Abstract: Provided herein are methods of treating ligament flavum hypertrophy and spinal stenosis including ligament flavum hypertrophy in a patient. The method comprises delivering to cells of hypertrophic ligament flavum in a patient a pharmaceutical composition comprising micro-RNA 29a or a precursor thereof, thereby decreasing type I and/or III collagen production by the cells. Alternatively, an antisense or RNAi reagent for knocking down type I collagen and/or type III collagen expression is delivered to cells of hypertrophic ligament flavum in a patient.

Abstract: A plural component dispensing system includes a dispensing device, first and second fluid component sources, a system controller, and an operator interface device. The first fluid component source is connected to the dispensing device to deliver the first fluid component to the dispensing device. The second fluid component source is connected to the dispensing device to deliver the second fluid component to the dispensing device. The system controller is connected to regulate operation of the first fluid component source and the second fluid component source to produce a target ratio of the first fluid component and the second fluid component at the dispensing device. The operator interface device is remote from and operatively connected to the system controller. The operator interface device is configured to output system state information received from the system controller and to receive operator input to control an operational state of the system controller.

Abstract: There is provided a smart aquaculture grow out system for aquatic species, the system includes a feeder adapted to store aquafeed, the feeder comprising a feed dispensing nozzle, a feed dispenser operable to measure and project aquafeed via the feed dispensing nozzle, and a controller operatively being operable to selectively activate and deactivate the feed dispenser. A set of sensors are operable to acquire sensor data comprising water quality parameters of a pond adjacent to the feeder and images of aquatic species in the pond. A processor receives the sensor data of the grow out system, and determines, based on the sensor data of the grow out system, a metered quantity of aquafeed to provide. The processor transmits a control signal to the controller causing activation of the feed dispenser to measure and project the metered quantity of aquafeed via the feed dispensing nozzle.

Abstract: A plural component dispensing system includes a dispensing device, first and second fluid component sources, a system controller, and an operator interface device. The first fluid component source is connected to the dispensing device to deliver the first fluid component to the dispensing device. The second fluid component source is connected to the dispensing device to deliver the second fluid component to the dispensing device. The system controller is connected to regulate operation of the first fluid component source and the second fluid component source to produce a target ratio of the first fluid component and the second fluid component at the dispensing device. The operator interface device is remote from and operatively connected to the system controller. The operator interface device is configured to output system state information received from the system controller and to receive operator input to control an operational state of the system controller.

Abstract: A plural component dispensing system includes a dispensing device, first and second fluid component sources, a system controller, and an operator interface device. The first fluid component source is connected to the dispensing device to deliver the first fluid component to the dispensing device. The second fluid component source is connected to the dispensing device to deliver the second fluid component to the dispensing device. The system controller is connected to regulate operation of the first fluid component source and the second fluid component source to produce a target ratio of the first fluid component and the second fluid component at the dispensing device. The operator interface device is remote from and operatively connected to the system controller. The operator interface device is configured to output system state information received from the system controller and to receive operator input to control an operational state of the system controller.

Abstract: A fluid dispensing system includes a pump, a valve, and a dispenser disposed downstream of the valve and connected to the valve with a hose. To provide a steady flow rate at the dispenser, the pump charges the fluid to or above the pressure required to achieve a desired flow rate. The valve cycles between open and closed at a fixed frequency. The valve-open time is varied within that frequency to maintain the desired flow rate.

Abstract: A plural component dispensing system 10 receives separate fluid components, mixes the components in a predetermined ratio, and dispenses the components as mixture. Each fluid component is supplied by a separate pump 12A, 12B to an individual variably controllable fluid regulator 14A, 14B. Each fluid component is supplied from its individual fluid regulator 14A, 14B through a flow meter 18A, 18B to a mixing device 20. The ratio of the components delivered to the mixing device 20 is controlled by the individual fluid regulators 14A, 14B based upon the flow rates measured by the flow meters 18A, 18B.

Abstract: A plural component dispensing system includes a dispensing device, first and second fluid component sources, a system controller, and an operator interface device. The first fluid component source is connected to the dispensing device to deliver the first fluid component to the dispensing device. The second fluid component source is connected to the dispensing device to deliver the second fluid component to the dispensing device. The system controller is connected to regulate operation of the first fluid component source and the second fluid component source to produce a target ratio of the first fluid component and the second fluid component at the dispensing device. The operator interface device is remote from and operatively connected to the system controller. The operator interface device is configured to output system state information received from the system controller and to receive operator input to control an operational state of the system controller.

Abstract: A fluid dispensing system includes a pump, a valve, and a dispenser disposed downstream of the valve and connected to the valve with a hose. To provide a steady flow rate at the dispenser, the pump charges the fluid to or above the pressure required to achieve a desired flow rate. The valve cycles between open and closed at a fixed frequency. The valve-open time is varied within that frequency to maintain the desired flow rate.

