Patents by Inventor Benjamin Blass

Benjamin Blass has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL FUNCTIONALIZED LACTONES AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE
    Publication number: 20230025932
    Abstract: Described herein are new, selective modulators of the 5-HT7receptor. These selective compounds can be useful for the treatment of CNS and non-CNS indications.
    Type: Application
    Filed: November 12, 2020
    Publication date: January 26, 2023
    Inventors: Daniel J. Canney, Benjamin Blass Blass, Kevin M. Blattner, Douglas A. Pippin
  • Anti-PCSK9 compounds and methods for the treatment and/or prevention of cardiovascular diseases
    Patent number: 10131637
    Abstract: Disclosed are compounds of the class of 2-phenylacetamides that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), and methods of using these modulators to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: November 20, 2018
    Assignees: Shifa Biomedical Corporation, Temple University—Of The Commonwealth System of Higher Education
    Inventors: Sherin Salaheldin Abdel-Meguid, Magid Abou-Gharbia, Benjamin Blass, Wayne Childers, Nabil Elshourbagy, Victor Ghidu, Rogelio Martinez, Harold Meyers, Shaker A. Mousa
  • ANTI-PCSK9 COMPOUNDS AND METHODS FOR THE TREATMENT AND/OR PREVENTION OF CARDIOVASCULAR DISEASES
    Publication number: 20180079730
    Abstract: Disclosed are compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), and methods of using these modulators to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia.
    Type: Application
    Filed: December 1, 2017
    Publication date: March 22, 2018
    Inventors: Sherin Salaheldin Abdel-Meguid, Magid Abou-Gharbia, Benjamin Blass, Wayne Childers, Nabil Elshourbagy, Victor Ghidu, Rogelio Martinez, Harold Meyers, Shaker A. Mousa
  • ANTI-PCSK9 COMPOUNDS AND METHODS FOR THE TREATMENT AND/OR PREVENTION OF CARDIOVASCULAR DISEASES
    Publication number: 20150376139
    Abstract: Disclosed are compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), and methods of using these modulators to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia.
    Type: Application
    Filed: March 11, 2014
    Publication date: December 31, 2015
    Inventors: Sherin Salaheldin Abdel-Meguid, Magid Abou-Gharbia, Benjamin Blass, Wayne Childers, Nabil Elshourbagy, Victor Ghidu, Rogelio Martinez, Harold Meyers, Shaker A. Mousa
  • KV1.5 POTASSIUM CHANNEL INHIBITORS
    Publication number: 20070299120
    Abstract: The present invention relates to 1-N-amino-2-imidazolidinones and derivatives thereof which are effective as Kv1.5 potassium channel inhibitors providing atrial-selective antiarrhythmic agents. The present invention further relates to compositions comprising said Kv1.5 potassium channel inhibitors, and to methods for treating cardiac arrhythmia.
    Type: Application
    Filed: June 19, 2007
    Publication date: December 27, 2007
    Applicant: Wyeth
    Inventors: John Janusz, Stephen Hodson, Gregory Bosch, Ronald White, Benjamin Blass, Christopher Jackson, Neil Fairweather
  • KV1.5 POTASSIUM CHANNEL INHIBITORS
    Publication number: 20070299072
    Abstract: The present invention relates to 4-oxo-1,3,8-triaza-spiro[4.5]decanes which are useful as Kv1.5 potassium channel inhibitors providing atrial-selective antiarrhythmic activity. The present invention further relates to compositions and methods for treating atrial-selective antiarrhythmia.
    Type: Application
    Filed: June 19, 2007
    Publication date: December 27, 2007
    Applicant: Wyeth
    Inventors: John Janusz, Shengde Wu, Neil Fairweather, Wenlin Lee, Benjamin Blass, Andrew Fluxe, Stephen Hodson, James Ridgeway