Abstract: A kit-of-parts for visualizing by a magnetic resonance imaging (MRI) technique including a functional magnetic resonance imaging (fMRI) technique, regions of a central nervous system of a patient having an implanted active implantable medical device (AIMD) is provided. The kit-of-parts is provided and includes: the AIMD, which can be used exposed to the electromagnetic conditions for MR-images acquisition, an external processing unit for controlling the AIMD, an optical communication lead for establishing a two-way optical communication between the AIMD and an external communication unit which is controlled by the external processing unit. A patient having an implanted AIMD can be treated in a conventional MR-device for imaging, e.g., a brain region. The other elements of the kit-of-parts allow controlling the functions of the AIMD and following any effects of a stimulation on the brain region thus imaged.

Abstract: A kit-of-parts for visualizing by a magnetic resonance imaging (MRI) technique including a functional magnetic resonance imaging (fMRI) technique, regions of a central nervous system of a patient having an implanted active implantable medical device (AIMD) is provided. The kit-of-parts is provided and includes: the AIMD, which can be used exposed to the electromagnetic conditions for MR-images acquisition, an external processing unit for controlling the AIMD, an optical communication lead for establishing a two-way optical communication between the AIMD and an external communication unit which is controlled by the external processing unit. A patient having an implanted AIMD can be treated in a conventional MR-device for imaging, e.g., a brain region. The other elements of the kit-of-parts allow controlling the functions of the AIMD and following any effects of a stimulation on the brain region thus imaged.

Abstract: An active implantable medical device includes an encapsulation (1) defining an inner space sealingly separated from an outer environment by walls transparent to a given wavelength range. The walls have a first main wall (1a) and a second main wall (1b) facing one another and separated from one another by an inner height (Hi) of the inner space. An encapsulation includes a housing formed by a first component (2) and a second component (3) both made of a single material and hermetically joined to one another along a single interface (23) to define the inner space hermetically sealed by the walls from the outer environment. An inner space contains an electronic, and facing a wall of the encapsulation. wherein joining of the first component and second components (2, 3) is carried out by welding without addition of a third material, the inner space has a volume (Vi) of at least 2 cm3.

Abstract: An implantable cuff electrode and/or optrode adapted to encircle a substantially cylindrical body tissue, and selected among self sizing cuff and a split cylinder cuff, is provided and includes a support sheet rolled about a longitudinal axis to form a cuff electrode/optrode, with an inner handling flap provided that includes a coupled end belonging to a coupled portion which is fixed to a portion of the outer surface of the support sheet which is adjacent to the inner edge, and a free end, opposite the coupled end belonging to a free portion adjacent to the coupled portion and separated therefrom by a transition line, said free portion being loose from the outer surface of the support sheet.

Abstract: A polymer optical fibre (POF) (30) for transmitting light of wavelength, ?i, between two separate elements of an active implantable medical device (AIMD), includes a core (31) which is cylindrical and made of a cyclic olefin polymer (COP) or copolymer (COC), having a core refractive index at the wavelength, ?i, n_core, A cladding (32) which has a cladding refractive index at the wavelength, ?i, n_clad<n_core, and which is made of a cladding copolymer including monomers of tetrafluoroethylene, hexafluoropropylene and vinylidene fluoride. The cladding being itself enclosed in a coating (33) which is made of a coating polymer formed of one of the monomers of the cladding copolymer. The POF has a numerical aperture, NA, at the wavelength, ?i, of at least 0.5.

Abstract: An active implantable medical device includes an encapsulation (1) defining an inner space sealingly separated from an outer environment by walls transparent to a given wavelength range. The walls have a first main wall (1a) and a second main wall (1b) facing one another and separated from one another by an inner height (Hi) of the inner space. An encapsulation includes a housing formed by a first component (2) and a second component (3) both made of a single material and hermetically joined to one another along a single interface (23) to define the inner space hermetically sealed by the walls from the outer environment. An inner space contains an electronic, and facing a wall of the encapsulation. wherein joining of the first component and second components (2, 3) is carried out by welding without addition of a third material, the inner space has a volume (Vi) of at least 2 cm3.

Abstract: An optical fibres connector for an optoelectronic active implantable medical device (AIMD) for implantation in a living body is provided. The optical fibres connector includes a male component (M) coupled to a first set of optical fibres, a female component (F) coupled to a second set of optical fibres or optical elements, and a coupling component (C) for reversibly locking the male and female components in a coupled position. The optical fibres or optical elements are in perfect alignment. The coupling component includes a fixed element (40f) and a rotatable element (40r) all optical fibres (41f) and optical elements of the connector remaining static upon rotation of the rotatable element, reversibly locking the male and female components in the coupled position is achieved by rotating the rotatable element with respect to the fixed element.

Abstract: An optical fibres connector for an optoelectronic active implantable medical device (AIMD) for implantation in a living body is provided. The optical fibres connector includes a male component (M) coupled to a first set of optical fibres, a female component (F) coupled to a second set of optical fibres or optical elements, and a coupling component (C) for reversibly locking the male and female components in a coupled position The optical fibres or optical elements are in perfect alignment. The coupling component includes a fixed element (40f) and a rotatable element (40r) all optical fibres (41f) and optical elements of the connector remaining static upon rotation of the rotatable element, reversibly locking the male and female components in the coupled position is achieved by rotating the rotatable element with respect to the fixed element.