Patents by Inventor Barbara J. Wiegel

Barbara J. Wiegel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from aspergillus nidulans
    Patent number: 4885252
    Abstract: DNA compounds and recombinant DNA expression vectors that encode and drive expression in recombinant host cells of the isopenicillin N synthetase activity of Aspergillus nidulans are useful to produce isopenicillin N synthetase and to improve the yield of .beta.-lactam-containing antibiotics from antibiotic-producing organisms. The isopenicillin N synthetase gene of A. nidulans can be isolated from plasmid pOGOO4, available from the Northern Regional Research Center under the accession number NRRL B-18171.
    Type: Grant
    Filed: December 14, 1987
    Date of Patent: December 5, 1989
    Assignee: Eli Lilly and Company
    Inventors: Thomas D. Ingolia, Stephen W. Queener, Paul L. Skatrud, Barbara J. Wiegel