Patents by Inventor Barbara A. Soltz
Barbara A. Soltz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20160250377Abstract: A light activated collagen-flavin composite layer incorporating riboflavin is applied as treatment for infected lesions. These composites have also been found to be strong tissue adhesives that are effective in closing and sealing wounds, fixation of grafts/ implants and anastomoses. Advantages include speed of closure, reduced infection due to the elimination of foreign matter, evidence of accelerated wound healing and the ease of use in complex surgery, especially when watertight seals, limited access or small repair size are important factors. The riboflavin in the collagen layer is exposed to light (e.g., light having a wavelength between 360-375 nm or 440-480 nm), decomposing the riboflavin to form reactive oxygen species (ROS). Strong crosslinks between the collagen composite and tissue results. In addition, similar exposures eradicate pathogens in the wound.Type: ApplicationFiled: March 13, 2015Publication date: September 1, 2016Applicant: CONVERSION ENERGY ENTERPRISES, INC.Inventors: Barbara A. Soltz, Robert Soltz
-
Patent number: 9012406Abstract: Disclosed herein are compositions comprising gelatin, collagen, and a chromophore that produces a reactive oxygen species upon exposure to electromagnetic radiation. These compositions have also been found to be strong tissue adhesives that crosslinks the composition and tissue and are effective in closing and sealing wounds, fixation of grafts/implants and anastomoses.Type: GrantFiled: November 10, 2010Date of Patent: April 21, 2015Assignee: Conversion Energy Enterprises, Inc.Inventors: Barbara A. Soltz, Robert Soltz
-
Patent number: 9006182Abstract: A light activated collagen-flavin composite layer incorporating riboflavin is applied as treatment for infected lesions. These composites have also been found to be strong tissue adheives that are effective in closing and sealing wounds, fixation of grafts/ implants and anastomoses. Advantages include speed of closure, reduced infection due to the elimination of foreign matter, evidence of accelerated wound healing and the ease of use in complex surgery, especially when watertight seals, limited access or small repair size are important factors. The riboflavin in the collagen layer is exposed to light (e.g., light having a wavelength between 360-375 nm or 440-480 nm), decomposing the riboflavin to form reactive oxygen species (ROS). Strong crosslinks between the collagen composite and tissue results. In addition, similar exposures eradicate pathogens in the wound.Type: GrantFiled: November 10, 2010Date of Patent: April 14, 2015Assignee: Conversion Energy Enterprises, Inc.Inventors: Barbara A. Soltz, Robert Soltz
-
Publication number: 20130190245Abstract: A light activated collagen-flavin composite layer incorporating riboflavin is applied as treatment for infected lesions caused by bacteria and as the consequence of surgical procedures. These composites have also been found to be strong tissue adhesives that are effective in closing and sealing wounds, fixation of grafts/ implants and anastomoses. Advantages include speed of closure, reduced infection due to the elimination of foreign matter, evidence of accelerated wound healing and the ease of use in complex surgery, especially when watertight seals, limited access or small repair size are important factors. The riboflavin in the collagen layer is exposed to light (e.g., light having a wavelength between 360-375 nm or 440-480 nm), decomposing the riboflavin to form reactive oxygen species (ROS). Strong crosslinks between the collagen composite and tissue results. In addition, similar exposures eradicate pathogens in the wound is eradicated resulting in a sterile wound.Type: ApplicationFiled: November 10, 2010Publication date: July 25, 2013Inventors: Barbara A. Soltz, Robert Soltz
-
Publication number: 20130035629Abstract: A pad is provided that supplies light to a composite layer, which may be provided on a wound. The composite layer may include a combination including a form of collagen and a chromophore that releases a reactive oxygen species upon exposure to the light. The reactive oxygen species may then act to kill bacteria or other microorganisms in the wound.Type: ApplicationFiled: August 6, 2012Publication date: February 7, 2013Inventors: Barbara A. Soltz, Robert Soltz
-
Publication number: 20110125187Abstract: A light activated collagen-flavin composite layer incorporating riboflavin is applied as treatment for infected lesions caused by bacteria and as the consequence of surgical procedures. These composites have also been found to be strong tissue adhesives that are effective in closing and sealing wounds, fixation of grafts/implants and anastomoses. Advantages include speed of closure, reduced infection due to the elimination of foreign matter, evidence of accelerated wound healing and the ease of use in complex surgery, especially when watertight seals, limited access or small repair size are important factors. The riboflavin in the collagen layer is exposed to light (e.g., light having a wavelength between 360-375 nm or 440-480 nm), decomposing the riboflavin to form reactive oxygen species (ROS). Strong crosslinks between the collagen composite and tissue results. In addition, similar exposures eradicate pathogens in the wound is eradicated resulting in a sterile wound.Type: ApplicationFiled: November 10, 2010Publication date: May 26, 2011Inventors: Barbara A. Soltz, Robert Soltz
-
Patent number: 6939364Abstract: Consistent with the present invention, tissue adhesive compositions and an associated laser exposure system are provided for bonding or sealing biological tissues. The compositions are comprised of chemically derivatized soluble collagen which is formulated to concentrations ranging from 300 mg/ml (30%) to 800 mg/ml (80%) collagen protein. In particular, Type I collagen, for example, is first prepared by extraction from bovine or porcine hide and purified. The collagen preparations are then chemically derivatized with sulfhydryl reagents to improve cohesive strength and with secondary derivatizing agents, such as carboxyl groups, to improve the adhesive strength of the solder to the tissue. The compositions are then formed into viscous solutions, gels or solid films, which when exposed to energy generated from an infrared laser, for example, undergo thermally induced phase transitions.Type: GrantFiled: October 9, 2001Date of Patent: September 6, 2005Assignee: Tissue Adhesive Technologies, Inc.Inventors: Barbara A. Soltz, Dale P. DeVore, Braden P. DeVore, Robert Soltz, Michael A. Soltz
