Patents by Inventor Azizah M. Malebari

Azizah M. Malebari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FLAVONOIDS AND LINOLEIC ACID USES IN HYPERTENSION
    Publication number: 20220280425
    Abstract: Methoxylated flavonoids are described for their compositions and uses in hypertension treatment as vasodilators. The flavonoids are intravenously administered in a self-nanoemulsifying drug delivery system (SNEDDS) in combination with linoleic acid which provides lowering heart rate, thus suppressing reflex tachycardia elicited by the vasodilating effect of flavonoids. The compositions are used to treat or prevent acute hypertension or any acute symptoms of emergency hypertension.
    Type: Application
    Filed: March 3, 2021
    Publication date: September 8, 2022
    Inventors: Hossam M. Abdallah, Hany Mohamed El-Bassossy, Ali M. El-Halawany, Tarek A. Ahmed, Gamal A. Mohamed, Azizah M. Malebari, Noura Ahmed Hassan
  • 3-vinylquinolines as cancer cells inhibitors
    Patent number: 11345692
    Abstract: 3-vinylquinolines analogs and methods of synthesizing the derivatives/analogs are provided. In particular, the compounds are useful for the treatment of cancer.
    Type: Grant
    Filed: November 16, 2020
    Date of Patent: May 31, 2022
    Assignee: King Abdulaziz University
    Inventors: Tarek Salah Ibrahim, Mohamed Moustafa Hawwas, Azizah M. Malebari, Moustafa E. El-Araby, Abdelsattar M. Omar
  • Method for treating stomach cancer
    Patent number: 11325885
    Abstract: Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Grant
    Filed: August 19, 2021
    Date of Patent: May 10, 2022
    Assignee: King Abdulaziz University
    Inventors: Moustafa E. El-Araby, Abdelsattar M. Omar, Maan T. Khayat, Dhaval Shah, Martin K. Safo, Azizah M. Malebari, Farid Ahmed
  • Method for treating a patient having a colon cancer
    Patent number: 11312680
    Abstract: Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Grant
    Filed: August 19, 2021
    Date of Patent: April 26, 2022
    Assignee: King Abdulaziz University
    Inventors: Moustafa E. El-Araby, Abdelsattar M. Omar, Maan T. Khayat, Dhaval Shah, Martin K. Safo, Azizah M. Malebari, Farid Ahmed
  • Chemotherapeutic oxazolone derivatives and pharmaceutical compositions thereof
    Patent number: 11220485
    Abstract: Cytotoxic compounds containing a phenyl core, amide link(s), an imidazolinone or a propenamide moiety. Also described are pharmaceutical compositions incorporating the cytotoxic compounds and methods for treating cancer. These compounds are cytotoxic against breast, prostate, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Grant
    Filed: July 16, 2021
    Date of Patent: January 11, 2022
    Assignee: King Abdulaziz University
    Inventors: Moustafa E. El-Araby, Abdelsattar M. Omar, Ahmed Esmat, Farid Ahmed, Azizah M. Malebari, Ashraf B. Abdel-Naim, Thikryat Neamatallah
  • Method for making anti-cancer compounds
    Patent number: 11214537
    Abstract: Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Grant
    Filed: July 16, 2021
    Date of Patent: January 4, 2022
    Assignee: King Abdulaziz University
    Inventors: Moustafa E. El-Araby, Abdelsattar M. Omar, Maan T. Khayat, Dhaval Shah, Martin K. Safo, Azizah M. Malebari, Farid Ahmed
  • METHOD FOR TREATING A PATIENT HAVING A COLON CANCER
    Publication number: 20210395187
    Abstract: Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Application
    Filed: August 19, 2021
    Publication date: December 23, 2021
    Applicant: King Abdulaziz University
    Inventors: Moustafa E. EL-ARABY, Abdelsattar M. OMAR, Maan T. KHAYAT, Dhaval SHAH, Martin K. SAFO, Azizah M. MALEBARI, Farid AHMED
  • METHOD FOR TREATING STOMACH CANCER
    Publication number: 20210380526
    Abstract: Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Application
    Filed: August 19, 2021
    Publication date: December 9, 2021
    Applicant: King Abdulaziz University
    Inventors: Moustafa E. EL-ARABY, Abdelsattar M. OMAR, Maan T. KHAYAT, Dhaval SHAH, Martin K. SAFO, Azizah M. MALEBARI, Farid AHMED
  • Anticancer compounds, pharmaceutical compositions thereof, and a method of treating cancer
    Patent number: 11180458
    Abstract: Cytotoxic compounds containing a phenyl core, amide link(s), an imidazolinone or a propenamide moiety. Also described are pharmaceutical compositions incorporating the cytotoxic compounds and methods for treating cancer. These compounds are cytotoxic against breast, prostate, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: November 23, 2021
    Assignee: King Abdulaziz University
    Inventors: Moustafa E. El-Araby, Abdelsattar M. Omar, Ahmed Esmat, Farid Ahmed, Azizah M. Malebari, Ashraf B. Abdel-Naim, Thikryat Neamatallah
  • Anti-cancer compounds having oxazolone derivation
    Patent number: 11174233
    Abstract: Cytotoxic compounds containing a phenyl core, amide link(s), an imidazolinone or a propenamide moiety. Also described are pharmaceutical compositions incorporating the cytotoxic compounds and methods for treating cancer. These compounds are cytotoxic against breast, prostate, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Grant
