Patents by Inventor Ayako Nakamura
Ayako Nakamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11774340Abstract: For an easy calibration using calibration particles, provided is a measuring device to capture images of target objects. An image analyzer acquires multiple images obtained at a predetermined time interval, (a) specifies the mean-square displacement of a bright point of a calibration particle based on the displacement of the bright point of the calibration particle in the multiple images in a calibration mode, and (b) specifies the mean-square displacement of a bright point of the target particle based on the displacement of the bright point of the target particle in the multiple images in a measurement mode. A particle size analyzer (c) derives the particle size of the target particle from the mean-square displacement of the bright point of the target particle based on the mean-square displacement of the bright point of the calibration particle and the particle size of the calibration particle in an analysis mode.Type: GrantFiled: September 30, 2019Date of Patent: October 3, 2023Assignees: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, RION Co., Ltd., Kioxia CorporationInventors: Haruhisa Kato, Yusuke Matsuura, Ayako Nakamura, Kaoru Kondo, Takuya Tabuchi, Hiroshi Tomita, Hidekazu Hayashi
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Publication number: 20230149866Abstract: A wet atomization apparatus includes: a process-target fluid storing container for storing the process-target fluid; a syringe including a gasket configured to be slid on an inner peripheral wall of the syringe by a plunger; a thin tube having one end inserted in the process-target fluid storing container and another end connected to the syringe; and a control section that performs control of the plunger to move forward and backward. Under the control by the control section, an atomization process is performed at least once in which the plunger is moved backward to allow the process-target fluid in the process-target fluid storing container to flow into the syringe via the thin tube so as to be stored in the syringe and the plunger is moved forward to return the process-target fluid stored in the syringe into the process-target fluid storing container via the thin tube.Type: ApplicationFiled: March 25, 2021Publication date: May 18, 2023Inventors: Satoshi YOSHIDA, Satoru YOSHIDA, Haruhisa KATO, Ayako NAKAMURA
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Publication number: 20230025660Abstract: A vehicle includes a processor that includes hardware. When an own vehicle is connected to an external network via a communication mesh network created by vehicle-to-vehicle communication that takes place between multiple vehicles, the processor outputs connection information indicating that the own vehicle is connected to the external network as information that is able to be visually recognized from outside of the vehicle.Type: ApplicationFiled: May 9, 2022Publication date: January 26, 2023Inventors: Masayuki IMOTO, Jun MIYAGAWA, Yasue MANO, Ayako NAKAMURA, Naohiro SEO
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Publication number: 20220404826Abstract: An information collection device according to the present disclosure is an information collection device that causes a small unmanned aerial vehicle to fly from a departure point to a destination and collects information at the destination using the small unmanned aerial vehicle, and includes a control device that causes the small unmanned aerial vehicle to fly from the departure point to the destination by transmitting a control signal to the small unmanned aerial vehicle by wireless information communication via a vehicle when determination is made that the wireless information communication is able to be executed with the small unmanned aerial vehicle via the vehicle located between the departure point and the destination.Type: ApplicationFiled: April 18, 2022Publication date: December 22, 2022Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Masayuki Imoto, Jun Miyagawa, Yasue Mano, Ayako Nakamura, Naohiro Seo
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Patent number: 11439634Abstract: An object of the present invention is mainly to provide a medical skin external preparation that is suitable for treating superficial skin infections, in particular, superficial skin infections accompanied by blister or erosion, etc. For example, the present invention can provide a medical skin external preparation containing 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid and/or a pharmaceutically acceptable salt thereof as an active ingredient, and an alcohol and/or a fatty acid having 12 or more carbon atoms.Type: GrantFiled: November 30, 2017Date of Patent: September 13, 2022Assignee: Maruho Co., Ltd.Inventors: Tomoki Sakaguchi, Masumi Kawaguchi, Ayako Nakamura
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Patent number: 11415500Abstract: The purpose of the present invention is to provide a particulate observation device using light scattering, which includes a means for determining the three-dimensional position of a particle, and can measure an accurate particle size or impart various properties of same. The present invention is characterized by including a position determination means which captures, with an optical microscope, an image of light scattered from particles in a dispersion medium to which laser light is emitted, and determines a three-dimensional position of each particle from the obtained two dimensional image, wherein the position determination obtains two-dimensional coordinates along the two-dimensional image from luminescent point positions of the particles, and determines the depth position along a coordinate axis vertical to the two-dimensional image from the diameters of diffraction fringes of the luminescent points.Type: GrantFiled: August 30, 2019Date of Patent: August 16, 2022Assignee: National Institute of Advanced Industrial Science and TechnologyInventors: Haruhisa Kato, Yusuke Matsuura, Ayako Nakamura
