Patents by Inventor Bellamkonda K. Kishore

Bellamkonda K. Kishore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF KIDNEY DISEASES ASSOCIATED WITH ELEVATED AVP
    Publication number: 20220270454
    Abstract: Disclosed are the methods for treating kidney disease including autosomal dominant polycystic kidney disease (ADPKD) in a subject, comprising the step of administering to the subject a composition comprising a therapeutically effective amount of ticagrelor or a derivative thereof, treating ADPKD. Disclosed are methods of decreasing arginine vasopressin (AVP) production in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production. Disclosed are methods for treating dilutional hyponatremia in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production.
    Type: Application
    Filed: May 2, 2022
    Publication date: August 25, 2022
    Inventors: Bellamkonda K. Kishore, Yue Zhang, Noel G. Carlson
  • Treatment of kidney diseases associated with elevated AVP
    Patent number: 11354990
    Abstract: Disclosed are methods for treating kidney disease including autosomal dominant polycystic kidney disease (ADPKD) in a subject, comprising the step of administering to the subject a composition comprising a therapeutically effective amount of ticagrelor or a derivative thereof, thereby treating ADPKD. Disclosed are methods of decreasing arginine vasopressin (AVP) production in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production. Disclosed are methods for treating dilutional hyponatremia in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production.
    Type: Grant
    Filed: April 6, 2020
    Date of Patent: June 7, 2022
    Inventors: Bellamkonda K. Kishore, Yue Zhang, Noel G. Carlson
  • TREATMENT OF KIDNEY DISEASES ASSOCIATED WITH ELEVATED AVP
    Publication number: 20200234552
    Abstract: Disclosed are methods for treating kidney disease including autosomal dominant polycystic kidney disease (ADPKD) in a subject, comprising the step of administering to the subject a composition comprising a therapeutically effective amount of ticagrelor or a derivative thereof, thereby treating ADPKD. Disclosed are methods of decreasing arginine vasopressin (AVP) production in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production. Disclosed are methods for treating dilutional hyponatremia in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production.
    Type: Application
    Filed: April 6, 2020
    Publication date: July 23, 2020
    Inventors: BELLAMKONDA K. KISHORE, Yue Zhang, Noel G. Carlson
  • Treatment of kidney diseases associated with elevated AVP
    Patent number: 10614684
    Abstract: Disclosed are methods for treating kidney disease including autosomal dominant polycystic kidney disease (ADPKD) in a subject, comprising the step of administering to the subject a composition comprising a therapeutically effective amount of ticagrelor or a derivative thereof, thereby treating ADPKD. Disclosed are methods of decreasing arginine vasopressin (AVP) production in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production. Disclosed are methods for treating dilutional hyponatremia in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: April 7, 2020
    Assignee: THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE
    Inventors: Bellamkonda K. Kishore, Yue Zhang, Noel G. Carlson
  • Composition and methods for the prevention and treatment of diet-induced obesity
    Patent number: 10107795
    Abstract: Blunting the activity of the P2Y2 receptor results in a resistance to diet-induced obesity, an increased metabolic rate, and a better glucose tolerance. Compounds that inhibit the puringeric P2Y2 receptor are useful for treating disorders associated with diabetes, treating obesity, and increasing metabolism (e.g., fatty acid metabolism).
    Type: Grant
    Filed: October 25, 2013
    Date of Patent: October 23, 2018
    Assignee: The United States of America as represented by the Department of Veterans Affairs
    Inventors: Bellamkonda K. Kishore, Yue Zhang, Carolyn M. Ecelbarger
  • TREATMENT OF KIDNEY DISEASES ASSOCIATED WITH ELEVATED AVP
    Publication number: 20180214450
    Abstract: Disclosed are methods for treating kidney disease including autosomal dominant polycystic kidney disease (ADPKD) in a subject, comprising the step of administering to the subject a composition comprising a therapeutically effective amount of ticagrelor or a derivative thereof, thereby treating ADPKD. Disclosed are methods of decreasing arginine vasopressin (AVP) production in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production. Disclosed are methods for treating dilutional hyponatremia in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production.