-
Patent number: 6875427Abstract: Consistent with the present invention, tissue adhesive compositions and an associated laser exposure system are provided for bonding or sealing biological tissues. The compositions are comprised of chemically derivatized soluble collagen which is formulated to concentrations ranging from 300 mg/ml (30%) to 800 mg/ml (80%) collagen protein. In particular, Type I collagen, for example, is first prepared by extraction from bovine or porcine hide and purified. The collagen preparations are then chemically derivatized with sulfhydryl reagents to improve cohesive strength and with secondary derivatizing agents, such as carboxyl groups, to improve the adhesive strength of the solder to the tissue. The compositions are then formed into viscous solutions, gels or solid films, which when exposed to energy generated from an infrared laser, for example, undergo thermally induced phase transitions.Type: GrantFiled: October 9, 2001Date of Patent: April 5, 2005Assignee: Tissue Adhesive Technologies, Inc.Inventors: Dale P. DeVore, Braden P. DeVore, Barbara A. Soltz, Robert Soltz, Michael A. Soltz
-
Patent number: 6780840Abstract: Consistent with the present invention, tissue adhesive compositions and an associated laser exposure system are provided for bonding or sealing biological tissues. The compositions are comprised of chemically derivatized soluble collagen which is formulated to concentrations ranging from 300 mg/ml (30%) to 800 mg/ml (80%) collagen protein. In particular, Type I collagen, for example, is first prepared by extraction from bovine or porcine hide and purified. The collagen preparations are then chemically derivatized with sulfhydryl reagents to improve cohesive strength and with secondary derivatizing agents, such as carboxyl groups, to improve the adhesive strength of the solder to the tissue. The compositions are then formed into viscous solutions, gels or solid films, which when exposed to energy generated from an infrared laser, for example, undergo thermally induced phase transitions.Type: GrantFiled: October 9, 2001Date of Patent: August 24, 2004Assignee: Tissue Adhesive Technologies, Inc.Inventors: Dale P. DeVore, Braden P. DeVore, Barbara A. Soltz, Robert Soltz, Michael A. Soltz
-
Patent number: 6773699Abstract: Consistent with the present invention, tissue adhesive compositions and an associated laser exposure system are provided for bonding or sealing biological tissues. The compositions are comprised of chemically derivatized soluble collagen which is formulated to concentrations ranging from 300 mg/ml (30%) to 80 mg/ml (80%) collagen protein. In particular, Type I collagen, for example, is first prepared by extraction from bovine or porcine hide and purified. The collagen preparations are then chemically derivatized with sulfhydryl reagents to improve cohesive strength and with secondary derivatizing agents, such as carboxyl groups, to improve the adhesive strength of the solder to the tissue. The compositions are then formed into viscous solutions, gels or solid films which are used to encapsulate structural components such as a cojoinal network or mesh. The resultant patch which when exposed to energy generated from an infrared laser, for example, undergo thermally induced phase transitions.Type: GrantFiled: October 9, 2001Date of Patent: August 10, 2004Assignee: Tissue Adhesive Technologies, Inc.Inventors: Barbara A. Soltz, Dale P. DeVore, Braden P. DeVore, Robert Soltz, Michael A. Soltz
-
Patent number: 5272716Abstract: A hand held laser apparatus containing a semiconductor laser diode switchably connected to a power supply. The output of the laser diode is focused and collimated by a pair of lens. Circuitry is provided to allow for either continuous wave or pulsed modes of operation as well as the capability of varying the pulsewidth of the laser. A guide laser or a light emitting diode is provided to guide the operator. The power level of the guide laser is limited so that it transfers minimal power to the workpiece but provides a visible line of laser light along which the output of the semiconductor laser diode will travel. A photodetector may be positioned between the laser diode and the lenses. Additionally, the amount of current delivered to the laser in continuous wave mode of operation or the pulse width and duty cycle of a pulse may be measured and displayed.Type: GrantFiled: October 15, 1991Date of Patent: December 21, 1993Assignee: McDonnell Douglas CorporationInventors: Barbara A. Soltz, Charles R. Chubb, James D. Cook, Thomas M. Pallett, III, Richard G. Podgornik, Dale F. Waldo
-
Patent number: 5204490Abstract: A laser diode apparatus for initiating explosives or other pyrotechnic devices that has capability of checking both the laser diode operation and the optical fiber continuity between the laser diode source and the explosives required to be detonated. Power isolation circuits are provided to control the flow of current to the laser diode, also isolation filters are used to allow only the command signals to initiate the firing circuits employed.Type: GrantFiled: June 21, 1991Date of Patent: April 20, 1993Assignee: McDonnell Douglas CorporationInventors: Barbara A. Soltz, Charles R. Chubb, John M. Haake, Richard G. Podgornik, Dale F. Waldo
-
Patent number: 5138946Abstract: A laser diode apparatus for initiating explosives or other pyrotechnic devices that has capability of checking both the laser diode operation and the optical fiber continuity between the laser diode source and the explosives required to be detonated. Power isolation circuits are provided to control the flow of current to the laser diode, also isolation filters are used to allow only the command signals to initiate the firing circuits employed.Type: GrantFiled: June 21, 1991Date of Patent: August 18, 1992Assignee: McDonnell Douglas CorporationInventors: Barbara A. Soltz, Charles R. Chubb, James D. Cook, Victor H. Nettle, Thomas M. Pallett, III, Richard G. Podgornik, Dale F. Waldo