Patents by Inventor Avi Eldar

Avi Eldar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11583579
    Abstract: The invention is directed to isolated Tilapia Lake Virus or TiLV, and isolated nucleic acids sequences and polypeptides thereof. The invention also relates to probes and primers, and to antibodies against antigens from TiLV, and use of these reagents for detecting the presence or absence of TiLV in an animal. The invention also relates to iRNAs which target nucleic acid sequences of TiLV. The invention is also related to immunogenic compositions, including antibodies and vaccines, for inducing an immune response against TiLV in an animal. The invention is also related to gene constructs and cells comprising TiLV and isolated nucleic acids sequences and polypeptides thereof for use in developing prophylactic and therapeutic agents.
    Type: Grant
    Filed: March 5, 2021
    Date of Patent: February 21, 2023
    Assignees: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, RAMOT AT TEL-AVIV UNIVERSITY LTD., KIMRON VETERINARY INSTITUTE
    Inventors: W. Ian Lipkin, Thomas Briese, Nischay Mishra, Eran Bacharach, Avi Eldar
  • Publication number: 20210205437
    Abstract: The invention is directed to isolated Tilapia Lake Virus or TiLV, and isolated nucleic acids sequences and polypeptides thereof. The invention also relates to probes and primers, and to antibodies against antigens from TiLV, and use of these reagents for detecting the presence or absence of TiLV in an animal. The invention also relates to iRNAs which target nucleic acid sequences of TiLV. The invention is also related to immunogenic compositions, including antibodies and vaccines, for inducing an immune response against TiLV in an animal. The invention is also related to gene constructs and cells comprising TiLV and isolated nucleic acids sequences and polypeptides thereof for use in developing prophylactic and therapeutic agents.
    Type: Application
    Filed: March 5, 2021
    Publication date: July 8, 2021
    Inventors: W. Ian LIPKIN, Thomas BRIESE, Nischay Mishra, Eran Bacharach, Avi Eldar
  • Patent number: 10973902
    Abstract: The invention is directed to isolated Tilapia Lake Virus or TiLV, and isolated nucleic acids sequences and polypeptides thereof. The invention also relates to probes and primers, and to antibodies against antigens from TiLV, and use of these reagents for detecting the presence or absence of TiLV in an animal. The invention also relates to iRNAs which target nucleic acid sequences of TiLV. The invention is also related to immunogenic compositions, including antibodies and vaccines, for inducing an immune response against TiLV in an animal. The invention is also related to gene constructs and cells comprising TiLV and isolated nucleic acids sequences and polypeptides thereof for use in developing prophylactic and therapeutic agents.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: April 13, 2021
    Assignees: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, RAMOT AT TEL-AVIV UNIVERSITY LTD., KIMRON VETERINARY INSTITUTE
    Inventors: W. Ian Lipkin, Thomas Briese, Nischay Mishra, Eran Bacharach, Avi Eldar
  • Publication number: 20200254084
    Abstract: The invention is directed to isolated Tilapia Lake Virus or TiLV, and isolated nucleic acids sequences and polypeptides thereof. The invention also relates to probes and primers, and to antibodies against antigens from TiLV, and use of these reagents for detecting the presence or absence of TiLV in an animal. The invention also relates to iRNAs which target nucleic acid sequences of TiLV. The invention is also related to immunogenic compositions, including antibodies and vaccines, for inducing an immune response against TiLV in an animal. The invention is also related to gene constructs and cells comprising TiLV and isolated nucleic acids sequences and polypeptides thereof for use in developing prophylactic and therapeutic agents.
    Type: Application
    Filed: February 6, 2020
    Publication date: August 13, 2020
    Inventors: W. Ian LIPKIN, Thomas BRIESE, Nischay Mishra, Eran Bacharach, Avi Eldar
  • Patent number: 10596249
    Abstract: The invention is directed to isolated Tilapia Lake Virus or TiLV, and isolated nucleic acids sequences and polypeptides thereof. The invention also relates to probes and primers, and to antibodies against antigens from TiLV, and use of these reagents for detecting the presence or absence of TiLV in an animal. The invention also relates to iRNAs which target nucleic acid sequences of TiLV. The invention is also related to immunogenic compositions, including antibodies and vaccines, for inducing an immune response against TiLV in an animal. The invention is also related to gene constructs and cells comprising TiLV and isolated nucleic acids sequences and polypeptides thereof for use in developing prophylactic and therapeutic agents.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: March 24, 2020
    Assignees: KIMRON VETERINARY INSTITUTE, THE TRUSTEES OF COLUMBIA UNIVERISTY IN THE CITY OF NEW YORK, RAMOT AT TEL-AVIV UNIVERISTY LTD.
    Inventors: W. Ian Lipkin, Thomas Briese, Nischay Mishra, Eran Bacharach, Avi Eldar
  • Patent number: 10537631
    Abstract: The present invention relates to vaccine compositions comprising attenuated strain of Tilapia Lake Virus (TiLV) for protecting tilapia fish against infection by (TiLV). The invention also relates to methods for using the vaccines to protect tilapines from TiLV-induced disease.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: January 21, 2020
    Assignees: The State of Israel, Ministry of Agriculture & Rural Developement, Kimron Veterinary Institute, Ramot At Tel-Aviv University Ltd.
