Patents by Inventor Balanarasimha Reddy Gona

Balanarasimha Reddy Gona has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of Dutasteride
    Patent number: 8563728
    Abstract: The present invention provides an improved process for the preparation of Dutasteride (I) which comprises: (i) reacting 4-aza-5?-androst-1-en-3-one-17?-carboxylic acid (VII), Formula VII with sulfonic acid anhydride (RSO2)2O in presence of base to produce an intermediate compound of Formula (XIII), wherein R represents C1-6 alkyl, C1-6 halo alkyl, C6-10 aryl, halo aryl; (ii) condensing compound of Formula (XIII) with 2,5-bis(trifluoromethyl)aniline (III), Formula (III) in the presence or absence of a base to produce Dutasteride (I).
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: October 22, 2013
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Balanarasimha Reddy Gona, Naresh Akkina, Rani Ananta, Islam Aminul, Sivakumaran Meenakshisunderam
  • PROCESS FOR THE PREPARATION OF DUTASTERIDE
    Publication number: 20120157683
    Abstract: The present invention provides an improved process for the preparation of Dutasteride (I) which comprises: (i) reacting 4-aza-5?-androst-1-en-3-one-17?-carboxylic acid (VII), Formula VII with sulfonic acid anhydride (RSO2)2O in presence of base to produce an intermediate compound of Formula (XIII), wherein R represents C1-6 alkyl, C1-6 halo alkyl, C6-10 aryl, halo aryl; (ii) condensing compound of Formula (XIII) with 2,5-bis(trifluoromethyl)aniline (III), Formula (III) in the presence or absence of a base to produce Dutasteride (I).
    Type: Application
    Filed: July 7, 2010
    Publication date: June 21, 2012
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Balanarasimha Reddy Gona, Naresh Akkina, Rami Ananta, Islam Aminul, Sivakumaran Meenakshisunderam