Abstract: According to implementations of the subject matter described herein, there is provided a solution for generating a video from an image. In this solution, an input image and a reference video are obtained; a motion pattern of a reference object in the reference video is determined based on the reference video. An output video with the input image as a starting frame is generated. Motion of a target object in the output video has the motion pattern of the reference object and the target object is in the input image. In this way, according to the solution, the motion pattern of the reference object in the reference video can be intuitively applied to the input image to generate the output video, and the motion of the target object in the output video has the motion pattern of the reference object.

Abstract: The present disclosure relates to a game interactive control method and apparatus, a storage medium and an electronic device, and relates to the technical field of computers. According to the method, by determining the game intention of the agent according to the game state information, and inputting the game state information, the game communication information and the game intention into the communication prediction model, the target communication content corresponding to the agent is obtained, and then the target communication content is outputted, so that the player character determines a game action to be executed by the agent based on the target communication content. This can not only improve the gaming activity when the real player is battling against the agent, but also enable the real player to know the game intention of the agent so as to cooperate with the agent and improve the gaming quality.

Abstract: A method, apparatus, electronic device and storage medium for combat control are provided. The method comprising: determining, according to current game status data and communication information of the target object, a communicated strategic intention of a target object, wherein the communicated strategic intention characterizes a combat target expressed by the communication information; determining, according to the game status data, an initial strategic intention of a virtual object in response to the game state data; determining, according to the initial strategic intention and the communicated strategic intention, the target strategic intention of the virtual object; determining a response action of the virtual object based on the target strategic intention, and controlling the virtual object to perform the response action.

Abstract: Related to are a method and apparatus for game role interaction control, a storage medium, and an electronic device. In the method, a target communication period of an intelligent agent may be dynamically adjusted by the current signal communication information triggered by a game match and the current game state information of the game match, to adjust the frequency of the intelligent agent for sending communication messages in the game match. Therefore, in the case of active communication of real players, the intelligent agent can be prevented from frequently sending communication messages, resulting in a conflict with the communication messages of the real players, and the interference of excessive communication messages on the real players can also be prevented. Moreover, in the case of no communication of the real players, the communication willingness of the real players can be motivated, thereby ensuring a good battle atmosphere for the game match.

Abstract: The present disclosure relates to the technical field of computers, and in particular to a game character control method and apparatus, a storage medium and an electronic device. In the method, game state information of a game match is adjusted according to game alignments to which an intelligent agent and a player character belong, so as to obtain target state information, a target game intention of the intelligent agent is determined according to the target state information, then a target operation of the intelligent agent in the game match is determined according to the target state information and the target game intention, and the target operation executed by the intelligent agent may be adjusted according to different game situations, so that the intelligent agent can flexibly adjust game actions to provide different playing methods in a human-computer battle.

Abstract: Provided are fusion proteins that include an apolipoprotein B mRNA editing enzyme catalytic subunit 3A (APOBEC3A) and a clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas) protein, optionally further with uracil glycosylase inhibitor (UGI). Such a fusion protein is able to conduct base editing in DNA by deaminating cytosine to uracil, even when the cytosine is in a GpC context or is methylated.

Abstract: A method and system for transforming an input image via a plurality of image transformation stylizers includes receiving the input image; providing the input image, information about the plurality of image transformation stylizers and at least one of user data, history data, and contextual data to a trained machine-learning (ML) model for selecting a subset of the plurality of image transformation stylizers; receiving as an output from the ML model the subset of image transformation stylizers; executing the subset of the image transformation stylizers on the input image to generate a plurality of transformed output images; ranking the plurality of transformed output images based on at least one of the input image, the user data, the history data, and the contextual data; and providing the ranked plurality of transformed output images for display.

Abstract: Provided are fusion proteins that include an apolipoprotein B mRNA editing enzyme catalytic subunit 3A (APOBEC3A) and a clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas) protein, optionally further with uracil glycosylase inhibitor (UGI). Such a fusion protein is able to conduct base editing in DNA by deaminating cytosine to uracil, even when the cytosine is in a GpC context or is methylated.

Abstract: Provided are fusion proteins and related molecules useful for conducting base editing with reduced or no off-target mutations. The fusion protein may include a first fragment comprising a nucleobase deaminase or a catalytic domain thereof, a second fragment comprising a nucleobase deaminase inhibitor, and a protease cleavage site between the first fragment and the second fragment. Also provided are improved prime editing systems, including prime editing guide RNA with improved stability.