    Type: Application
    Filed: January 31, 2018
    Publication date: August 2, 2018
    Inventors: Bellamkonda K. Kishore, Yue Zhang, Noel G. Carlson
  • Methods for treating diet-induced obesity by decreasing or inhibiting P2Y2 purinergic receptor expression or activity
    Patent number: 10024846
    Abstract: The invention provides a method for treating or preventing diet-induced obesity in a subject comprising administering an agent in an effective amount so that expression or activity of the P2Y2 receptor is decreased or inhibited in the subject thereby treating or preventing diet-induced obesity in the subject.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: July 17, 2018
    Assignee: The United States of America as represented by the Department of Veterans Affairs
    Inventors: Bellamkonda K. Kishore, Yue Zhang, Carolyn M. Ecelbarger
  • Methods and compositions for treating nephrogenic diabetes insipidus
    Patent number: 9913831
    Abstract: Disclosed is a treatment of diabetes insipidus. Methods of treating diabetes insipidus disorders associated with P2Y receptors using the compounds and compositions are also disclosed.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: March 13, 2018
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Bellamkonda K. Kishore, Noel G. Carlson, Yue Zhang
  • Methods and compositions for treating nephrogenic diabetes insipidus
    Patent number: 9901624
    Abstract: Disclosed are compositions and methods for treating nephrogenic diabetes insipidus and for induction of diuretic effect.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: February 27, 2018
    Assignees: The United States of America as represented by the Department of Veterans Affairs, The University of Utah
    Inventors: Bellamkonda K. Kishore, Noel G. Carlson, Donald E. Kohan, Raoul D. Nelson
  • METHODS AND COMPOSITIONS FOR TREATING NEPHROGENIC DIABETES INSIPIDUS
    Publication number: 20170035859
    Abstract: Disclosed are compositions and methods for treating nephrogenic diabetes insipidus and for induction of diuretic effect.
    Type: Application
    Filed: June 16, 2014
    Publication date: February 9, 2017
    Inventors: Bellamkonda K. Kishore, Noel G. Carlson, Donald E. Kohan, Raoul D. Nelson
  • Methods and compositions for treating nephrogenic diabetes insipidus
    Patent number: 9539246
    Abstract: Disclosed is a treatment of diabetes insipidus. Methods of treating diabetes insipidus disorders associated with P2Y receptors using the compounds and compositions are also disclosed.
    Type: Grant
    Filed: August 29, 2012
    Date of Patent: January 10, 2017
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Bellamkonda K. Kishore, Noel G. Carlson, Yue Zhang
  • COMPOSITION AND METHODS FOR THE PREVENTION AND TREATMENT OF DIET-INDUCED OBESITY
    Publication number: 20160377598
    Abstract: The invention provides a method for treating or preventing diet-induced obesity in a subject comprising administering an agent in an effective amount so that expression or activity of the P2Y2 receptor is decreased or inhibited in the subject thereby treating or preventing diet-induced obesity in the subject.
    Type: Application
    Filed: April 27, 2015
    Publication date: December 29, 2016
    Inventors: Bellamkonda K. Kishore, Yue Zhang, Carolyn M. Ecelbarger
  • METHODS AND COMPOSITIONS FOR TREATING NEPHROGENIC DIABETES INSIPIDUS
    Publication number: 20160296504
    Abstract: Disclosed is a treatment of diabetes insipidus. Methods of treating diabetes insipidus disorders associated with P2Y receptors using the compounds and compositions are also disclosed.
    Type: Application
    Filed: June 16, 2016
    Publication date: October 13, 2016
    Inventors: Bellamkonda K. Kishore, Noel G. Carlson, Yue Zhang
  • COMPOSITION AND METHODS FOR THE PREVENTION AND TREATMENT OF DIET-INDUCED OBESITY
    Publication number: 20150259692
    Abstract: Blunting the activity of the P2Y2 receptor results in a resistance to diet-induced obesity, an increased metabolic rate, and a better glucose tolerance. Compounds that inhibit the puringeric P2Y2 receptor are useful for treating disorders associated with diabetes, treating obesity, and increasing metabolism (e.g., fatty acid metabolism).
    Type: Application
    Filed: October 25, 2013
    Publication date: September 17, 2015
    Inventors: Bellamkonda K. Kishore, Yue Zhang, Carolyn M. Ecelbarger
  • METHODS AND COMPOSITIONS FOR TREATING NEPHROGENIC DIABETES INSIPIDUS
    Publication number: 20140377380
    Abstract: Disclosed is a treatment of diabetes insipidus. Methods of treating diabetes insipidus disorders associated with P2Y receptors using the compounds and compositions are also disclosed.
    Type: Application
    Filed: August 29, 2012
    Publication date: December 25, 2014
    Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Bellamkonda K. Kishore, Noel G. Carlson, Yue Zhang
  • Methods and compositions for treating nephrogenic diabetes and insipidus
    Publication number: 20090297497
    Abstract: Disclosed are compositions and methods for treating nephrogenic diabetes insipidus and for induction of diuretic effect.
    Type: Application
    Filed: October 21, 2005
    Publication date: December 3, 2009
    Inventors: Bellamkonda K. Kishore, Noel G. Carlson, Donald E. Kohan, Raoul D. Nelson