    Filed: July 16, 2021
    Date of Patent: November 16, 2021
    Assignee: King Abdulaziz University
    Inventors: Moustafa E. El-Araby, Abdelsattar M. Omar, Ahmed Esmat, Farid Ahmed, Azizah M. Malebari, Ashraf B. Abdel-Naim, Thikryat Neamatallah
  • METHOD FOR MAKING ANTI-CANCER COMPOUNDS
    Publication number: 20210340097
    Abstract: Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Application
    Filed: July 16, 2021
    Publication date: November 4, 2021
    Applicant: King Abdulaziz University
    Inventors: Moustafa E. EL-ARABY, Abdelsattar M. OMAR, Maan T. KHAYAT, Dhaval SHAH, Martin K. SAFO, Azizah M. MALEBARI, Farid AHMED
  • CHEMOTHERAPEUTIC OXAZOLONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF
    Publication number: 20210340110
    Abstract: Cytotoxic compounds containing a phenyl core, amide link(s), an imidazolinone or a propenamide moiety. Also described are pharmaceutical compositions incorporating the cytotoxic compounds and methods for treating cancer. These compounds are cytotoxic against breast, prostate, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Application
    Filed: July 16, 2021
    Publication date: November 4, 2021
    Applicant: King Abdulaziz University
    Inventors: Moustafa E. EL-ARABY, Abdelsattar M. Omar, Ahmed Esmat, Farid Ahmed, Azizah M. Malebari, Ashraf B. Abdel-Naim, Thikryat Neamatallah
  • Pharmaceutical composition for treating cancer
    Patent number: 11142493
    Abstract: Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Grant
    Filed: June 23, 2021
    Date of Patent: October 12, 2021
    Assignee: King Abdulaziz University
    Inventors: Moustafa E. El-Araby, Abdelsattar M. Omar, Maan T. Khayat, Dhaval Shah, Martin K. Safo, Azizah M. Malebari, Farid Ahmed
  • Method for treating a patient having cancer
    Patent number: 11136288
    Abstract: Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Grant
    Filed: March 4, 2021
    Date of Patent: October 5, 2021
    Assignee: King Abdulaziz University
    Inventors: Moustafa E. El-Araby, Abdelsattar M. Omar, Maan T. Khayat, Dhaval Shah, Martin K. Safo, Azizah M. Malebari, Farid Ahmed
  • METHOD FOR TREATING A PATIENT HAVING CANCER
    Publication number: 20210188765
    Abstract: Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Application
    Filed: March 4, 2021
    Publication date: June 24, 2021
    Applicant: King Abdulaziz University
    Inventors: Moustafa E. EL-ARABY, Abdelsattar M. Omar, Maan T. Khayat, Dhaval Shah, Martin K. Safo, Azizah M. Malebari, Farid Ahmed
  • ANTICANCER COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND A METHOD OF TREATING CANCER
    Publication number: 20210139434
    Abstract: Cytotoxic compounds containing a phenyl core, amide link(s), an imidazolinone or a propenamide moiety. Also described are pharmaceutical compositions incorporating the cytotoxic compounds and methods for treating cancer. These compounds are cytotoxic against breast, prostate, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Application
    Filed: November 12, 2019
    Publication date: May 13, 2021
    Applicant: King Abdulaziz University
    Inventors: Moustafa E. EL-ARABY, Abdelsattar M. OMAR, Ahmed ESMAT, Farid AHMED, Azizah M. MALEBARI, Ashraf B. ABDEL-NAIM, Thikryat NEAMATALLAH
  • Cytotoxic compounds, pharmaceutical compositions thereof, and methods of treating cancer
    Patent number: 10988439
    Abstract: Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: April 27, 2021
    Assignee: King Abdulaziz University
    Inventors: Moustafa E. El-Araby, Abdelsattar M. Omar, Maan T. Khayat, Dhaval Shah, Martin K. Safo, Azizah M. Malebari, Farid Ahmed
  • 3-vinylquinolines as cancer cells inhibitors
    Patent number: 10882852
    Abstract: 3-vinylquinolines analogs and methods of synthesizing the derivatives/analogs are provided. In particular, the compounds are useful for the treatment of cancer.
    Type: Grant
    Filed: July 9, 2020
    Date of Patent: January 5, 2021
    Assignee: King Abdulaziz University
    Inventors: Tarek Salah Ibrahim, Mohamed Moustafa Hawwas, Azizah M. Malebari, Moustafa E. El-Araby, Abdelsattar M. Omar
  • AMIDE GROUP-CONTAINING COMPOUNDS AND USE FOR CANCER TREATMENT
    Publication number: 20200385337
    Abstract: Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Application
    Filed: August 6, 2020
    Publication date: December 10, 2020
    Applicant: King Abdulaziz University
    Inventors: Moustafa E. El-Araby, Abdelsattar M. Omar, Maan T. Khayat, Dhaval Shah, Martin K. Safo, Azizah M. Malebari, Farid Ahmed
  • CYTOTOXIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF TREATING CANCER
    Publication number: 20200385336
    Abstract: Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
    Type: Application
    Filed: June 4, 2019
    Publication date: December 10, 2020
    Applicant: King Abdulaziz University
    Inventors: Moustafa E. El-Araby, Abdelsattar M. Omar, Maan T. Khayat, Dhaval Shah, Martin K. Safo, Azizah M. Malebari, Farid Ahmed