Abstract: Provided are compositions and methods for enhanced prime editing, which include a pegRNA that encodes a target mutation in a target protein, along with one or more nearby silent or conservative mutations. These silent mutations can increase the editing efficiency, without causing a change to the target protein sequence. Also provided are compositions and methods of using the improved prime editing for preventing or treating infections by SARS-CoV or SARS-CoV-2.

Abstract: Provided are fusion proteins and related molecules useful for conducting base editing with reduced or no off-target mutations. The fusion protein may include a first fragment comprising a nucleobase deaminase or a catalytic domain thereof, a second fragment comprising a nucleobase deaminase inhibitor, and a protease cleavage site between the first fragment and the second fragment. Also provided are improved prime editing systems, including prime editing guide RNA with improved stability.

Abstract: Provided are fusion proteins and related molecules useful for conducting base editing with reduced or no off-target mutations. The fusion protein may include a first fragment comprising a nucleobase deaminase or a catalytic domain thereof, a second fragment comprising a nucleobase deaminase inhibitor, and a protease cleavage site between the first fragment and the second fragment. Also provided are improved prime editing systems, including prime editing guide RNA with improved stability.

Abstract: Provided are fusion proteins and related molecules useful for conducting base editing with reduced or no off-target mutations. The fusion proteins may include a first fragment comprising a nucleobase deaminase or a catalytic domain thereof, a second fragment comprising a nucleobase deaminase inhibitory domain, and a protease cleavage site between the first fragment and the second fragment. Also provided are improved prime editing systems, including prime editing guide RNA with improved stability.

Abstract: Provided are fusion proteins and related molecules useful for conducting base editing with reduced or no off-target mutations. The fusion proteins may include a first fragment comprising a nucleobase deaminase or a catalytic domain thereof, a second fragment comprising a nucleobase deaminase inhibitory domain, and a protease cleavage site between the first fragment and the second fragment. Also provided are improved prime editing systems, including prime editing guide RNA with improved stability.

Abstract: Provided are fusion proteins that include an apolipoprotein B mRNA editing enzyme catalytic subunit 3A (APOBEC3A) and a clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas) protein, optionally further with uracil glycosylase inhibitor (UGI). Such a fusion protein is able to conduct base editing in DNA by deaminating cytosine to uracil, even when the cytosine is in a GpC context or is methylated.

Abstract: In an approach to predicting issue development trends based on generated ordered association rules, one or more computer processors subdivide an issue into a set of one or more subproblems. The one or more computer processors generate ordered association rules by inputting the set of one or more subproblems into a model trained with historical subproblems, historical solutions, and historical ordered association rules. The one or more computer processors determine one or more solutions for each subproblem in the set of one or more subproblems utilizing the generated ordered association rules. The one or more computer processors present the one or more determined solutions.

Abstract: Provided are base editors containing a cytidine and a catalytically inactive version of Lachnospiraceae bacterium Cpf1 (LbCpf1). The new base editors have greatly improved editing efficiency and fidelity as compared to Cas9-based base editors, and have different editing windows.

Abstract: An information processing method, which is applied to a server, includes: a public message is transmitted to a first client, the public message being a message issued to the first client by the server, the public message carrying first information and a second information set including N pieces of second information, with N being a positive integer, the first information is information only allowed to be gotten by the first client and the second information is information only allowed to be gotten by a client in a sharing relationship with the first client; and a request for getting the second information is received from a second client, it is verified whether the second client is in the sharing relationship with the first client, and after the second client is determined to be in the sharing relationship with the first client, the second client is allowed to get the second information.

Abstract: The present application relates generally to a projection system and method for projecting content onto a moving performer. In one embodiment, the system includes a projector that projects light onto the performer, a position sensor, such as a camera and/or depth sensor that captures position information about the performer, and a computer that modifies original content based on the position information of the performer. The computer uses the position information to generate a mask, such as a silhouette, of the performer, and then modifies the original content based on the mask of the performer. The modified content is then projected by the projector onto the performer.

Abstract: Embodiments of the present disclosure provide a temperature compensation circuit, a display panel and a temperature compensation method. The temperature compensation circuit comprises: a temperature sensing unit, adapted to sense a temperature of an external environment; a temperature compensation control unit being adapted to compare the temperature sensed output voltage with a reference voltage, and generate a control signal based on the comparison result; and a first voltage source adapted to receive a control signal from the temperature compensation control unit, generate a corresponding driving voltage based on the control signal and output the corresponding driving voltage to a gate drive circuit as a gate driving voltage of the gate drive circuit, and generate a feedback signal according to the control signal and output the feedback signal to the temperature sensing unit and the temperature compensation control unit, the reference voltage being variable based on the feedback signal.