Patents by Inventor Barbara Ann Halkier

Barbara Ann Halkier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biosynthetic engineering of glucosinolates
    Patent number: 9096863
    Abstract: The invention provides methods and materials, such as newly characterized genes, and novel processes, for converting a host from a phenotype whereby the host is unable to carry out glucosinolate (GSL) biosynthesis or chain elongation from an amino acid GSL-precursor to a phenotype whereby the host carries out said biosynthesis or elongation.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: August 4, 2015
    Assignee: University of Denmark
    Inventors: Fernando Geu Flores, Morten Thrane Nielsen, Michael Daigaard Mikkelsen, Barbara Ann Halkier, Morten Emil Møldrup
  • GLUCOSINOLATE TRANSPORTER PROTEIN AND USES THEREOF
    Publication number: 20140137294
    Abstract: Methods and means to alter the glucosinolate (GSL) content in plants, in particular in specific plant parts, by modifying glucosinolate transporter protein (GTR) activity in plants or parts thereof are herein described. In particular, methods are provided to decrease GSL content of plant seed and meal thereof, as well as methods to increase GSL content in green plant tissue, of Brassicales plants.
    Type: Application
    Filed: July 6, 2011
    Publication date: May 15, 2014
    Applicants: UNIVERSITY OF COPENHAGEN, BAYER CROPSCIENCE NV
    Inventors: Peter Denolf, Christiane Opsomer, Barbara Ann Halkier, Hussam Hassan Nour-Eldin Auis, Tonni Grube Andersen, Svend Roesen Madsen, Morten Egevang Jørgensen
  • Biosynthetic Engineering of Glucosinolates
    Publication number: 20110016582
    Abstract: The invention provides methods and materials, such as newly characterised genes, and novel processes, for converting a host from a phenotype whereby the host is unable to carry out glucosinolate (GSL) biosynthesis or chain elongation from an amino acid GSL-precursor to a phenotype whereby the host carries out said biosynthesis or elongation.
    Type: Application
    Filed: February 27, 2009
    Publication date: January 20, 2011
    Applicant: University of Copenhagen
    Inventors: Fernando Geu-Flores, Morten Thrane Nielsen, Michael Daigaard Mikkelsen, Barbara Ann Halkier, Morten Emil Moldrup
  • Cytochrome P450 monooxygenases
    Patent number: 6649814
    Abstract: Cytochrome P450II dependent monooxygenases and DNA molecules encoding these monooxygenases are provided, which are able to catalyze the biosynthethic conversion of aldoximes to nitrils and the conversion of said nitrils to the corresponding cyanohydrins, which are the presursors of cyanogenic glycosides. Moreover, the invention provides methods for obtaining DNA molecules according to the invention and methods for obtaining transgenic plants resistant to insects, acarids, or nematodes or plants with improved nutritive value.
    Type: Grant
    Filed: July 5, 2001
    Date of Patent: November 18, 2003
    Assignees: Syngenta Participations AG, Royal Veterinary and Agricultural University
    Inventors: Barbara Ann Halkier, Sören Bak, Rachel Alice Kahn, Birger Lindberg Möller
  • P450 Monooxygenases of the cyp79 family
    Publication number: 20030166202
    Abstract: The invention provides DNA coding for cytochrome P450 monooxygenases of the CYP79 family catalyzing the conversion of an aliphatic or aromatic amino acid or chain-elongated methionine homologue to the corresponding oxime. Preferred embodiments of the invention are enzymes catalyzing the conversion of L-Valine and L-Isoleucine such as the cassava enzymes CYP79D1 and CYP79D2, enzymes catalyzing the conversion of tyrosine such as the Triglochin maritima enzymes CYP79E1 and CYP79E2, enzymes catalyzing the conversion of tryptophan to the corresponding oxime indole-3-acetaldoxime such as the Arabidopsis thaliana enzyme CYP79A2 and the Brassica napus enzyme CYP79B5, and enzymes catalyzing the conversion of a chain-elongated methionine homologue such as the Arabidopsis thaliana enzymes CYP79F1 and CYP79F2. Transgenic expression of said DNA or parts thereof in plants can be used to manipulate the biosynthesis of corresponding glucosinolates or cyanogenic glucosides.
    Type: Application
    Filed: August 27, 2002
    Publication date: September 4, 2003
    Inventors: Mette Dahl Andersen, Birger Lindberg Moller, John Strikart Nielsen, Ute Wittstock, Carsten Horslev Hansen, Barbara Ann Halkier, Michael Dalgaard Mikkelsen, Peter Kamp Busk, Soren Bak
  • Cytochrome P450 monooxygenases
    Patent number: 6300544
    Abstract: Cytochrome P450II dependent monooxygenases and DNA molecules encoding these monooxygenases are provided, which are able to catalyze the biosynthetic conversion of aldoximes to nitrils and the conversion of said nitrils to the corresponding cyanohydrins, which are the precursors of cyanogenic glycosides. Moreover, the invention provides methods for obtaining DNA molecules according to the invention and methods for obtaining transgenic plants resistant to insects, acarids, or nematodes or plants with improved nutritive value.
    Type: Grant
    Filed: November 12, 1999
    Date of Patent: October 9, 2001
    Assignees: Syngenta Participations AG, Royal Veterinary and Agricultural University
    Inventors: Barbara Ann Halkier, Sören Bak, Rachel Alice Kahn, Birger Lindberg Möller
  • Cytochrome P-450 monooxygenases
    Patent number: 6133417
    Abstract: New cytochrome P-450 dependent monooxygenases and DNA molecules encoding these monooxygenases are provided, which are able to catalyze the biosynthetic pathway from amino acids to their corresponding cyanohydrins, the presursors of the cyanogenic glycosides, or to glucosinolates. Moreover, the invention provides methods for obtaining DNA molecules according to the invention and methods for obtaining transgenic plants resistant to insects, acarids, or nematodes or plants with improved nutritive value.
    Type: Grant
    Filed: February 24, 1999
    Date of Patent: October 17, 2000
    Assignees: Novartis Finance Corporation, Royal Veterinary Agricultural University
    Inventors: Birgit Maria Koch, Ole Sibbesen, Barbara Ann Halkier, Birger Lindberg M.o slashed.ller
  • Cytochrome P-450 monooxygenases
    Patent number: 5882851
    Abstract: New cytochrome P-450 dependent monooxygenases and DNA molecules encoding these monooxygenases are provided, which are able to catalyze the biosynthetic pathway from amino acids to their corresponding cyanohydrins, the presursors of the cyanogenic glycosides, or to glucosinolates. Moreover, the invention provides methods for obtaining DNA molecules according to the invention and methods for obtaining transgenic plants resistant to insects, acarids, or nematodes or plants with improved nutritive value.
    Type: Grant
    Filed: August 8, 1996
    Date of Patent: March 16, 1999
    Assignees: Novartis Finance Corporation, Royal Veterinary Agricultural University
    Inventors: Birgit Maria Koch, Ole Sibbesen, Barbara Ann Halkier, Birger Lindberg M.o slashed.ller