Patents by Inventor Austin L. Bailey

Austin L. Bailey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fusogenic liposomes
    Publication number: 20030125517
    Abstract: The present invention relates to liposomes and virosomes and, more particularly, to liposomal and virosomal delivery systems for transporting materials such as drugs, nucleic acids and proteins.
    Type: Application
    Filed: June 5, 2002
    Publication date: July 3, 2003
    Applicant: The University of British Columbia
    Inventors: Pieter R. Cullis, Lewis S.L. Choi, Myrna Monck, Austin L. Bailey
  • Fusogenic liposomes
    Patent number: 6417326
    Abstract: The present invention relates to liposomes and virosomes and, more particularly, to liposomal and virosomal delivery systems for transporting materials such as drugs, nucleic acids and proteins.
    Type: Grant
    Filed: April 10, 1997
    Date of Patent: July 9, 2002
    Assignee: The University of British Columbia
    Inventors: Pieter R. Cullis, Lewis S. L. Choi, Myrna Monck, Austin L. Bailey
  • Fusogenic lipsomes and methods for making and using same
    Patent number: 5552155
    Abstract: A liposome composition is provided which contains a liposome having: (i) an outermost lipid bilayer containing, in addition to a neutral, bilayer preferring lipid, a fusion-promoting effective amount of an ionizable lipid having a protonatable, cationic headgroup and an unsaturated acyl chain; and (ii) a compartment adjacent to the outermost lipid bilayer which contains an aqueous solution having a first pH. External to the liposome in the composition is an aqueous solution having a second pH. The first pH is less than the pK.sub.a of the ionizable lipid in the outermost lipid bilayer and the second pH is greater than the pK.sub.a of the ionizable lipid in the outermost lipid bilayer, such that there is a pH gradient across the outermost lipid bilayer and the ionizable lipid is accumulated in the inner monolayer of the outermost lipid bilayer in response to the gradient.
    Type: Grant
    Filed: August 15, 1994
    Date of Patent: September 3, 1996
    Assignee: The Liposome Company, Inc.
    Inventors: Austin L. Bailey, Pieter R. Cullis