Patents by Inventor Azok Nath

Azok Nath has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of N,N-dimethyl-3-(4-methyl) benzoyl propionamide a key intermediate of zolpidem
    Patent number: 6921839
    Abstract: The present invention relates to an improved and industrially advantageous process for the preparation of N,N-dimethyl-3-(4-methyl)benzoyl propionamide of Formula I, which is a key intermediate in the synthesis of zolpidem hemitartrate, a non-benzodiazepine hypnotic agent. The process includes reacting 3-(4-methyl)-benzoyl propionic acid of Formula IV, with alkyl chloroformate or pivaloyl chloride to get a mixed anhydride of Formula V; and reacting the mixed anhydride of Formula V with dimethylamine of Formula VI to get the N,N-dimethyl-3-(4-methyl)benzoyl propionamide of Formula I.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: July 26, 2005
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Yatendra Kumar, Mohan Prasad, Azok Nath
  • Synthesis of n,n-dimethyl-3-(4-methyl) benzoyl propionamide a key intermediate of zolpidem
    Publication number: 20040054230
    Abstract: The present invention relates to an improved and industrially advantageous process for the preparation of N, N-dimethyl-3-(4-methyl)benzoyl propionamide, which compound is a key intermediate for the synthesis of zolpidem hemitartrate, a non-benzodiazepine hypnotic agent.
    Type: Application
    Filed: September 17, 2003
    Publication date: March 18, 2004
    Inventors: Yatendra Kumar, Mohan Prasad, Azok Nath