schelkun, Jacob Bradley Schwarz, Andrew John Thorpe, Lawrence David Wise, David Juergen Wustrow, Po-Wai Yuen