Abstract: Provided herein is a method of promoting tissue repair, comprising delivering to a subject a therapeutically effective amount of fibromodulin (FMOD), FMOD polypeptide, FMOD peptide, or a variant or derivative or analog thereof according to a dosing regimen to cause an injured tissue to form a repaired tissue having an improved condition provided that the improved condition does not include improved condition of scar of skin.

Abstract: The present invention discloses methods and compositions for treating or ameliorating a condition associated with increased or decreased myofibroblast activities and use thereof.

Abstract: Embodiments of the present invention provide an osteogenic composition comprising perivascular stem cells or induced pluripotent cells (iPS) and an osteogenic agent and methods of making and using the same.

Abstract: Provided herein is a biocompatible device comprising a body structure and a wound-healing-enhancing agent in a wound-healing-enhancing effective amount, wherein the wound-healing-enhancing agent is embedded within the body structure or coated on the body structure. An example of the device is a surgical suture. Methods of fabricating and using the device are also provided.

Abstract: The present invention provides a method of forming a fibromodulin (FMOD) reprogrammed (FReP) cell. This application includes the sequence listing which is identical to the sequence information in the last filed computer readable form (CFR) on Aug. 1, 2014 in U.S. application Ser. No. 14/353,284, filed Apr. 21, 2014, entitled “2014-08-01 384578-991391 ST25.tax” and is hereby incorporated by reference in its entirety.

Abstract: The present invention provides a method of treating a disorder using a fibromodulin (FMOD) reprogrammed (FReP) cell.

Abstract: The present invention provides a fibromodulin (FMOD) reprogrammed (FReP) cell and a method of making therefor, a culture medium therefor, and a supernatant thereof, and methods of making and using these.

Abstract: Disclosed herein is a method of making a fibromodulin peptide (FMOD-P), compositions thereof, and methods of using the FMOD-P and the compositions thereof for treating or ameliorating a condition.

Abstract: Embodiments of the present invention provide a population of purified perivascular stem cells (PSC) or induced pluripotent stem cells (iPS) and a supernatant of stem cell free from the stem cell, a composition comprising any of these, and a method of using and making them.

Abstract: Embodiments of the present invention provide a fibromodulin (FMOD) peptide (FMOD-P), a composition and a formulation comprising a FMOD-P, option-ally with a TGF-? isoform, or comprising FMOD with a TGF-? isoform. The present invention also provides methods of making and using the FMOD-P, composition, or formulation.

Abstract: Embodiments of the present invention provide a population of purified perivascular stem cells (PSC) or induced pluripotent stem cells (iPS) and a supernatant of stem cell free from the stem cell, a composition comprising any of these, and a method of using and making them.

Abstract: A transcutaneous multimodal delivery device for drug delivery and the methods of making and using the same are provided.

Abstract: The present invention provides a fibromodulin (FMOD) reprogrammed (FReP) cell and a method of making therefor, a culture medium therefor, and a supernatant thereof, and methods of making and using these.

Abstract: Implant-associated bacterial infections are one of the most serious complications in orthopedic surgery. Treatment of these infections often requires multiple operations, device removal, long-term systemic antibiotics, and extended rehabilitation, and is frequently ineffective, leading to worse clinical outcomes and increased financial costs. Silver nanoparticle/poly(DL-lactic-co-glycolic acid) (PLGA)-coated stainless steel alloy (SNPSA) was evaluated as a potential antimicrobial implant material. It was found that SNPSA exhibited strong antibacterial activity in vitro and ex vivo, and promoted MC3T3-E1 pre-osteoblasts proliferation and maturation in vitro. Furthermore, SNPSA implants induced osteogenesis while suppressing bacterial survival in contaminated rat femoral canals. The results indicate that SNPSA has simultaneous antimicrobial and osteoinductive properties that make it a promising therapeutic material in orthopedic surgery.

Abstract: The present invention discloses methods and compositions for treating or ameliorating a condition associated with increased or decreased myofibroblast activities and use thereof

Abstract: Provided herein is a cyclic interruptive force orthodontic device and a system comprising the same. Methods of making and using the same are also provided.

Abstract: Embodiments of the present invention provide a population of purified perivascular stem cells (PSC) or induced pluripotent stem cells (iPS) and a supernatant of stem cell free from the stem cell, a composition comprising any of these, and a method of using and making them.

Abstract: Provided herein is a force system for repositioning teeth and the methods of making and using the system.

Abstract: Embodiments of the present invention provide an osteogenic composition comprising perivascular stem cells or induced pluripotent cells (iPS) and an osteogenic agent and methods of making and using the same.

Abstract: Embodiments of the present invention provide a composition comprising perivascular stem cells or induced pluripotent cells (iPS) and a NELL-1 factor for cardiac or vascular regeneration and methods of making and using the same.