Patents by Inventor Barbara B. Knowles

Barbara B. Knowles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Developmental embryonic mouse cDNA libraries
    Patent number: 5789158
    Abstract: The present invention provides a number of cDNA libraries constructed from unfertilized eggs and 2-cell, 8-cell and blastocyst stage embryos, as well as a number of novel genes expressed in the 2-cell libraries.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: August 4, 1998
    Assignee: The Wistar Institute of Anatomy and Biology
    Inventors: Barbara B. Knowles, Jay L. Rothstein, Dabney Johnson, Davor Solter
  • Human hepatoma derived cell line, process for preparation thereof, and uses therefor
    Patent number: 4393133
    Abstract: Human hepatoma cell lines, useful for metabolic studies such as screening potential carcinogens and mutagens, for cultivation of viruses, and for preparation of vaccines is obtained by culturing human hepatocarcinoma or hepatoblastoma on lethally irradiated cell feeder layers in the presence of a culture medium.
    Type: Grant
    Filed: June 12, 1980
    Date of Patent: July 12, 1983
    Assignee: The Wistar Institute of Anatomy and Biology
    Inventors: Barbara B. Knowles, David P. Aden