Abstract: Examples described herein relate to accessing an initiator as a Non-Volatile Memory Express (NMVe) device. In some examples, the initiator is configured with an address space, configured in kernel or user space, for access by a virtualized execution environment. In some examples, the initiator to copy one or more storage access commands from the virtualized execution environment into a queue for access by a remote direct memory access (RDMA) compatible network interface. In some examples, the network interface to provide Non-Volatile Memory Express over Fabrics (NVMe-oF) compatible commands based on the one or more storage access commands to a target storage device. In some examples, the initiator is created as a mediated device in kernel space or user space of a host system. In some examples, configuration of a physical storage pool address of the target storage device for access by the virtualized execution environment occurs by receipt of the physical storage pool address in a configuration command.