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Publication number: 20220241250Abstract: What is aimed at is to provide a topical preparation that contains tacrolimus as an active pharmaceutical ingredient, has high stability and transdermal absorbability of the active pharmaceutical ingredient, is less irritating, and has a good feeling of use. The present invention relates to a liquid topical preparation that contains (i) tacrolimus, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate thereof, and (ii) at least one ketone, and that is substantially free of ethanol. It is preferable that the liquid topical preparation further contains at least one fatty acid ester and fluid paraffin, and is substantially free of water.Type: ApplicationFiled: July 24, 2019Publication date: August 4, 2022Inventors: Fuminori NARUMI, Ayako NAKAMURA, Satoko SUZUKI
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Publication number: 20220105237Abstract: It is an object of the present invention to provide a film-forming composition for skin (such as a film-type skin protectant or a film-type skin topical agent) that does not contain a lower monohydric alcohol such as ethanol or isopropanol, is excellent in quick-drying properties and water resistance, is less sticky, and is excellent in feeling of use. The present invention relates to a film-forming composition for skin which contains a specific acrylic polymer, a plasticizer and water and is substantially free of a lower monohydric alcohol such as ethanol or isopropanol. The composition of the present invention is extremely useful for treatment of chronic skin diseases (that is, skin diseases in which skin barrier function is deteriorated) represented by hand eczema, atopic dermatitis, and the like.Type: ApplicationFiled: February 3, 2020Publication date: April 7, 2022Inventors: Ayako NAKAMURA, Hiroki SAKIYAMA, Leila HAFSI, Naoya OTSUKA
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Patent number: 11280652Abstract: A measuring method enabling simple and accurate measurement of a flow velocity distribution in a flow field inside a flow passage of an optical cell and a particle size-measuring method using the measuring method are provided. Providing a tracer particle of a smaller size than wavelength ? of laser light into the flow passage and capturing a bright spot attributed to light scattering from tracer particles by camera, and obtaining the flow velocity distribution by the analysis unit by obtaining an amount of movement of each tracer particle from movement of the bright spot and correcting a Brownian motion component from a correlation between an average value of variations of the amount of movement and Brownian motion are performed.Type: GrantFiled: December 5, 2017Date of Patent: March 22, 2022Inventors: Haruhisa Kato, Yusuke Matsuura, Ayako Nakamura
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Publication number: 20210348999Abstract: For an easy calibration using calibration particles, provided is a measuring device to capture images of target objects. An image analyzer acquires multiple images obtained at a predetermined time interval, (a) specifies the mean-square displacement of a bright point of a calibration particle based on the displacement of the bright point of the calibration particle in the multiple images in a calibration mode, and (b) specifies the mean-square displacement of a bright point of the target particle based on the displacement of the bright point of the target particle in the multiple images in a measurement mode. A particle size analyzer (c) derives the particle size of the target particle from the mean-square displacement of the bright point of the target particle based on the mean-square displacement of the bright point of the calibration particle and the particle size of the calibration particle in an analysis mode.Type: ApplicationFiled: September 30, 2019Publication date: November 11, 2021Inventors: Haruhisa KATO, Yusuke MATSUURA, Ayako NAKAMURA, Kaoru KONDO, Takuya TABUCHI, Hiroshi TOMITA, Hidekazu HAYASHI
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Publication number: 20210055197Abstract: The purpose of the present invention is to provide a particulate observation device using light scattering, which includes a means for determining the three-dimensional position of a particle, and can measure an accurate particle size or impart various properties of same. The present invention is characterized by including a position determination means which captures, with an optical microscope, an image of light scattered from particles in a dispersion medium to which laser light is emitted, and determines a three-dimensional position of each particle from the obtained two dimensional image, wherein the position determination obtains two-dimensional coordinates along the two-dimensional image from luminescent point positions of the particles, and determines the depth position along a coordinate axis vertical to the two-dimensional image from the diameters of diffraction fringes of the luminescent points.Type: ApplicationFiled: August 30, 2019Publication date: February 25, 2021Applicant: National Institute of Advanced Industrial Science and TechnologyInventors: Haruhisa Kato, Yusuke Matsuura, Ayako Nakamura
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Publication number: 20200064169Abstract: A measuring method enabling simple and accurate measurement of a flow velocity distribution in a flow field inside a flow passage of an optical cell and a particle size-measuring method using the measuring method are provided.Type: ApplicationFiled: December 5, 2017Publication date: February 27, 2020Inventors: Haruhisa KATO, Yusuke MATSUURA, Ayako NAKAMURA