Abstract: A method and apparatus of creating a dynamically reconfigurable energy source comprised of individual, isolated, controllable energy modules, supported by software to measure and manage the energy modules and facilitate the reconfiguration, where the platform consisting of hardware, based upon an inverted H-Bridge circuitry, in combination with software which allows for real-time management, control, and configuration of the modules and uses a combination of software algorithms and localized electronic switches, to achieve a performance and functionality of the invention matching, or exceeding, traditional large, heavy, and expensive power electronics-based products used for charging, energy storage management, power inverting, and motor or load control.

Abstract: A plural component dispensing system 10 receives separate fluid components, mixes the components in a predetermined ratio, and dispenses the components as mixture. Each fluid component is supplied by a separate pump 12A, 12B to an individual variably controllable fluid regulator 14A, 14B. Each fluid component is supplied from its individual fluid regulator 14A, 14B through a flow meter 18A, 18B to a mixing device 20. The ratio of the components delivered to the mixing device 20 is controlled by the individual fluid regulators 14A, 14B based upon the flow rates measured by the flow meters 18A, 18B.

Abstract: A method and apparatus of creating a dynamically reconfigurable energy source comprised of individual, isolated, controllable energy modules, supported by software to measure and manage the energy modules and facilitate the reconfiguration, where the platform consisting of hardware, based upon an inverted H-Bridge circuitry, in combination with software which allows for real-time management, control, and configuration of the modules and uses a combination of software algorithms and localized electronic switches, to achieve a performance and functionality of the invention matching, or exceeding, traditional large, heavy, and expensive power electronics-based products used for charging, energy storage management, power inverting, and motor or load control.

Abstract: Extruded polymer foams are prepared using brominated fatty acids, an ester, amide or ester-amide of a brominated fatty acid, a glyceride of one or more brominated fatty acids, or a polymerized brominated fatty acid as an FR additive. The brominated FR additives unexpectedly are stable at the extrusion temperatures, and provide excellent flame retardancy to the foams.

Abstract: Extruded polymer foams are prepared using brominated fatty acids, an ester, amide or ester-amide of a brominated fatty acid, a glyceride of one or more brominated fatty acids, or a polymerized brominated fatty acid as an FR additive. The brominated FR additives unexpectedly are stable at the extrusion temperatures, and provide excellent flame retardancy to the foams.

Abstract: Extruded polymer foams are prepared using brominated fatty acids, an ester, amide or ester-amide of a brominated fatty acid, a glyceride of one or more brominated fatty acids, or a polymerized brominated fatty acid as an FR additive. The brominated FR additives unexpectedly are stable at the extrusion temperatures, and provide excellent flame retardancy to the foams.

Abstract: Cushions for dynamic impact applications include anisotropic cellular polymers made in an extrusion, expanded bead or reactive foaming process. The anisotropic behavior represented by CE/CT, CV/CT and CH/CT, wherein CE, CV and CH represent the compressive strength of the cellular polymer in each of three orthogonal directions E, V and H, respectively, as measured by compressing a 25-50 mm thick sample of the cellular polymer at a strain rate of 0.08 s?1 to 25% strain, CT represents the sum of CE, CV and CH, and at least one of CE/CT, CV/CT and CH/CT has a value of at least 0.40, up to about 0.80. The cellular polymer also preferably has density of 1.75 to 2.35 pounds/cubic foot and a compressive stress in the direction of maximum compressive strength of 290-600 kPa at 25% strain when used for headliner countermeasure applications. The cushions are useful in automotive applications such as automotive headliners, door panels, knee bolsters, pillars, headrests, seat backs, load floors or instrument panels.

Abstract: Polymer foam containing styrene-acrylonitrile and containing one or more infrared attenuating agents achieves surprisingly high dimensional integrity at elevated temperatures.

Abstract: Prepare an alkenyl-aromatic foam having good surface quality, high thermal insulating properties and low density using an extrusion method by expanding a foamable polymer composition of an alkenyl-aromatic polymer composition containing less than 20 weight-percent covalently bonded halogens and having a polydispersity of less than 2.5 and a water solubility greater than 0.09 moles per kilogram and 2.2 moles per kilogram or less at 130 degrees Celsius and 101 kilopascals pressure and 0.8-2 moles per kilogram of a blowing agent containing 0.4 moles per kilogram or more of a chlorine-free fluorinated blowing agents and water at a concentration of at least 0.22 moles per kilogram; wherein moles per kilogram are relative to kilograms of alkenyl-aromatic polymer. The resulting foam has a density of 64 kilograms per cubic meter or less and a thermal conductivity of 32 milliwatts per meter-Kelvin or less after 180 days.

Abstract: Extruded polymer foams are prepared using brominated fatty acids, an ester, amide or ester-amide of a brominated fatty acid, a glyceride of one or more brominated fatty acids, or a polymerized brominated fatty acid as an FR additive. The brominated FR additives unexpectedly are stable at the extrusion temperatures, and provide excellent flame retardancy to the foams.

Abstract: The invention is an energy absorbing member comprising, an amorphous thermoplastic cellular polymer in contact with a structural element, wherein at least about 50% of the cells of the amorphous cellular polymer are closed cells and the closed cells have a gas pressure that is about 0.5 atmosphere to about 1.4 atmospheres at ambient temperature.