Abstract: Testing devices are provided for detecting the level of one or more analytes in a fluid. In an example, a testing device includes a fluid collection device adapted to collect a fluid, and an assembly including a filter coupled to a test matrix, the test matrix including one or more lateral flow strips adapted to optically indicate a level of one or more analytes in the fluid, where the fluid collection device is configured to supply the fluid to the one or more lateral flow strips via the filter.

Abstract: Methods, systems, kits, and other techniques and discoveries for the prediction, detection, monitoring, treatment, and general diagnosis and prognosis of Alzheimer's disease (AD) in subjects utilizing information obtained by detection of biomarkers and biomarker combinations present in the saliva of subjects afflicted with AD. Aspects of the invention may be implemented to detect, monitor, treat and diagnose subjects who are asymptomatic of AD early in the disease process. Other aspects of the invention may be implemented to identify and differentiate the level of severity of AD in a subject such as, for example, identification of mild AD in a subject who is completely asymptomatic of AD, differentiation of mild AD from moderate AD, and differentiation of moderate AD from severe AD.

Abstract: Methods and systems for the diagnosis, treatment, and management of gastroesophageal diseases including gastroesophageal reflux disease, reflux laryngitis, nonerosive reflux disease and gastric cancer using saliva based biomarkers are presented herein.

Abstract: Methods and systems for diagnosis, detection, monitoring, and treatment of traumatic brain injury are described. The methods and systems include detection of salivary biomarkers associated with brain injury in a human subject, one application of which is to determine whether the subject has sustained a concussion or a more severe traumatic brain injury (TBI). Detection of the salivary biomarkers can also provide a basis to determine that a subject can safely return to play in an athletic event and can provide a basis to evaluate the efficacy of particular treatments. The methods and systems may be implemented, for example, by means of a kit.

Abstract: Methods, systems, and kits for detection, diagnosis, monitoring, and/or treatment of viral infections such as represented by the COVID-19 disease are described. The methods, systems, and kits are capable of detection of salivary biomarkers which correlate with, and are indicative of, COVID-19 in a subject. Detection of the biomarkers in a saliva sample provides opportunities for a COVID-19 or other viral detection assay which is non-invasive, produces rapid results, and can be implemented in the field on a wide geographic basis for individualized screening or mass screenings for COVID-19 or other viral infections.

Abstract: Assay devices, systems, methods, and kits useful for detection of analytes in a bodily fluid sample, such as saliva, are disclosed herein. Assay devices may include a fluid sample collector and an assessment unit to which the fluid sample collector couples. The fluid sample collector may include a cap with a plunger and absorbent member that collects a bodily fluid sample. Insertion of the plunger into the assessment unit during coupling provides pressure-driven fluid flow through a filter rapidly delivering bodily fluid filtrate to one or more test panels which provide the assay result. In embodiments, an on-board light source enables a user to readily detect changes in a test panel indicative of the presence of an analyte thus providing an opportunity for obtaining rapid results with improved confidence.

Abstract: A method for the risk detection, early diagnosis, prognosis, and monitoring of Alzheimer's disease in an individual by measuring the amount of specific biomarkers present in a bodily fluid and comparing them to a reference level of biomarkers in a sample from a healthy person, a person previously diagnosed with Alzheimer's disease, or an earlier sample from the individual of interest.

Abstract: A method for the risk detection, early diagnosis, prognosis, and monitoring of Parkinson's disease in an individual by measuring the amount of specific biomarkers present in a bodily fluid and comparing them to a reference level of biomarkers in a sample from a healthy person, a person previously diagnosed with Parkinson's disease, or an earlier sample from the individual of interest.

Abstract: Methods and compositions for risk detection, early diagnosis, prognosis, and monitoring of sleepiness in an individual by measuring the amount of specific biomarkers present in a bodily fluid and comparing them to a reference level of biomarkers in a sample from a healthy person, a person previously diagnosed with sleepiness, or an earlier sample from the individual of interest.

Abstract: A method for the risk detection, early diagnosis, prognosis, and monitoring of Alzheimer's disease in an individual by measuring the amount of specific biomarkers present in a bodily fluid and comparing them to a reference level of biomarkers in a sample from a healthy person, a person previously diagnosed with Alzheimer's disease, or an earlier sample from the individual of interest.

Abstract: A method for the risk detection, early diagnosis, prognosis, and monitoring of Alzheimer's disease in an individual by measuring the amount of specific biomarkers present in a bodily fluid and comparing them to a reference level of biomarkers in a sample from a healthy person, a person previously diagnosed with Alzheimer's disease, or an earlier sample from the individual of interest.

Abstract: A storage system graphical user interface (GUI) renders indication of a plurality of selected storage systems. Selection is received of selected storage systems from the rendered indication of selected storage systems and a determination is made of performance metrics common to the selected storage systems. A performance metric GUI enabling selection of the determined performance metrics common to the selected storage systems is generated. In response to user selection of at least one selected performance metric of the determined performance metrics in the performance metric GUI, determination is made of performance metric values for the at least one of the selected performance metrics for the selected storage systems. A computer renderable visualization providing a visual comparison for each of the at least one selected performance metric of the determined performance metric values is generated for the selected storage systems.

Abstract: A method for the risk detection, early diagnosis, prognosis, and monitoring of Alzheimer's disease in an individual by measuring the amount of specific biomarkers present in a bodily fluid and comparing them to a reference level of biomarkers in a sample from a healthy person, a person previously diagnosed with Alzheimer's disease, or an earlier sample from the individual of interest.

Abstract: A method for the risk detection, early diagnosis, prognosis, and monitoring of Parkinson's disease in an individual by measuring the amount of specific biomarkers present in a bodily fluid and comparing them to a reference level of biomarkers in a sample from a healthy person, a person previously diagnosed with Parkinson's disease, or an earlier sample from the individual of interest.

Abstract: Methods by which specific biomarkers in saliva are used for risk detection, early diagnosis, prognosis and monitoring of Alzheimer's and Parkinson's diseases.

Abstract: Methods by which specific biomarkers in saliva are used for risk detection, early diagnosis, prognosis and monitoring of Alzheimer's and Parkinson's diseases.