Patents by Inventor Ayrookaran J. Poulose

Ayrookaran J. Poulose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • subtilisin protease variants and compositions comprising the same
    Patent number: 11447762
    Abstract: The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: September 20, 2022
    Assignee: Danisco US Inc.
    Inventors: Viktor Yuryevich Alekseyev, Neelam S. Amin, Luis G. Cascao-Pereira, Katherine D. Collier, David A. Estell, James T. Kellis, Jr., Ayrookaran J. Poulose, Philip F. Souter, Glenn S. Ward, Katherine Augustyn, Jian Yao
  • COMPOSITIONS AND METHODS COMPRISING PROTEASE VARIANTS
    Publication number: 20220204959
    Abstract: The present invention provides protease variants, compositions comprising protease variants, and methods of using such protease variants and compositions.
    Type: Application
    Filed: December 10, 2021
    Publication date: June 30, 2022
    Inventors: AYROOKARAN J. POULOSE, JOSHUA ROY BASLER, LUIS G. CASCAO-PEREIRA, JAMES T. KELLIS, JR., ALEXANDER PISARCHIK, DANIEL ESTEBAN TORRES PAZMINO, DAVID A. ESTELL
  • Compositions containing one or more poly alpha-1,3-glucan ether compounds
    Patent number: 11015150
    Abstract: Compositions comprising cellulase and at least one poly alpha-1,3-glucan ether compound having a degree of substitution with an organic group of about 0.05-3.0 are disclosed. Such compositions can be dry or aqueous, the latter of which can have a viscosity of at least about 10 cPs. The disclosed composition can be in the form of a personal care product, household product, or industrial product, for example. Also disclosed are a method for preparing an aqueous composition comprising cellulase and a poly alpha-1,3-glucan ether compound, and a method of treating a material such as fabric by contacting it with this aqueous composition.
    Type: Grant
    Filed: January 15, 2019
    Date of Patent: May 25, 2021
    Assignee: NUTRITION & BIOSCIENCES USA 4, INC.
    Inventors: Kevin D. Nagy, Perry G. Caimi, T. Joseph Dennes, Susan Marie Hennessey, Ayrookaran J. Poulose, Jayme L. Paullin
  • FABRIC AND HOME CARE PRODUCTS
    Publication number: 20210071113
    Abstract: This invention relates to fabric and home care products comprising one or more cold water proteases and processes for making and using such products. Such compositions provide improved cleaning and freshness. Such cold water proteases may be derived from parent enzymes, including BPN? subtilisin and subtilisin derived from Bacillus lentus, by substitution, insertion and/or deletion of one or more of the parent enzymes' amino acids.
    Type: Application
    Filed: November 18, 2020
    Publication date: March 11, 2021
    Inventors: Philip Frank SOUTER, Glenn Steven WARD, Viktor Yuryevich ALEKSEYEV, Joshua Roy BASLER, Luis Gustavo CASCAO-PEREIRA, David A ESTELL, Ayrookaran J Poulose, James T KELLIS, Jr., Alexander PISARCHIK, Daniel TORRES-PAZMINO
  • Enzymatically produced cellulose
    Patent number: 10927392
    Abstract: Enzymatic reactions are disclosed herein comprising water, glucose-1-phosphate, cellodextrin, and at least one cellodextrin phosphorylase enzyme comprising an amino acid sequence that is at least 90% identical to SEQ ID NO:2 or SEQ ID NO:6. These reactions produce a low molecular weight, insoluble cellulose with enhanced features.
