Patents by Inventor Ben Ross-Johnsrud
Ben Ross-Johnsrud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10975368Abstract: An acoustophoresis device includes an acoustic chamber with a piezoelectric element located within its volume. The piezoelectric element vibrates and generates acoustic standing waves from both sides, so that particles can be separated from fluid passing through the acoustic chamber. This permits the element to be cooled more efficiently, reducing transient heat loads in the fluid traveling through the device.Type: GrantFiled: August 8, 2017Date of Patent: April 13, 2021Assignee: FloDesign Sonics, Inc.Inventors: Bart Lipkens, Brian McCarthy, Ben Ross-Johnsrud, Jason Barnes, Dane Mealey, Thomas J. Kennedy, III
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Patent number: 10814253Abstract: Devices for separating a host fluid from a second fluid or particulate are disclosed. The devices include an acoustic chamber, a fluid outlet at a top end of the acoustic chamber, a concentrate outlet at a bottom end of the acoustic chamber, and an inlet on a first side end of the acoustic chamber. An ultrasonic transducer and reflector create a multi-dimensional acoustic standing wave in the acoustic chamber that traps and separates particulates (e.g. cells) from a host fluid. The host fluid is collected via the fluid outlet, and the particulates are collected via the concentrate outlet. The device is a large-scale device that is able to process liters/hour, and has a large interior volume.Type: GrantFiled: August 29, 2017Date of Patent: October 27, 2020Assignee: FloDesign Sonics, Inc.Inventors: Bart Lipkens, Walter M. Presz, Jr., Jeffrey King, Jason Barnes, Dane Mealey, Brian McCarthy, Ben Ross-Johnsrud, Kedar Chitale
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Patent number: 10550382Abstract: Devices for separating materials from a host fluid are disclosed. The devices include a flow chamber, an ultrasonic transducer, and a reflector. The ultrasonic transducer and reflector create an angled acoustic standing wave oriented at an angle relative to the direction of mean flow through the flow chamber. The angled acoustic standing wave results in an acoustic radiation force having an axial force component that deflects the materials, so that the materials and the host fluid can thus be separated. The angled acoustic standing wave can be oriented at an angle of about 20° to about 70° relative to the direction of mean flow through the flow chamber to deflect, collect, differentiate, or fractionate the materials from the fluid flowing through the device at flow rates of about 400 mL/min up to about 700 mL/min.Type: GrantFiled: June 5, 2017Date of Patent: February 4, 2020Assignee: FloDesign Sonics, Inc.Inventors: Bart Lipkens, Walter M. Presz, Jr., Kedar Chitale, Thomas J. Kennedy, III, Ben Ross-Johnsrud
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Publication number: 20180015392Abstract: Devices for separating a host fluid from a second fluid or particulate are disclosed. The devices include an acoustic chamber, a fluid outlet at a top end of the acoustic chamber, a concentrate outlet at a bottom end of the acoustic chamber, and an inlet on a first side end of the acoustic chamber. An ultrasonic transducer and reflector create a multi-dimensional acoustic standing wave in the acoustic chamber that traps and separates particulates (e.g. cells) from a host fluid. The host fluid is collected via the fluid outlet, and the particulates are collected via the concentrate outlet. The device is a large-scale device that is able to process liters/hour, and has a large interior volume.Type: ApplicationFiled: August 29, 2017Publication date: January 18, 2018Inventors: Bart Lipkens, Walter M. Presz, JR., Jeffrey King, Jason Barnes, Dane Mealey, Brian McCarthy, Ben Ross-Johnsrud, Kedar Chitale
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Publication number: 20170369865Abstract: An acoustophoresis device includes an acoustic chamber with a piezoelectric element located within its volume. The piezoelectric element vibrates and generates acoustic standing waves from both sides, so that particles can be separated from fluid passing through the acoustic chamber. This permits the element to be cooled more efficiently, reducing transient heat loads in the fluid traveling through the device.Type: ApplicationFiled: August 8, 2017Publication date: December 28, 2017Inventors: Bart Lipkens, Brian McCarthy, Ben Ross-Johnsrud, Jason Barnes, Dane Mealey, Thomas J. Kennedy, III
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Patent number: 9827511Abstract: An acoustophoresis device which includes a substantially vertical flow path of the fluid mixture in order to improve separation of particles/secondary fluid from a primary fluid is disclosed. The vertical flow path reduces velocity non-uniformities in the acoustic chamber resulting from gravity forces. The device includes an acoustic chamber in which multidimensional acoustic standing waves are generated. The fluid can be introduced into the acoustic chamber using a dump diffuser in which a plurality of inlets enter near the bottom of the acoustic chamber such that flow symmetry reduces both, gravity driven flow non-uniformities, and any flow interference effects between inlet mixture flow into the acoustic chamber and the continuous gravity driven particle cluster drop out.Type: GrantFiled: July 2, 2015Date of Patent: November 28, 2017Assignee: FLODESIGN SONICS, INC.Inventors: Bart Lipkens, Brian McCarthy, Jason Barnes, Dane Mealey, Ben Ross-Johnsrud, Walter M. Presz, Jr., Kedar Chitale
