Patents by Inventor Babu Joseph

Babu Joseph has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spiro-oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators
    Patent number: 7485722
    Abstract: Compounds in accord with Formula I: wherein R1, L, A, B, D, E, m, n, x and y are as defined in the description, processes for the preparation of such compounds and to new intermediates employed in the preparation thereof, pharmaceutical compositions containing such compounds, and the use of such compounds in therapy and for the treatment of diseases mentioned in the specification.
    Type: Grant
    Filed: September 12, 2007
    Date of Patent: February 3, 2009
    Assignee: AstraZeneca AB
    Inventors: Ian Egle, Babu Joseph, Abdelmalik Slassi, Methvin Isaac, Fupeng Ma, Joshua Clayton
  • Oxazolidinone Compounds and Their Use as Metabotropic Glutamate Receptor Potentiators
    Publication number: 20090012089
    Abstract: The present invention is directed to compounds of Formula I: Wherein R1, R2, Y, m and n are further defined in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
    Type: Application
    Filed: December 6, 2006
    Publication date: January 8, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Abdelmalik Slassi, Babu Joseph, Fupeng Ma, Ian Egle, Joshua Clayton, Methvin Isaac, Krzysztof Swierczek
  • Spiro-oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators
    Publication number: 20080125431
    Abstract: Compounds in accord with Formula I: wherein R1, L, A, B, D, E, m, n, x and y are as defined in the description, processes for the preparation of such compounds and to new intermediates employed in the preparation thereof, pharmaceutical compositions containing such compounds, and the use of such compounds in therapy and for the treatment of diseases mentioned in the specification.
    Type: Application
    Filed: September 12, 2007
    Publication date: May 29, 2008
    Applicant: ASTRAZENECA
    Inventors: Ian Egle, Babu Joseph, Abdelmalik Slassi, Methvin Isaac, Fupeng Ma, Joshua Clayton
  • Oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators
    Publication number: 20070275966
    Abstract: The present invention is directed to compounds of Formula I: Wherein R1, R2, Y, m and n are further defined in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
    Type: Application
    Filed: December 6, 2006
    Publication date: November 29, 2007
    Applicants: NPS PHARMACEUTICALS, INC., AstraZeneca AB
    Inventors: Abdelmalik Slassi, Methvin Isaac, Ian Egle, Fupeng Ma, Babu Joseph, Joshua Clayton, Krzysztof Swierczek
  • Pseudo- and non-peptide bradykinin receptor antagonists
    Patent number: 5817756
    Abstract: The invention provides bradykinin antagonist compounds wherein many (or all) of the peptide bonds of bradykinin are eliminated to yield compounds which specifically compete with bradykinin for binding to the bradykinin receptor. More particularly, the invention relates to compounds having, in appropriate spatial arrangement, two positively charged moieties flanking a hydrophobic organic moiety and a moiety which mimics a beta turn conformation.
    Type: Grant
    Filed: March 9, 1995
    Date of Patent: October 6, 1998
    Assignee: Scios Inc.
    Inventors: Donald James Kyle, Babu Joseph Mavunkel, Sarjavit Chakravarty, Zhijian Lu
  • Bradykinin antagonist pseudopeptide derivatives of aminoalkanoic acids and related olefins
    Patent number: 5686565
    Abstract: Pseudopeptide compounds based on a modified bradykinin sequence are potent bradykinin receptor antagonist. All or a portion of the amino acids at positions 2 through 5 of the bradykinin sequence are replaced by 2-pyrrolidinyl and/or amino-alkanoic acid or related olefinic derivatives to reduce the peptidic nature of the compounds.The analogs produced are useful in treating conditions and diseases of a mammal and human in which an excess of bradykinin or related kinins are produced or injected such as by insect bites.
    Type: Grant
    Filed: July 28, 1994
    Date of Patent: November 11, 1997
    Assignee: Scios Inc.
    Inventors: Donald James Kyle, Babu Joseph Mavunkel