Patents by Inventor Barbro Hemmendorff

Barbro Hemmendorff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the Production of Recombinant Peptides with a Low Amount of Trisulfides
    Publication number: 20070232792
    Abstract: Methods for the production of recombinant peptides comprise fermenting cells to produce recombinant peptides. A metal salt is added to a concentrate of the fermented cells after the fermentation step, prior to peptide isolation, thereby reducing the amount of trifulsides formed in the production of the recombinant peptide. In one embodiment, the recombinant peptide is recombinant growth hormone.
    Type: Application
    Filed: May 18, 2007
    Publication date: October 4, 2007
    Inventors: Barbro Hemmendorff, Andreas Castan, Anders Persson
  • Method for the production of recombinant peptides with a low amount of trisulfides
    Patent number: 7232894
    Abstract: Methods for the production of recombinant peptides comprise fermenting cells to produce recombinant peptides. A metal salt is added to a concentrate of the fermented cells after the fermentation step, prior to peptide isolation, and the pH of the cell concentrate after the addition of the metal salt is less than or equal to 7, thereby reducing the amount of trifulsides formed in the production of the recombinant peptide, with the proviso that the production does not include conversion of formed trifulside peptide into native peptide form after the addition of the metal salt. In one embodiment, the recombinant peptide is recombinant growth hormone.
    Type: Grant
    Filed: July 5, 1999
    Date of Patent: June 19, 2007
    Assignee: Pharmacia AB
    Inventors: Barbro Hemmendorff, Andreas Castan, Anders Persson