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Publication number: 20170267992Abstract: Devices for separating materials from a host fluid are disclosed. The devices include a flow chamber, an ultrasonic transducer, and a reflector. The ultrasonic transducer and reflector create an angled acoustic standing wave oriented at an angle relative to the direction of mean flow through the flow chamber. The angled acoustic standing wave results in an acoustic radiation force having an axial force component that deflects the materials, so that the materials and the host fluid can thus be separated. The angled acoustic standing wave can be oriented at an angle of about 20° to about 70° relative to the direction of mean flow through the flow chamber to deflect, collect, differentiate, or fractionate the materials from the fluid flowing through the device at flow rates of about 400 mL/min up to about 700 mL/min.Type: ApplicationFiled: June 5, 2017Publication date: September 21, 2017Inventors: Bart Lipkens, Walter M. Presz, JR., Kedar Chitale, Thomas J. Kennedy, III, Ben Ross-Johnsrud
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Publication number: 20170260493Abstract: Methods, systems, and apparatus for acoustic separation of cellular supporting materials such as microcarriers or microbubbles from cell culture are provided.Type: ApplicationFiled: May 26, 2017Publication date: September 14, 2017Inventors: Bart Lipkens, Rudolf Gilmanshin, Ben Ross-Johnsrud, Kedar Chitale
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Patent number: 9744483Abstract: Devices for separating a host fluid from a second fluid or particulate are disclosed. The devices include an acoustic chamber, a fluid outlet at a top end of the acoustic chamber, a concentrate outlet at a bottom end of the acoustic chamber, and an inlet on a first side end of the acoustic chamber. An ultrasonic transducer and reflector create a multi-dimensional acoustic standing wave in the acoustic chamber that traps and separates particulates (e.g. cells) from a host fluid. The host fluid is collected via the fluid outlet, and the particulates are collected via the concentrate outlet. The device is a large-scale device that is able to process liters/hour, and has a large interior volume.Type: GrantFiled: August 26, 2016Date of Patent: August 29, 2017Assignee: FloDesign Sonics, Inc.Inventors: Bart Lipkens, Walter M. Presz, Jr., Jeffrey King, Jason Barnes, Dane Mealey, Brian McCarthy, Ben Ross-Johnsrud, Kedar Chitale
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Patent number: 9725710Abstract: An acoustophoresis device includes an acoustic chamber with a piezoelectric element located within its volume. The piezoelectric element vibrates and generates acoustic standing waves from both sides, so that particles can be separated from fluid passing through the acoustic chamber. This permits the element to be cooled more efficiently, reducing transient heat loads in the fluid traveling through the device.Type: GrantFiled: January 8, 2015Date of Patent: August 8, 2017Assignee: FloDesign Sonics, Inc.Inventors: Bart Lipkens, Brian McCarthy, Ben Ross-Johnsrud, Jason Barnes, Dane Mealey, Thomas J. Kennedy, III
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Patent number: 9670477Abstract: Devices for separating materials from a host fluid are disclosed. The devices include a flow chamber, an ultrasonic transducer, and a reflector. The ultrasonic transducer and reflector create an angled acoustic standing wave oriented at an angle relative to the direction of mean flow through the flow chamber. The angled acoustic standing wave results in an acoustic radiation force having an axial force component that deflects the materials, so that the materials and the host fluid can thus be separated. The angled acoustic standing wave can be oriented at an angle of about 20° to about 70° relative to the direction of mean flow through the flow chamber to deflect, collect, differentiate, or fractionate the materials from the fluid flowing through the device at flow rates of about 400 mL/min up to about 700 mL/min.Type: GrantFiled: April 29, 2016Date of Patent: June 6, 2017Assignee: FloDesign Sonics, Inc.Inventors: Bart Lipkens, Walter M. Presz, Kedar Chitale, Thomas J. Kennedy, III, Ben Ross-Johnsrud
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Patent number: 9663756Abstract: Methods, systems, and apparatus for acoustic separation of cellular supporting materials such as microcarriers or microbubbles from cell culture are provided.Type: GrantFiled: February 25, 2016Date of Patent: May 30, 2017Assignee: FloDesign Sonics, Inc.Inventors: Bart Lipkens, Rudolf Gilmanshin, Ben Ross-Johnsrud, Kedar Chitale