    Inventors: Eran Bacharach, Avi Eldar
  • Publication number: 20190216914
    Abstract: The present invention relates to vaccine compositions comprising attenuated strain of Tilapia Lake Virus (TiLV) for protecting tilapia fish against infection by (TiLV). The invention also relates to methods for using the vaccines to protect tilapines from TiLV-induced disease.
    Type: Application
    Filed: August 13, 2018
    Publication date: July 18, 2019
    Inventors: Eran Bacharach, Avi Eldar
  • Patent number: 10183072
    Abstract: The invention is directed to isolated Tilapia Lake Virus or TiLV, and isolated nucleic acids sequences and polypeptides thereof. The invention also relates to probes and primers, and to antibodies against antigens from TiLV, and use of these reagents for detecting the presence or absence of TiLV in an animal. The invention also relates to iRNAs which target nucleic acid sequences of TiLV. The invention is also related to immunogenic compositions, including antibodies and vaccines, for inducing an immune response against TiLV in an animal. The invention is also related to gene constructs and cells comprising TiLV and isolated nucleic acids sequences and polypeptides thereof for use in developing prophylactic and therapeutic agents.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: January 22, 2019
    Assignees: KIMRON VETERINARY INSTITUTE, THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: W. Ian Lipkin, Thomas Briese, Nischay Mishra, Eran Bacharach, Avi Eldar
  • Publication number: 20180369360
    Abstract: The invention is directed to isolated Tilapia Lake Virus or TiLV, and isolated nucleic acids sequences and polypeptides thereof. The invention also relates to probes and primers, and to antibodies against antigens from TiLV, and use of these reagents for detecting the presence or absence of TiLV in an animal. The invention also relates to iRNAs which target nucleic acid sequences of TiLV. The invention is also related to immunogenic compositions, including antibodies and vaccines, for inducing an immune response against TiLV in an animal. The invention is also related to gene constructs and cells comprising TiLV and isolated nucleic acids sequences and polypeptides thereof for use in developing prophylactic and therapeutic agents.
    Type: Application
    Filed: August 23, 2018
    Publication date: December 27, 2018
    Inventors: W. Ian Lipkin, Thomas Briese, Nischay Mishra, Eran Bacharach, Avi Eldar
  • Patent number: 10071152
    Abstract: The present invention relates to vaccine compositions comprising attenuated strain of Tilapia Lake Virus (TiLV) for protecting tilapia fish against infection by (TiLV). The invention also relates to methods for using the vaccines to protect tilapines from TiLV-induced disease.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: September 11, 2018
    Assignees: Kimron Veterinary Institute, Ramot at Tel-Avin University Ltd.
    Inventors: Eran Bacharach, Avi Eldar
  • Publication number: 20180008692
    Abstract: The present invention relates to vaccine compositions comprising attenuated strain of Tilapia Lake Virus (TiLV) for protecting tilapia fish against infection by (TiLV). The invention also relates to methods for using the vaccines to protect tilapines from TiLV-induced disease.
    Type: Application
    Filed: July 10, 2017
    Publication date: January 11, 2018
    Inventors: Eran Bacharach, Avi Eldar
  • Publication number: 20170360918
    Abstract: The invention is directed to isolated Tilapia Lake Virus or TiLV, and isolated nucleic acids sequences and polypeptides thereof. The invention also relates to probes and primers, and to antibodies against antigens from TiLV, and use of these reagents for detecting the presence or absence of TiLV in an animal. The invention also relates to iRNAs which target nucleic acid sequences of TiLV. The invention is also related to immunogenic compositions, including antibodies and vaccines, for inducing an immune response against TiLV in an animal. The invention is also related to gene constructs and cells comprising TiLV and isolated nucleic acids sequences and polypeptides thereof for use in developing prophylactic and therapeutic agents.
    Type: Application
    Filed: December 15, 2015
    Publication date: December 21, 2017
    Inventors: W. Ian LIPKIN, Thomas BRIESE, Nischay Mishra, Eran Bacharach, Avi Eldar
  • Patent number: 9730998
    Abstract: The present invention relates to vaccine compositions comprising attenuated strain of Tilapia Lake Virus (TiLV) for protecting tilapia fish against infection by (TiLV). The invention also relates to methods for using the vaccines to protect tilapines from TiLV-induced disease.
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: August 15, 2017
    Assignees: The State of Israel, Ministry of Agriculture & Rural Development, Kimron Veterinary Institute, Ramot at Tel-Aviv University Ltd.
    Inventors: Eran Bacharach, Avi Eldar
  • Publication number: 20160354458
    Abstract: The present invention relates to vaccine compositions comprising attenuated strain of Tilapia Lake Virus (TiLV) for protecting tilapia fish against infection by (TiLV). The invention also relates to methods for using the vaccines to protect tilapines from TiLV-induced disease.
    Type: Application
    Filed: February 11, 2015
    Publication date: December 8, 2016
    Applicants: The State of Israel, Ministry of Agriculture & Rur al Development, Kimron Veterinary Institute, Ramot at Tel-Aviv University Ltd.
    Inventors: Eran Bacharach, Avi Eldar