    Type: Grant
    Filed: August 23, 2019
    Date of Patent: February 23, 2021
    Assignee: DUPONT INDUSTRIAL BIOSCIENCES USA, LLC
    Inventors: Natnael Behabtu, Ayrookaran J. Poulose, Zheyong Yu, Zhenghong Zhang
  • Compositions and methods comprising a lipolytic enzyme variant
    Patent number: 10920204
    Abstract: The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having one or more modifications as compared to a parent lipolytic enzyme having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: February 16, 2021
    Assignee: DANISCO US INC
    Inventors: Ayrookaran J. Poulose, Thomas P. Graycar, Sina Pricelius, David A. Estell
  • Fabric and home care products comprising cold water proteases
    Patent number: 10900000
    Abstract: This invention relates to fabric and home care products comprising one or more cold water proteases and processes for making and using such products. Such compositions provide improved cleaning and freshness. Such cold water proteases may be derived from parent enzymes, including BPN? subtilisin and subtilisin derived from Bacillus lentus, by substitution, insertion and/or deletion of one or more of the parent enzymes' amino acids.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: January 26, 2021
    Assignee: The Procter & Gamble Company
    Inventors: Philip Frank Souter, Glenn Steven Ward, Viktor Yuryevich Alekseyev, Joshua Roy Basler, Luis Gustavo Cascao-Pereira, David A Estell, Ayrookaran J Poulose, James T Kellis, Jr., Alexander Pisarchik, Daniel Torres-Pazmino
  • Compositions and methods comprising a lipolytic enzyme variant
    Patent number: 10870839
    Abstract: The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having two, three, or more modifications as compared to a parent lipolytic enzyme and having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: December 22, 2020
    Assignee: DANISCO US INC
    Inventors: Thomas P. Graycar, Ayrookaran J. Poulose, David A. Estell
  • Compositions and methods comprising a lipolytic enzyme variant
    Patent number: 10865398
    Abstract: The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having one or more modifications as compared to a parent lipolytic enzyme having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.
    Type: Grant
    Filed: October 9, 2018
    Date of Patent: December 15, 2020
    Assignee: DANISCO US INC
    Inventors: Thomas P. Graycar, David A. Estell, Ayrookaran J. Poulose, Sina Pricelius
  • ENZYMATICALLY PRODUCED CELLULOSE
    Publication number: 20200080121
    Abstract: Enzymatic reactions are disclosed herein comprising water, glucose-1-phosphate, cellodextrin, and at least one cellodextrin phosphorylase enzyme comprising an amino acid sequence that is at least 90% identical to SEQ ID NO:2 or SEQ ID NO:6. These reactions produce a low molecular weight, insoluble cellulose with enhanced features.
    Type: Application
    Filed: August 23, 2019
    Publication date: March 12, 2020
    Inventors: NATNAEL BEHABTU, AYROOKARAN J. POULOSE, ZHEYONG YU, ZHENGHONG ZHANG
  • COMPOSITIONS AND METHODS COMPRISING PROTEASE VARIANTS
    Publication number: 20200080069
    Abstract: The present invention provides protease variants, compositions comprising protease variants, and methods of using such protease variants and compositions.
    Type: Application
    Filed: November 25, 2019
    Publication date: March 12, 2020
    Inventors: Ayrookaran J. Poulose, Joshua Roy Basler, Luis G. Cascao-Pereira, James T. Kellis, JR., Alexander Pisarchik, Daniel Esteban Torres Pazmino, David A. Estell
  • PROTEASE VARIANTS ACTIVE OVER A BROAD TEMPERATURE RANGE
    Publication number: 20190338267
    Abstract: The present invention provides protease compositions particularly suited for dishwashing applications.
    Type: Application
    Filed: July 23, 2019
    Publication date: November 7, 2019
    Inventors: Pieter Augustinus, Ayrookaran J. Poulose, Frits Goedegebuur, Johannes C. Van Der Laan
  • COMPOSITIONS AND METHODS COMPRISING A LIPOLYTIC ENZYME VARIANT
    Publication number: 20190233804
    Abstract: The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having two, three, or more modifications as compared to a parent lipolytic enzyme and having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.
