Patents by Inventor Bart De Spiegeleer

Bart De Spiegeleer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230218714
    Abstract: The present invention relates to diagnostic methods to assess the presence of quorum sensing molecules (QSM), preferably peptides (QSPs), that influence muscle wasting in humans. The present invention furthermore relates to the use of the knowledge obtained by the diagnostic method in order to influence muscle wasting diseases in animals and human, by for example providing bacteria that produce beneficial QSMs or non-harmful QSMs, providing antagonists for harmful QSMs and the like.
    Type: Application
    Filed: November 6, 2020
    Publication date: July 13, 2023
    Inventors: Bart DE SPIEGELEER, Anton DE SPIEGELEER, Evelien WYNENDAELE, Dirk ELEWAUT, Nele VAN DEN NOORTGATE
  • Publication number: 20230123148
    Abstract: Quorum-sensing peptides are provided as diagnostic biomarkers, and quorum-sensing peptide inhibiting substances are provided for use in the treatment of metastasis of colorectal cancer in a subject, in particular a human subject. Methods for reducing metastasis of colorectal cancer in a subject include administering to the subject a microorganism that reduces or blocks activity of a pro-metastatic quorum-sensing peptide or a metabolite thereof present in a gastrointestinal tract or blood of the subject; and/or that reduces or blocks production of the pro-metastatic quorum-sensing peptide or the metabolite thereof in the gastrointestinal tract or blood of the subject. The pro-metastatic quorum-sensing peptide may include EntF or the metabolite EntF* of EntF.
    Type: Application
    Filed: March 26, 2021
    Publication date: April 20, 2023
    Inventors: Bart DE SPIEGELEER, Evelien WYNENDAELE, Christophe VAN DE WIELE, Olivier DE WEVER, Nathan DEBUNNE
  • Publication number: 20230089604
    Abstract: The present invention is directed to an anti-adsorption solution for the analysis of peptides. Also a process for the preparation of such an anti-adsorption solution and the use of said anti-adsorption solution are described.
    Type: Application
    Filed: September 24, 2020
    Publication date: March 23, 2023
    Applicant: Universiteit Gent
    Inventors: Bart De Spiegeleer, Frederick Verbeke, Nathalie Bracke, Evelien Wynendaele
  • Patent number: 7705000
    Abstract: The present invention relates to an oral suspension comprising meloxicam, its preparation and its use in alleviating inflammation and pain in both acute and chronic musculo-skeletal disorders.
    Type: Grant
    Filed: December 2, 2005
    Date of Patent: April 27, 2010
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Caspar Peter Elisabeth Biesmans, Bart De Spiegeleer
  • Publication number: 20090221563
    Abstract: The present invention relates to an oral suspension comprising meloxicam, its preparation and its use in alleviating inflammation and pain in both acute and chronic musculo-skeletal disorders.
    Type: Application
    Filed: December 2, 2005
    Publication date: September 3, 2009
    Inventors: Caspar Peter Elisabeth Biesmans, Bart De Spiegeleer
  • Publication number: 20060240049
    Abstract: The present invention relates to compositions suitable for oral, transdermal or parenteral (e.g. intranasal, intramuscular, subcutaneous or intravenous) administration, wherein the composition is comprised of at least one anti-protozoal agent dissolved in a mixture of an alcohol based solvent-system, an emulsifier-system and a base-system. Also provided is a method for prepraring said anti-protozoal compositions and their use in the treatment or prevention of protozoal infections in warm-blooded animals, including humans.
    Type: Application
    Filed: January 9, 2004
    Publication date: October 26, 2006
    Inventors: Bart De Spiegeleer, Hilde Dosogne