Patents by Inventor Benjamin Andrew PORTNEY

Benjamin Andrew PORTNEY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF
    Publication number: 20230332145
    Abstract: The present disclosure relates generally to compositions of synthetic bifunctional molecules comprising a first domain that specifically binds to a target ribonucleic acid sequence and a second domain that specifically binds to a target protein, and uses thereof.
    Type: Application
    Filed: March 24, 2021
    Publication date: October 19, 2023
    Applicant: Flagship Pioneering, Inc.
    Inventors: Nathan Wilson STEBBINS, Benjamin Andrew PORTNEY, Eric Bruno VALEUR, Chih-Chi Yuan, Mitchell Guttman
  • DNA COMPOSITIONS AND RELATED METHODS
    Publication number: 20230255999
    Abstract: The disclosure provides, for example, single stranded, covalently closed DNA that does not form a double stranded structure longer than 100 base pairs. The ssDNA may encode an effector sequence, for instance a therapeutic protein. The ssDNA may comprise a nuclear targeting sequence (NTS). In some embodiments, the ssDNA shows decreased activation of the innate immune system compared to an otherwise similar dsDNA.
    Type: Application
    Filed: November 11, 2022
    Publication date: August 17, 2023
    Inventors: Alexandra Rachael Sneider, Jacob Rosenblum Rubens, Narahari Subbanna Pujar, Molly Krisann Gibson, Benjamin Andrew Portney, Geoffrey A. Von Maltzahn, Camilo Ayala Breton
  • BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF
    Publication number: 20230167450
    Abstract: The present disclosure relates generally to compositions of synthetic bifunctional molecules comprising a first domain that specifically binds to a target ribonucleic acid and a second domain that specifically binds to a target protein, and uses thereof.
    Type: Application
    Filed: April 21, 2021
    Publication date: June 1, 2023
    Applicant: Flagship Pioneering, Inc.
    Inventors: Nathan Wilson STEBBINS, Benjamin Andrew PORTNEY, Eric Bruno VALEUR, Jacob Rosenblum RUBENS, Kaveh DANESHVAR, Alexandra Rachael SNEIDER, Mitchell GUTTMAN
  • BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF
    Publication number: 20230158156
    Abstract: The present disclosure relates generally to compositions of synthetic bifunctional molecules comprising a first domain that specifically binds to a target ribonucleic acid and a second domain that specifically binds to a target polypeptide, and uses thereof.
    Type: Application
    Filed: April 21, 2021
    Publication date: May 25, 2023
    Applicant: Flagship Pioneering, Inc.
    Inventors: Nathan Wilson STEBBINS, Benjamin Andrew PORTNEY, Eric Bruno VALEUR, Jacob Rosenblum RUBENS, Kaveh DANESHVAR, Alexandra Rachael SNEIDER