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Patent number: 9623348Abstract: An apparatus includes a flow chamber having at least one inlet and at least one outlet. At least one ultrasonic transducer is located on a wall of the flow chamber, which operates to create a multi-dimensional acoustic standing wave in the flow chamber. A reflector is located on the wall on the opposite side of the flow chamber from the at least one ultrasonic transducer. The reflector is formed from a thin structure that provides a pressure release boundary, such as a plastic film/air interface.Type: GrantFiled: April 3, 2015Date of Patent: April 18, 2017Assignee: FloDesign Sonics, Inc.Inventors: Brian McCarthy, Ben Ross-Johnsrud, Bart Lipkens
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Publication number: 20170081629Abstract: An acoustophoresis device made up of modular components is disclosed. Several modules are disclosed herein, including ultrasonic transducer modules, input/output modules, collection well modules, and various connector modules. These permit different systems to be constructed that have appropriate fluid dynamics for separation of particles, such as biological cells, from a fluid.Type: ApplicationFiled: December 6, 2016Publication date: March 23, 2017Inventors: Bart Lipkens, Jason Barnes, Dane Mealey, Walter M. Presz, JR., Stanley Kowalski, III, Louis Masi, Thomas J. Kennedy, III, Brian McCarthy, Ben Ross-Johnsrud
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Publication number: 20160361670Abstract: Devices for separating a host fluid from a second fluid or particulate are disclosed. The devices include an acoustic chamber, a fluid outlet at a top end of the acoustic chamber, a concentrate outlet at a bottom end of the acoustic chamber, and an inlet on a first side end of the acoustic chamber. An ultrasonic transducer and reflector create a multi-dimensional acoustic standing wave in the acoustic chamber that traps and separates particulates (e.g. cells) from a host fluid. The host fluid is collected via the fluid outlet, and the particulates are collected via the concentrate outlet. The device is a large-scale device that is able to process liters/hour, and has a large interior volume.Type: ApplicationFiled: August 26, 2016Publication date: December 15, 2016Inventors: Bart Lipkens, Walter M. Presz, JR., Jeffrey King, Jason Barnes, Dane Mealey, Brian McCarthy, Ben Ross-Johnsrud, Kedar Chitale
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Patent number: 9512395Abstract: An acoustophoresis device made up of modular components is disclosed. Several modules are disclosed herein, including ultrasonic transducer modules, input/output modules, collection well modules, and various connector modules. These permit different systems to be constructed that have appropriate fluid dynamics for separation of particles, such as biological cells, from a fluid.Type: GrantFiled: November 5, 2014Date of Patent: December 6, 2016Assignee: FloDesign Sonics, Inc.Inventors: Bart Lipkens, Jason Barnes, Dane Mealey, Walter M. Presz, Jr., Stanley Kowalski, III, Louis Masi, Thomas J. Kennedy, III, Brian McCarthy, Ben Ross-Johnsrud
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Publication number: 20160002070Abstract: An acoustophoresis device which includes a substantially vertical flow path of the fluid mixture in order to improve separation of particles/secondary fluid from a primary fluid is disclosed. The vertical flow path reduces velocity non-uniformities in the acoustic chamber resulting from gravity forces. The device includes an acoustic chamber in which multidimensional acoustic standing waves are generated. The fluid can be introduced into the acoustic chamber using a dump diffuser in which a plurality of inlets enter near the bottom of the acoustic chamber such that flow symmetry reduces both, gravity driven flow non-uniformities, and any flow interference effects between inlet mixture flow into the acoustic chamber and the continuous gravity driven particle cluster drop out.Type: ApplicationFiled: July 2, 2015Publication date: January 7, 2016Inventors: Bart Lipkens, Brian McCarthy, Jason Barnes, Dane Mealey, Ben Ross-Johnsrud, Walter M. Presz, JR., Kedar Chitale
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Publication number: 20150209695Abstract: An apparatus includes a flow chamber having at least one inlet and at least one outlet. At least one ultrasonic transducer is located on a wall of the flow chamber, which operates to create a multi-dimensional acoustic standing wave in the flow chamber. A reflector is located on the wall on the opposite side of the flow chamber from the at least one ultrasonic transducer. The reflector is formed from a thin structure that provides a pressure release boundary, such as a plastic film/air interface.Type: ApplicationFiled: April 3, 2015Publication date: July 30, 2015Inventors: Brian McCarthy, Ben Ross-Johnsrud, Bart Lipkens
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Publication number: 20150191716Abstract: An acoustophoresis device includes an acoustic chamber with a piezoelectric element located within its volume. The piezoelectric element vibrates and generates acoustic standing waves from both sides, so that particles can be separated from fluid passing through the acoustic chamber. This permits the element to be cooled more efficiently, reducing transient heat loads in the fluid traveling through the device.Type: ApplicationFiled: January 8, 2015Publication date: July 9, 2015Inventors: Bart Lipkens, Brian McCarthy, Ben Ross-Johnsrud, Jason Barnes, Dane Mealey, Thomas J. Kennedy, III