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Publication number: 20190383726Abstract: A flow cell for optical measurement capable of accurately measuring light emitted from particles, which is caused by a laser light provided into the flow path. A flow path block having a substantially cuboid shape and made of a transparent material is detachably interposed between a pair of a fluid medium inlet block and a fluid medium outlet block, and a light absorbing surface of the fluid medium inlet block and a light absorbing surface of the fluid medium outlet block are pressed against both end surfaces of the flow path block, respectively. The flow path is provided along a central axis of the flow path block to penetrate through the flow path block between the both end surfaces, and optical windows are detachably provided in outer end opening portions of extended flow paths along the central axis, to seal the outer end opening portions. Inlet and outlet paths for the fluid medium are provided along an introduction axis which intersects the central axis in the vicinity of the outer end opening portions.Type: ApplicationFiled: December 20, 2017Publication date: December 19, 2019Inventors: Haruhisa KATO, Ayako NAKAMURA
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Publication number: 20190282562Abstract: An object of the present invention is mainly to provide a medical skin external preparation that is suitable for treating superficial skin infections, in particular, superficial skin infections accompanied by blister or erosion, etc. For example, the present invention can provide a medical skin external preparation containing 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid and/or a pharmaceutically acceptable salt thereof as an active ingredient, and an alcohol and/or a fatty acid having 12 or more carbon atoms.Type: ApplicationFiled: November 30, 2017Publication date: September 19, 2019Inventors: Tomoki SAKAGUCHI, Masumi KAWAGUCHI, Ayako NAKAMURA
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Patent number: 10234370Abstract: To provide a particle size measuring device that enables simple in-line measurement of the particle size even in a case of nano-sized particles during dispersion. Provided is a particle size measuring device which measures the particle size of particles that perform Brownian motion in a dispersion medium.Type: GrantFiled: March 30, 2016Date of Patent: March 19, 2019Assignee: National Institute of Advanced Industrial Science and TechnologyInventors: Haruhisa Kato, Naoko Oouchi, Ayako Nakamura
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Patent number: 10222293Abstract: There is provided an optical characteristic measuring method for measuring an optical characteristic of an optical system which forms, on a second plane, an image of an object arranged on a first plane, the optical characteristic measuring method including: arranging, on the first plane, a first area through which a measuring light passes or by which the measuring light is reflected; arranging a second area, through which the measuring light passes or by which the measuring light is reflected, on the second plane at a position corresponding to the first area; and detecting, via one of the first area and the second area, a light amount of the measuring light via the optical system and the other of the first area and the second area; wherein at least one of the first area and the second area has a shape such that a light amount, of the measuring light which passes or which is reflected via the optical system, is changed depending on the optical characteristic.Type: GrantFiled: December 23, 2009Date of Patent: March 5, 2019Assignee: NIKON CORPORATIONInventors: Hiroshi Ooki, Ayako Nakamura
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Publication number: 20180120214Abstract: To provide a particle size measuring device that enables simple in-line measurement of the particle size even in a case of nano-sized particles during dispersion. Provided is a particle size measuring device which measures the particle size of particles that perform Brownian motion in a dispersion medium.Type: ApplicationFiled: March 30, 2016Publication date: May 3, 2018Applicant: National Institute of Advanced Industrial Science and TechnologyInventors: Haruhisa KATO, Naoko OOUCHI, Ayako NAKAMURA
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Patent number: 8901112Abstract: Provided herein are spirocyclic aminoquinolones of formula I and compositions containing the compounds. The compounds and compositions provided herein are useful in the prevention, amelioration or treatment of GSK-3 inhibitors mediated diseases.Type: GrantFiled: May 24, 2013Date of Patent: December 2, 2014Assignee: Kyorin Pharmaceutical Co., Ltd.Inventors: Oana Cociorva, Yasumichi Fukuda, Yasushi Kohno, Bei Li, Kyoko Okada, Ayako Nakamura, Masahiro Nomura, Shigeki Seto, Anna Katrin Szardenings, Kazuhiro Yumoto
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Publication number: 20140005184Abstract: Provided herein are spirocyclic aminoquinolones of formula I and compositions containing the compounds. The compounds and compositions provided herein are useful in the prevention, amelioration or treatment of GSK-3 inhibitors mediated diseases.Type: ApplicationFiled: May 24, 2013Publication date: January 2, 2014Applicant: KYORIN PHARMACEUTICALS CO., LTD.Inventors: Oana COCIORVA, Yasumichi FUKUDA, Yasushi KOHNO, Bei LI, Kyoko OKADA, Ayako NAKAMURA, Masahiro NOMURA, Shigeki SETO, Anna Katrin SZARDENINGS, Kazuhiro YUMOTO
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Patent number: 8476261Abstract: Provided herein are spirocyclic aminoquinolones of formula I and compositions containing the compounds. The compounds and compositions provided herein are useful in the prevention, amelioration or treatment of GSK-3 inhibitors mediated diseases. In Formula (I): X1 is O or NR8; A is bond or substituted or unsubstituted C1-C2 alkylene, wherein the substituents when present are selected from one to four Q2 groups; where Q2 is alkyl or haloalkyl; p is 0 or 1; and q is an integer of 0 to 2.Type: GrantFiled: September 12, 2008Date of Patent: July 2, 2013Assignee: Kyorin Pharmaceutical Co., Ltd.Inventors: Oana Cociorva, Yasumichi Fukuda, Yasushi Kohno, Bei Li, Kyoko Okada, Ayako Nakamura, Masahiro Nomura, Shigeki Seto, Anna Katrin Szardenings, Kazuhiro Yumoto