Patents by Inventor Ben Hsieh
Ben Hsieh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190090859Abstract: A urine capturing arrangement is configured to receive urine from a user of a toilet, and a chamber is fluidically coupled to the capturing arrangement. A diverter is fluidically coupled between the capturing arrangement and the chamber. The diverter is configured to divert a volume of the received urine to the chamber. A detection unit is configured to sense for presence of a predetermined characteristic in the volume of the urine and to generate at least one electrical signal comprising information about the predetermined characteristic.Type: ApplicationFiled: November 27, 2018Publication date: March 28, 2019Inventors: Michael I. Recht, Joerg Martini, Abhishek Ramkumar, Peter Kiesel, Ben Hsieh, Eugene M. Chow
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Publication number: 20150359522Abstract: A urine capturing arrangement is configured to receive urine from a user of a toilet, and a chamber is fluidically coupled to the capturing arrangement. A diverter is fluidically coupled between the capturing arrangement and the chamber. The diverter is configured to divert a volume of the received urine to the chamber. A detection unit is configured to sense for presence of a predetermined characteristic in the volume of the urine and to generate at least one electrical signal comprising information about the predetermined characteristic.Type: ApplicationFiled: June 17, 2014Publication date: December 17, 2015Inventors: Michael I. Recht, Joerg Martini, Abhishek Ramkumar, Peter Kiesel, Ben Hsieh, Eugene M. Chow
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Patent number: 8268169Abstract: The water treatment system and method incorporating the use of a hydrodynamic separator to remove most of the total suspended solids (TSS) in source water being treated to thereby lighten the load on membrane filtration in the water treatment system and lower energy costs.Type: GrantFiled: December 20, 2010Date of Patent: September 18, 2012Assignee: Palo Alto Research Center IncorporatedInventors: Meng H. Lean, Joe Zuback, Nitin Parekh, Norine E. Chang, Huangpin Ben Hsieh, Kai Melde
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Publication number: 20120152814Abstract: The water treatment system and method incorporating the use of a hydrodynamic separator to remove most of the total suspended solids (TSS) in source water being treated to thereby lighten the load on membrane filtration in the water treatment system and lower energy costs.Type: ApplicationFiled: December 20, 2010Publication date: June 21, 2012Applicant: PALO ALTO RESEARCH CENTER INCORPORATEDInventors: Meng H. Lean, Joe Zuback, Nitin Parekh, Norine E. Chang, Huangpin Ben Hsieh, Kai Melde
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Publication number: 20120074074Abstract: A self-cleaning screen system and method removes contaminants from a fluid passed through a screen of the self-cleaning screen system. The self-cleaning screen system includes a cleaning mechanism used to remove contaminants which may have adhered to the screen. The self-cleaning screen system is self-powered by extracting energy from the fluid flow to cause rotation or other movement of either the screen and/or the cleaning mechanism.Type: ApplicationFiled: September 24, 2010Publication date: March 29, 2012Applicant: Palo Alto Research Center IncorporatedInventors: Meng H. Lean, Armin R. Völkel, Ashutosh Kole, Kai Melde, Huangpin Ben Hsieh
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Patent number: 7842465Abstract: A method is provided for preparing a sample containing potential cells of interest and of using a laser of a laser based system for novel excitation and emission collection, and data usage including use of obtained data for direct and ratio based measurements. The prepared sample is configured to emit signals having spectral characteristics sufficient to permit filtering to differentiate and eliminate most false positives from true positives among acquired imaging events, in an imaging system employing a laser spot having a range of diameters from 1 to 20 ?m or greater and which excites the fluorescence in a conventional or novel manner. These filtered events may be subsequently imaged and confirmed with another higher resolution device such as a fluorescent microscope in a short amount of time.Type: GrantFiled: January 17, 2006Date of Patent: November 30, 2010Assignee: Palo Alto Research Center IncorporatedInventors: Huangpin Ben Hsieh, Nicole H. Lazarus, Robert T. Krivacic, Douglas N. Curry, Richard H. Bruce
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Patent number: 7811438Abstract: A flow cell is disclosed for collecting and concentrating a sample dispersed in a flowing medium. The collected sample can be selectively manipulated within the cell by the use of one or more traveling wave grids. The cells are particularly useful as bio-enrichment devices and can be utilized upstream of conventional analytical or detection instruments.Type: GrantFiled: December 8, 2004Date of Patent: October 12, 2010Assignee: Palo Alto Research Center IncorporatedInventors: Meng H. Lean, Armin R. Völkel, Peter Kiesel, Oliver Schmidt, Noble M. Johnson, H. Ben Hsieh
