Patents by Inventor Aviva Shiedlin

Aviva Shiedlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERMO-SENSITIVE BONE GROWTH COMPOSITIONS
    Publication number: 20180104180
    Abstract: A non-invasive injectable composition that contains type I collagen, an osteogenic growth factor (OSF), such as a bone morphogenetic protein and a reverse thermo-sensitive biodegradable polymer such as Poloxamer 407 in an aqueous vehicle. The formulation can be administered non-invasively, e.g., by injection, thus circumventing limitations of many currently marketed bone-inducing products. The injectable osteogenic formulation effectively induces bone formation at the desired locale. This injectable suspension could be used with bioresorbable bone mineral composites (e.g., Hydroxyapatite, Tri-calcium phosphate) and/or glycosaminolycans (e.g., Hyaluronic acid, Heparin sulfate) to mold as putty and/slab as bone graft substitute implants to induce new bone formation in fracture healing and spine fusion procedures.
    Type: Application
    Filed: May 23, 2017
    Publication date: April 19, 2018
    Inventors: Kuber T. Sampath, Michael Philbrook, Aviva Shiedlin, John M. McPherson
  • THERMO-SENSITIVE BONE GROWTH COMPOSITIONS
    Publication number: 20140271471
    Abstract: A non-invasive injectable composition that contains type I collagen, an osteogenic growth factor (OSF), such as a bone morphogenetic protein and a reverse thermo-sensitive biodegradable polymer such as Poloxamer 407 in an aqueous vehicle. The formulation can be administered non-invasively, e.g., by injection, thus circumventing limitations of many currently marketed bone-inducing products. The injectable osteogenic formulation effectively induces bone formation at the desired locale. This injectable suspension could be used with bioresorbable bone mineral composites (e.g., Hydroxyapatite, Tri-calcium phosphate) and/or glycosaminoglycans (e.g., Hyaluronic acid, Heparin sulfate) to mold as putty and/slab as bone graft substitute implants to induce new bone formation in fracture healing and spine fusion procedures.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: Genzyme Corporation
    Inventors: Kuber T. Sampath, Michael Philbrook, Aviva Shiedlin, John M. McPherson
  • Cartilage Repair
    Publication number: 20120088721
    Abstract: This invention relates to compositions, methods of preparation thereof, and use thereof for cartilage repair.
    Type: Application
    Filed: March 22, 2010
    Publication date: April 12, 2012
    Applicant: GENZYME CORPORATION
    Inventors: Aviva Shiedlin, Timothy J. Butler, Michael Philbrook, Peter K. Jarrett
  • Molecular weight reduction of polymer using irradiation treatment
    Publication number: 20020156146
    Abstract: Polymer compositions having reduced molecular weight prepared by a method which comprises subjecting a solid phase polymer to a dose of gamma irradiation sufficient to permit the desired molecular weight reduction to occur.
    Type: Application
    Filed: April 1, 2002
    Publication date: October 24, 2002
    Applicant: Genzyme Corporation
    Inventors: Robert J. Miller, Aviva Shiedlin
  • Molecular weight reduction of polymer using irradiation treatment
    Patent number: 6383344
    Abstract: A method for reducing the molecular weight of polymer comprises subjecting a solid phase polymer to a dose of gamma irradiation sufficient to permit the desired molecular weight reduction to occur.
    Type: Grant
    Filed: July 19, 2000
    Date of Patent: May 7, 2002
    Assignee: Genzyme Corporation
    Inventors: Robert J. Miller, Aviva Shiedlin