Patents by Inventor Becky M. Hess

Becky M. Hess has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spent enrichment media for growth of gene-matched microorganisms
    Patent number: 11104966
    Abstract: A method for amplifying and detecting microorganisms, such as species of Listeria, is described. The method utilizes gene-matched enrichment media and PCR-based detection. The enrichment media is spent media produced using a modified microorganism containing a plurality of mutations in a selected gene such that the modified microorganism does not contain the PCR signature. Thus, PCR detects only the amplified microorganism of interest, not the modified microorganism. Exemplary methods and kits for amplification and detection of Listeria species are described.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: August 31, 2021
    Assignee: Battelle Memorial Institute
    Inventors: Richard M. Ozanich, Janine R. Hutchison, Kristin D. Victry, Becky M. Hess
  • GENE-MATCHED ENRICHMENT AND POLYMERASE CHAIN REACTION FOR RAPID DETECTION OF MICROORGANISMS
    Publication number: 20190002962
    Abstract: A method for amplifying and detecting microorganisms, such as species of Listeria, is described. The method utilizes gene-matched enrichment media and PCR-based detection. The enrichment media is spent media produced using a modified microorganism containing a plurality of mutations in a selected gene such that the modified microorganism does not contain the PCR signature. Thus, PCR detects only the amplified microorganism of interest, not the modified microorganism. Exemplary methods and kits for amplification and detection of Listeria species are described.
    Type: Application
    Filed: September 14, 2018
    Publication date: January 3, 2019
    Applicant: Battelle Memorial Institute
    Inventors: Richard M. Ozanich, Janine R. Hutchison, Kristin D. Victry, Becky M. Hess
  • Gene-matched enrichment and polymerase chain reaction for rapid detection of microorganisms
    Patent number: 10100369
    Abstract: A method for amplifying and detecting microorganisms, such as species of Listeria, is described. The method utilizes gene-matched enrichment media and PCR-based detection. The enrichment media is spent media produced using a modified microorganism containing a plurality of mutations in a selected gene such that the modified microorganism does not contain the PCR signature. Thus, PCR detects only the amplified microorganism of interest, not the modified microorganism. Exemplary methods and kits for amplification and detection of Listeria species are described.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: October 16, 2018
    Assignee: Battelle Memorial Institute
    Inventors: Richard M. Ozanich, Janine R. Hutchison, Kristin D. Victry, Becky M. Hess
  • ORGANOTYPIC LUNG MODEL WITH FUNCTIONAL IMMUNE CELLS
    Publication number: 20180119091
    Abstract: A three dimensional in vitro co-culture system is provided for determining a pathogen's interaction with immune cells differentiated from healthy tissues and grown at air-liquid interface with epithelial cells. Also provided are methods of producing the three dimensional in vitro co-culture system. The system provides a way to assess predictive pathogenicity and threat, and develop medical countermeasures.
    Type: Application
    Filed: October 31, 2017
    Publication date: May 3, 2018
    Inventors: Becky M. Hess, Thomas J. Weber