Patents by Inventor Ben Hause

Ben Hause has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240091336
    Abstract: Immunogenic compositions for inducing a universal immune response to influenza, and particularly influenza A, by eliciting anti-neuraminidase antibodies which provide protection against heterologous influenza infection. Compositions comprising recombinant expression vectors expressing neuraminidase in cultured cells dispersed in a pharmaceutically-acceptable carrier comprising cell culture media, and optional adjuvant. Methods of inducing immune responses against influenza, and particularly influenza A, by eliciting anti-neuraminidase antibodies in a host animal susceptible to infection.
    Type: Application
    Filed: September 29, 2023
    Publication date: March 21, 2024
    Inventor: Ben Hause
  • Publication number: 20240092838
    Abstract: A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analyses suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
    Type: Application
    Filed: September 5, 2023
    Publication date: March 21, 2024
    Inventor: Ben Hause
  • Patent number: 11780889
    Abstract: A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analyses suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
    Type: Grant
    Filed: April 8, 2022
    Date of Patent: October 10, 2023
    Assignee: Kansas State University Research Foundation
    Inventor: Ben Hause
  • Patent number: 11780887
    Abstract: A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analyses suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
    Type: Grant
    Filed: February 19, 2021
    Date of Patent: October 10, 2023
    Assignee: Kansas State University Research Foundation
    Inventor: Ben Hause
  • Patent number: 11771756
    Abstract: Immunogenic compositions for inducing a universal immune response to influenza, and particularly influenza A, by eliciting anti-neuraminidase antibodies which provide protection against heterologous influenza infection. Compositions comprising recombinant baculovirus expression vectors expressing neuraminidase in cultured insect cells dispersed in a pharmaceutically-acceptable carrier comprising insect cell culture media, and optional adjuvant. Methods of inducing immune responses against influenza, and particularly influenza A, by eliciting anti-neuraminidase antibodies in a host animal susceptible to infection.
    Type: Grant
    Filed: May 23, 2022
    Date of Patent: October 3, 2023
    Assignee: Cambridge Technologies LLC
    Inventor: Ben Hause
  • Publication number: 20220354950
    Abstract: A prophylactic and/or therapeutic food composition for control of bacterial and/or fungal infection in bees and/or bee larvae, and methods of using and making the same. Bee feed compositions comprising bacterial and/or fungal antibodies dispersed in an edible base composition. Use of bacterial and/or fungal antigenic agents to passively generate bacterial and/or fungal antibodies in chicken egg yolks, and use of such bacterial and/or fungal antibodies for prophylaxis or treatment of bacterial and/or fungal infection in the bees and/or larvae.
    Type: Application
    Filed: October 22, 2020
    Publication date: November 10, 2022
    Inventor: Ben Hause
  • Publication number: 20220296698
    Abstract: Immunogenic compositions for inducing a universal immune response to influenza, and particularly influenza A, by eliciting anti-neuraminidase antibodies which provide protection against heterologous influenza infection. Compositions comprising recombinant baculovirus expression vectors expressing neuraminidase in cultured insect cells dispersed in a pharmaceutically-acceptable carrier comprising insect cell culture media, and optional adjuvant. Methods of inducing immune responses against influenza, and particularly influenza A, by eliciting anti-neuraminidase antibodies in a host animal susceptible to infection.
    Type: Application
    Filed: May 23, 2022
    Publication date: September 22, 2022
    Inventor: Ben Hause
  • Publication number: 20220251144
    Abstract: A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analyses suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
    Type: Application
    Filed: April 8, 2022
    Publication date: August 11, 2022
    Inventor: Ben Hause
  • Patent number: 11351241
    Abstract: Immunogenic compositions for inducing a universal immune response to influenza, and particularly influenza A, by eliciting anti-neuraminidase antibodies which provide protection against heterologous influenza infection. Compositions comprising recombinant baculovirus expression vectors expressing neuraminidase in cultured insect cells dispersed in a pharmaceutically-acceptable carrier comprising insect cell culture media, and optional adjuvant. Methods of inducing immune responses against influenza, and particularly influenza A, by eliciting anti-neuraminidase antibodies in a host animal susceptible to infection.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: June 7, 2022
    Assignee: Cambridge Technologies LLC
    Inventor: Ben Hause
  • Publication number: 20220125073
    Abstract: A prophylactic and/or therapeutic food composition for control of deformed wing vims (DWV) in bees and/or bee larvae, and methods of using and making the same. Bee feed compositions comprising anti-DWV antibodies dispersed in an edible base composition. Use of recombinant VP1, VP2, VP3, and/or VP4 capsid proteins, or VLPs of deformed wing vims (DWV) to passively generate anti-DWV antibodies in chicken egg yolks, and use of such anti-DWV antibodies for prophylaxis or treatment of deformed wing virus in the bees and/or larvae.