    Type: Application
    Filed: April 11, 2019
    Publication date: August 1, 2019
    Inventors: Thomas P Graycar, Ayrookaran J. Poulose, David A. Estell
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS
    Publication number: 20190194577
    Abstract: The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: September 7, 2018
    Publication date: June 27, 2019
    Inventors: LUIS G. CASCAO-PEREIRA, DAVID A. ESTELL, FRITS GOEDEGEBUUR, JAMES T. KELLIS, JR., AYROOKARAN J. POULOSE, BRIAN F. SCHMIDT, WOLFGANG AEHLE
  • Compositions and methods comprising a lipolytic enzyme variant
    Patent number: 10329546
    Abstract: The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having two, three, or more modifications as compared to a parent lipolytic enzyme and having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: June 25, 2019
    Assignee: DANISCO US INC
    Inventors: Thomas P. Graycar, Ayrookaran J. Poulose, David A. Estell
  • COMPOSITIONS CONTAINING ONE OR MORE POLY ALPHA-1,3-GLUCAN ETHER COMPOUNDS
    Publication number: 20190144795
    Abstract: Compositions comprising cellulase and at least one poly alpha-1,3-glucan ether compound having a degree of substitution with an organic group of about 0.05-3.0 are disclosed. Such compositions can be dry or aqueous, the latter of which can have a viscosity of at least about 10 cPs. The disclosed composition can be in the form of a personal care product, household product, or industrial product, for example. Also disclosed are a method for preparing an aqueous composition comprising cellulase and a poly alpha-1,3-glucan ether compound, and a method of treating a material such as fabric by contacting it with this aqueous composition.
    Type: Application
    Filed: January 15, 2019
    Publication date: May 16, 2019
    Inventors: Kevin D. Nagy, Perry G. Caimi, T. Joseph Dennes, Susan Marie Hennessey, Ayrookaran J. Poulose, Jayme L. Paullin
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS
    Publication number: 20190136217
    Abstract: The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: July 10, 2018
    Publication date: May 9, 2019
    Inventors: Viktor Yuryevich Alekseyev, Neelam S. Amin, Luis G. Cascao-Pereira, Katherine D. Collier, David A. Estell, James T. Kellis, JR., Ayrookaran J. Poulose, Philip F. Souter, Glenn S. Ward, Katherine Augustyn, Jian Yao
  • ENZYMATICALLY PRODUCED CELLULOSE
    Publication number: 20190100782
    Abstract: Enzymatic reactions are disclosed herein comprising water, glucose-1-phosphate, cellodextrin, and at least one cellodextrin phosphorylase enzyme comprising an amino acid sequence that is at least 90% identical to SEQ ID NO:2 or SEQ ID NO:6. These reactions produce a low molecular weight, insoluble cellulose with enhanced features.
    Type: Application
    Filed: November 15, 2018
    Publication date: April 4, 2019
    Inventors: Natnael Behabtu, Ayrookaran J. Poulose, Zheyong Yu, Zhenghong Zhang
  • PROTEASE VARIANTS ACTIVE OVER A BROAD TEMPERATURE RANGE
    Publication number: 20190078070
    Abstract: The present invention provides protease compositions particularly suited for dishwashing applications.
    Type: Application
    Filed: May 15, 2018
    Publication date: March 14, 2019
    Inventors: Pieter Augustinus, Ayrookaran J. Poulose, Frits Goedegebuur, Johannes C. Van Der Laan
  • Compositions containing one or more poly alpha-1,3-glucan ether compounds
    Patent number: 10221378
    Abstract: Compositions comprising cellulase and at least one poly alpha-1,3-glucan ether compound having a degree of substitution with an organic group of about 0.05-3.0 are disclosed. Such compositions can be dry or aqueous, the latter of which can have a viscosity of at least about 10 cPs. The disclosed composition can be in the form of a personal care product, household product, or industrial product, for example. Also disclosed are a method for preparing an aqueous composition comprising cellulase and a poly alpha-1,3-glucan ether compound, and a method of treating a material such as fabric by contacting it with this aqueous composition.
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: March 5, 2019
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Kevin D Nagy, Perry G Caimi, T Joseph Dennes, Susan Marie Hennessey, Ayrookaran J. Poulose, Jayme L Paullin