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Publication number: 20100196914Abstract: Disclosed is a method using a large area flat panel imager which is specifically adapted for rare cell detection methods. The method generally includes an imager having a sample receiving surface which can provide a digital or electronic image of a sample deposited on the surface. The method also includes a selectively positionable microscope and/or camera which are used to obtain high resolution images of the deposited samples. An electronic controller can also be used in conjunction with the imager, microscope, and/or camera to selectively position at least one of those components to focus on desired regions of the deposited sample. The noted method is particularly adapted for use with chemiluminescence or other tagging technologies.Type: ApplicationFiled: April 15, 2010Publication date: August 5, 2010Applicant: PALO ALTO RESEARCH CENTER INCORPORATEDInventors: Huangpin Ben Hsieh, Jeng Ping Lu
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Patent number: 7749748Abstract: A compact sensor for detecting the presence of biological or chemical species includes a microdisk laser and a wavelength shift detector. The microdisk laser is coated with a biological or chemical recognition element, which binds preferentially with a target analyte. Because the recognition element and the target analyte adhere to the sidewall surface of the microdisk laser, they increase the effective diameter of the laser, which shifts the output wavelength by a detectable amount. The presence of a wavelength shift indicates the presence of the target analyte, and the magnitude of the wavelength shift corresponds to the mass load of the target analyte on the sidewall surface of the microdisk laser.Type: GrantFiled: May 9, 2008Date of Patent: July 6, 2010Assignee: Palo Alto Research Center, Inc.Inventors: Peter Kiesel, Noble M Johnson, Meng H Lean, H. Ben Hsieh, Michael A Kneissl
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Patent number: 7727471Abstract: Disclosed is a system using a large area flat panel imager which is specifically adapted for rare cell detection methods. The system generally includes an imager having a sample receiving surface which can provide a digital or electronic image of a sample deposited on the surface. The system also includes a selectively positionable microscope and/or camera which are used to obtain high resolution images of the deposited samples. An electronic controller can also be used in conjunction with the imager, microscope, and/or camera to selectively position at least one of those components to focus on desired regions of the deposited sample. The noted system is particularly adapted for use with chemiluminescence or other tagging technologies.Type: GrantFiled: September 9, 2004Date of Patent: June 1, 2010Assignee: Palo Alto Research Center IncorporatedInventors: Huangpin Ben Hsieh, JengPeng Lu
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Patent number: 7681738Abstract: Various traveling wave grid configurations are disclosed. The grids and systems are well suited for transporting, separating, and classifying small particles dispersed in liquid or gaseous media. Also disclosed are various separation strategies and purification cells utilizing such traveling wave arrays and strategies.Type: GrantFiled: September 12, 2005Date of Patent: March 23, 2010Assignee: Palo Alto Research Center IncorporatedInventors: Meng H. Lean, Jeng Ping Lu, Scott J. Limb, Jürgen H. Daniel, Armin R. Völkel, Huangpin Ben Hsieh, Scott E. Solberg, Bryan T. Preas
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Patent number: 7538192Abstract: A technique for forming conjugates of proteins and oligonucleotides is disclosed in which conjugation is performed while the oligonucleotide is attached to support media such as glass beads. The conjugated product may then be readily removed from the support media. Also disclosed are the conjugated products formed by this technique. The present invention is particularly directed to conjugates of albumin proteins and specifically to bovine serum albumin (BSA).Type: GrantFiled: July 1, 2005Date of Patent: May 26, 2009Assignee: Palo Alto Research Center IncorporatedInventor: Huangpin Ben Hsieh
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Patent number: 7534336Abstract: An apparatus for extracting and concentrating bioagents within a continuously flowing fluid medium includes a flow channel fluid inlet, in which bioagents are concentrated from three dimensions to a two-dimensional transport layer in a preconcentration area. Traveling wave grids cause the preconcentrated bioagents to migrate to one side of the flow channel and then to an extraction port. Each of the traveling wave grids includes a substrate, a collection of closely spaced and parallel electrically conductive electrodes extending across said substrate, and a collection of buses providing electrical communication with the collection of conductive electrodes. A voltage controller provides a multiphase electrical signal to the collection of buses and electrodes of the traveling wave grids. Fluid exits through an outlet port.Type: GrantFiled: May 4, 2004Date of Patent: May 19, 2009Assignee: Palo Alto Research Center IncorporatedInventors: Armin R. Volkel, Meng H. Lean, H Ben Hsieh, Jurgen H Daniel
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Patent number: 7491307Abstract: A portable apparatus for extracting and concentrating bioagents within a fluid medium includes a container with sample solution inlet port and traveling wave grids patterned on surfaces of the container. The traveling wave grids cause bioagents to migrate to a specified surface within the container and then to an extraction port. The traveling wave grids include a substrate, across which extend a collection of closely spaced and parallel electrically conductive electrodes, and a collection of buses providing electrical communication with the collection of conductive electrodes. A voltage controller provides a multiphase electrical signal to the collection of buses and electrodes of the traveling wave grids.Type: GrantFiled: May 4, 2004Date of Patent: February 17, 2009Assignee: Palo Alto Research Center IncorporatedInventors: H Ben Hsieh, Meng H. Lean, Bryan T. Preas, Armin R. Volkel