    Type: Application
    Filed: September 20, 2019
    Publication date: April 28, 2022
    Inventor: Ben Hause
  • Patent number: 11090378
    Abstract: The present disclosure provides the complete nucleotide sequence for porcine parainfluenza virus 1. Immunogenic compositions comprising portions of the nucleotide sequence and proteins expressed therefrom are also provided.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: August 17, 2021
    Assignee: Kansas State University Research Foundation
    Inventor: Ben Hause
  • Publication number: 20210188919
    Abstract: A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analyses suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
    Type: Application
    Filed: February 19, 2021
    Publication date: June 24, 2021
    Inventor: Ben Hause
  • Patent number: 10954274
    Abstract: A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analyses suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: March 23, 2021
    Assignee: Kansas State University Research Foundation
    Inventor: Ben Hause
  • Publication number: 20200261566
    Abstract: The present disclosure provides the complete nucleotide sequence for porcine parainfluenza virus 1. Immunogenic compositions comprising portions of the nucleotide sequence and proteins expressed therefrom are also provided.
    Type: Application
    Filed: January 4, 2017
    Publication date: August 20, 2020
    Inventor: Ben Hause
  • Publication number: 20200188505
    Abstract: Immunogenic compositions for inducing a universal immune response to influenza, and particularly influenza A, by eliciting anti-neuraminidase antibodies which provide protection against heterologous influenza infection. Compositions comprising recombinant baculovirus expression vectors expressing neuraminidase in cultured insect cells dispersed in a pharmaceutically-acceptable carrier comprising insect cell culture media, and optional adjuvant. Methods of inducing immune responses against influenza, and particularly influenza A, by eliciting anti-neuraminidase antibodies in a host animal susceptible to infection.
    Type: Application
    Filed: December 12, 2019
    Publication date: June 18, 2020
    Inventor: Ben Hause
  • Patent number: 10555995
    Abstract: Porcine pestivirus designated herein as atypical porcine pestivirus (“APPV”) (Genbank accession no. KR011347.1). Immunogenic compositions to induce an immune response against porcine pestivirus infection in a pig are described, which APPV antigenic agents (e.g., isolated whole virus, derivatives thereof, functional fragments thereof, and combinations of the foregoing). Methods of vaccinating against porcine pestivirus infection using the immunogenic compositions are also described. The methods can be also applied for clinical research and/or study, including diagnostic methods for detecting pestivirus infection using monoclonal antibodies specifically binding to APPV epitopes.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: February 11, 2020
    Assignee: Kansas State University Research Foundation
    Inventors: Ben Hause, Emily Collin, Ying Fang, Lalitha Peddireddi
  • Publication number: 20200031876
    Abstract: A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analyses suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
    Type: Application
    Filed: October 11, 2019
    Publication date: January 30, 2020
    Inventor: Ben Hause
  • Patent number: 10450351
    Abstract: A new species of circovirus, porcine circovirus type 3 (PCV3), was identified from sows with clinical symptoms normally associated with porcine circovirus type 2 (PCV2) infection and in aborted fetuses. Molecular and serological analysis suggest PCV3 commonly circulates in U.S. swine. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: October 22, 2019
    Assignee: Kansas State University Research Foundation
    Inventor: Ben Hause
  • Publication number: 20180326040
    Abstract: Attenuated live or replication-deficient chimeric swine influenza virus vaccine, and a platform to develop a multitude of other vaccines in swine and other species. The chimeric influenza virus A comprises a backbone of viral genomic segments derived from influenza A, and expresses a heterologous surface protein (influenza D hemagglutinin esterase fusion protein), and optionally at least one other heterologous protein, such as an antigenic component of a target pathogen.
    Type: Application
    Filed: November 16, 2016
    Publication date: November 15, 2018
    Inventors: Ben Hause, Emily Collin
  • Publication number: 20180303926
    Abstract: Porcine pestivirus designated herein as atypical porcine pestivirus (“APPV”) (Genbank accession no. KR011347.1). Immunogenic compositions to induce an immune response against porcine pestivirus infection in a pig are described, which APPV antigenic agents (e.g., isolated whole virus, derivatives thereof, functional fragments thereof, and combinations of the foregoing). Methods of vaccinating against porcine pestivirus infection using the immunogenic compositions are also described. The methods can be also applied for clinical research and/or study, including diagnostic methods for detecting pestivirus infection using monoclonal antibodies specifically binding to APPV epitopes.
    Type: Application
    Filed: April 29, 2016
    Publication date: October 25, 2018
    Inventors: Ben Hause, Emily Collin, Ying Fang, Lalitha Peddireddi