Patents by Inventor Barbara Risau

Barbara Risau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Regulatory sequences capable of conferring expression of a heterologous DNA sequence in endothelial cells in vivo and uses thereof
    Patent number: 7011973
    Abstract: Described are recombinant DNA molecules comprising the regulatory sequences of an intron of the Endothelial Growth Factor (VFGF) receptor-2 gene (Flk-1) or of a gene homologous to the Flk-1 gene, being capable of conferring expression of a heterologous DNA sequence in endothelial cells, preferably in vivo. Vectors comprising said DNA molecules as well as host cells containing the same are provided. Also provided are pharmaceutical and diagnostic compositions comprising such recombinant DNA molecules and vectors. Furthermore, cells and transgenic non-human animals, comprising the aforementioned recombinant DNA molecules or vectors stably integrated into their genome and their use for the identification of substances capable of suppressing or activating transcription of a gene in endothelial cells are described.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: March 14, 2006
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.v.
    Inventors: Georg Breier, Barbara Risau, Volker Rönicke, Werner Risau
  • Regulatory sequences capable of conferring expression of a heterologous DNA sequence in endothelial cells and uses thereof
    Publication number: 20050235367
    Abstract: Described are recombinant DNA molecules comprising the regulatory sequence(s) of an intron of the Endothelial Growth Factor (VEGF) receptor-2 gene (Flk-1) or of a gene homologous to the Flk-1 gene, being capable of conferring expression of a heterologous DNA sequence in endothelial cells, preferably in vivo. Vectors comprising said DNA molecules as well as host cells containing the same are provided. Also provided are pharmaceutical and diagnostic compositions comprising such recombinant DNA molecules and vectors. Furthermore, cells and transgenic non-human animals, comprising the aforementioned recombinant DNA molecules or vectors stably integrated into their genome and their use for the identification of substances capable of suppressing or activating transcription of a gene in endothelial cells are described.
    Type: Application
    Filed: December 17, 2004
    Publication date: October 20, 2005
    Inventors: Georg Breier, Werner Risau, Volker Ronicke, Andreas Kappel, Barbara Risau