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Publication number: 20080204709Abstract: A compact sensor for detecting the presence of biological or chemical species includes a microdisk laser and a wavelength shift detector. The microdisk laser is coated with a biological or chemical recognition element, which binds preferentially with a target analyte. Because the recognition element and the target analyte adhere to the sidewall surface of the microdisk laser, they increase the effective diameter of the laser, which shifts the output wavelength by a detectable amount. The presence of a wavelength shift indicates the presence of the target analyte, and the magnitude of the wavelength shift corresponds to the mass load of the target analyte on the sidewall surface of the microdisk laser.Type: ApplicationFiled: May 9, 2008Publication date: August 28, 2008Applicant: PALO ALTO RESEARCH CENTER INCORPORATEDInventors: Peter KIESEL, Noble M. Johnson, Meng H. Lean, H. Ben Hsieh, Michael A. Kneissl
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Patent number: 7387892Abstract: A compact sensor for detecting the presence of biological or chemical species includes a microdisk laser and a wavelength shift detector. The microdisk laser is coated with a biological or chemical recognition element, which binds preferentially with a target analyte. Because the recognition element and the target analyte adhere to the sidewall surface of the microdisk laser, they increase the effective diameter of the laser, which shifts the output wavelength by a detectable amount. The presence of a wavelength shift indicates the presence of the target analyte, and the magnitude of the wavelength shift corresponds to the mass load of the target analyte on the sidewall surface of the microdisk laser.Type: GrantFiled: September 1, 2004Date of Patent: June 17, 2008Assignee: Palo Alto Research Center IncorporatedInventors: Peter Kiesel, Noble M. Johnson, Meng H. Lean, H. Ben Hsieh, Michael A. Kneissl
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Patent number: 7309410Abstract: Various traveling wave grids and related systems are disclosed that are particularly beneficial for the separation, transport, and focusing of biomolecules or other charged species. An implementation of a vertically integrated traveling wave module is described which allows for scalability to arbitrary gel dimensions through tiling. In addition, several unique traveling wave algorithms are also described which when used in conjunction with the traveling wave grids, impart selective motion to biomolecules or other charged species.Type: GrantFiled: December 3, 2003Date of Patent: December 18, 2007Assignee: Palo Alto Research Center IncorporatedInventors: Meng H. Lean, Jeng Ping Lu, Jackson Ho, Chinwen Shih, Armin R. Völkel, Huangpin Ben Hsieh, Jurgen Daniel
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Patent number: 7282129Abstract: An electrophoretic cell configuration and related method are disclosed that employ oppositely directed traveling electrical waves. The waves travel across the cell and samples undergoing separation. Various strategies are used to selectively direct the movement and arrangement of the samples and resulting sample patterns.Type: GrantFiled: June 12, 2003Date of Patent: October 16, 2007Assignee: Palo Alto Research Center IncorporatedInventors: Meng H. Lean, Huangpin Ben Hsieh, John S. Fitch, Armin R. Völkel, Bryan Preas, Scott Elrod, Richard H. Bruce, Eric Peeters, Frank Torres, Michael Chabinyc
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Patent number: 7268868Abstract: An improved method of analyzing target analytes in a sample is described. The method is based on anti-resonant guided optical waveguides which enables a strongly improved light-target interaction since the light can be guided within the target-containing medium. The light-target interaction can be monitored by many different means to determine characteristics of the target analyte. The anti-resonant waveguide concept is suitable for a large variety of characterization methods and combinations of them, since it is relatively unaffected by changes to both wavelength and film thickness.Type: GrantFiled: October 29, 2004Date of Patent: September 11, 2007Assignee: Palo Alto Research Center IncorporatedInventors: Peter Kiesel, Oliver H. Wolst, Michael A. Kneissl, H Ben Hsieh
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Patent number: 7248361Abstract: A sample detection system including an anti-resonant waveguide, including a sample having a first index of refraction, a top layer and a substrate surrounding the sample, where the top layer has a second index of refraction, and the substrate has a third index of refraction. The second index of refraction, and the third index of refraction are both greater than the first index of refraction. A detection device of the system includes a low power light source used to direct light into the sample and generate an anti-resonant optical mode in the sample, and an analyzing system to detect the interaction of the light propagating in the sample.Type: GrantFiled: December 22, 2005Date of Patent: July 24, 2007Assignee: Palo Alto Research Center IncorporatedInventors: Peter Kiesel, Oliver Wolst, Michael Kneissl, Huangpin Ben Hsieh, Oliver Schmidt