Patents by Inventor Barney S. Graham

Barney S. Graham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of using prostacyclin to treat respiratory syncytial virus infections
    Patent number: 7132453
    Abstract: The present invention discloses methods and a kit for treating a respiratory syncytial virus infection. The method comprises providing an infection modulator, and administering a therapeutically effective amount of the infection modulator, wherein the respiratory syncytial virus infection is suppressed or precluded. The kit for suppressing a respiratory syncytial virus infection comprises an infection modulator, an applicator, and a set of instructions.
    Type: Grant
    Filed: March 14, 2003
    Date of Patent: November 7, 2006
    Assignee: Vanderbilt University
    Inventors: Ray Stokes Peebles, Jr., Koichi Hashimoto, Barney S. Graham
  • Method of using prostacyclin to treat respiratory syncytial virus infections
    Publication number: 20030216474
    Abstract: The present invention discloses methods and a kit for treating a respiratory syncytial virus infection. The method comprises providing an infection modulator, and administering a therapeutically effective amount of the infection modulator, wherein the respiratory syncytial virus infection is suppressed or precluded. The kit for suppressing a respiratory syncytial virus infection comprises an infection modulator, an applicator, and a set of instructions.
    Type: Application
    Filed: March 14, 2003
    Publication date: November 20, 2003
    Inventors: Ray Stokes Peebles, Koichi Hashimoto, Barney S. Graham
  • Interleukin-12 as an adjuvant for paramyxoviridae vaccines
    Patent number: 6071893
    Abstract: A method is disclosed of reducing viral replication of a virus of the paramyxoviridae family in a host, comprising administering to the host an antigen of the virus in combination with an effective adjuvant amount of interleukin-12 (IL-12). Human viruses of the paramyxoviridae family include paramyxoviruses (e.g., parainfluenza virus 1, parainfluenza virus 2, parainfluenza virus 3 and parainfluenza virus 4), morbilliviruses (e.g., measles virus) and pneumoviruses (e.g., respiratory syncytial virus); other non-human viruses of the paramyxoviridae family include canine distemper virus, bovine respiratory syncytial virus, Newcastle disease virus and rhinderpest virus. A composition is also disclosed comprising a mixture of an antigen of a virus of the Paramyxoviridae family and an effective adjuvant amount of interleukin-12 (IL-12).
    Type: Grant
    Filed: November 26, 1997
    Date of Patent: June 6, 2000
    Assignee: Vanderbilt University
    Inventors: Barney S. Graham, Yi-Wei Tang