Abstract: The present disclosure is directed to antibodies or antigen-binding portions thereof that specifically bind human CCR8, polynucleotides and vectors encoding the same, and pharmaceutical compositions comprising the same. Some aspects of the disclosure are directed to methods of treating a disease or condition comprising administering the anti-CCR8 antibody to a subject in need thereof.

Abstract: A plugging resistant, highly stable free jet burner and method which provide Ultra-Low NOx emissions for any fuel using angular ejection, large ejection ports, auxiliary burner tips, and wide tip-to-tip spacing, and which also permit the use of a high-hydrogen or 100% hydrogen fuel to reduce or substantially eliminate carbon dioxide emissions.

Abstract: A system includes a processor configured to determine an applicable pre-defined vehicle system state set, defining preferred vehicle system states when a driver is away from a vehicle. The processor is also configured to determine a driver exit-event while a vehicle state in the state set varies from a preferred setting and notify a driver mobile device of the variance, responsive to the exit event.

Abstract: A vehicle system including a vehicle component and a controller is provided. The controller may selectively activate the vehicle component and communicate with a mobile unit including an interface. The controller may be programmed to interact with the mobile unit upon detection by accessing vehicle sleep mode instructions preprogrammed by a user via the interface in which the controller activates the vehicle component according to an escalation sequence schedule to disengage a vehicle sleep mode. The system may further include a sensor in communication with the vehicle component and the controller. The controller may be further programed to activate the vehicle component according to the escalation sequence schedule based on receipt of a signal from a sensor indicating a passenger is asleep.

Abstract: A system includes a processor configured to determine an applicable pre-defined vehicle system state set, defining preferred vehicle system states when a driver is away from a vehicle. The processor is also configured to determine a driver exit-event while a vehicle state in the state set varies from a preferred setting and notify a driver mobile device of the variance, responsive to the exit event.

Abstract: A system includes a processor configured to determine an applicable pre-defined vehicle system state set, defining preferred vehicle system states when a driver is away from a vehicle. The processor is also configured to determine a driver exit-event while a vehicle state in the state set varies from a preferred setting and notify a driver mobile device of the variance, responsive to the exit event.

Abstract: A vehicle system including a vehicle component and a controller is provided. The controller may selectively activate the vehicle component and communicate with a mobile unit including an interface. The controller may be programmed to interact with the mobile unit upon detection by accessing vehicle sleep mode instructions preprogrammed by a user via the interface in which the controller activates the vehicle component according to an escalation sequence schedule to disengage a vehicle sleep mode. The system may further include a sensor in communication with the vehicle component and the controller. The controller may be further programed to activate the vehicle component according to the escalation sequence schedule based on receipt of a signal from a sensor indicating a passenger is asleep.

Abstract: A system includes a processor configured to determine an applicable pre-defined vehicle system state set, defining preferred vehicle system states when a driver is away from a vehicle. The processor is also configured to determine a driver exit-event while a vehicle state in the state set varies from a preferred setting and notify a driver mobile device of the variance, responsive to the exit event.