Patents by Inventor Benjamin D. Pless

Benjamin D. Pless has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulation and analysis of cerebral perfusion in epilepsy and other neurological disorders
    Patent number: 8478419
    Abstract: A system including an implantable neurostimulator device capable of modulating cerebral blood flow to treat epilepsy and other neurological disorders. In one embodiment, the system is capable of modulating cerebral blood flow (also referred to as cerebral perfusion) in response to measurements and other observed conditions. Perfusion may be increased or decreased by systems and methods according to the invention as clinically required.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: July 2, 2013
    Assignee: NeuroPace, Inc.
    Inventors: Benjamin D. Pless, Brett Wingeier
  • Drug eluting lead systems
    Patent number: 8423156
    Abstract: Medical electrical lead systems and related methods are described. The lead systems may be configured to be at least partially implanted in neural tissue of a subject, such as a brain of a subject. Some variations of the lead systems may comprise a lead body, an electrode connected to the lead body, and a bioactive agent. The electrode and/or lead body may comprise a substrate, and the bioactive agent may be supported by the substrate (e.g., by a substantial portion of the area of the substrate). Methods described herein may comprise contacting the substrate of a lead body and/or an electrode of a medical electrical lead system with at least one bioactive agent, where the lead body and the electrode are connected to each other.
    Type: Grant
    Filed: February 9, 2012
    Date of Patent: April 16, 2013
    Assignee: NeuroPace, Inc.
    Inventors: C. Lance Boling, Daniel Chao, Martha J. Morrell, Benjamin D. Pless, Thomas K. Tcheng, Brett M. Wingeier
  • Differential neurostimulation therapy driven by physiological therapy
    Patent number: 8423145
    Abstract: An implantable neurostimulator system adapted to provide therapy for various neurological disorders is capable of varying therapy delivery strategies based on the context, physiological or otherwise, into which the therapy is to be delivered. Responsive and scheduled therapies can be varied depending on various sensor measurements, calculations, inferences, and device states (including elapsed times and times of day) to deliver an appropriate course of therapy under the circumstances.
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: April 16, 2013
    Assignee: NeuroPace, Inc.
    Inventors: Benjamin D. Pless, Thomas K. Tcheng
  • Neurostimulator involving stimulation strategies and process for using it
    Patent number: 8412333
    Abstract: This is a neurostimulator that is configured to treat epilepsy and other neurological disorders using certain stimulation strategies, particularly changing various pulse parameters, during the imposition of a burst of those pulses. The invention includes the processes embodying those stimulation strategies.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: April 2, 2013
    Assignee: NeuroPace, Inc.
    Inventor: Benjamin D Pless
  • Devices and methods for monitoring physiological information relating to sleep with an implantable device
    Patent number: 8369940
    Abstract: Described here are implantable devices and methods for monitoring physiological information relating to sleep. The implantable devices are generally designed to include at least one sensor for sensing physiological information, a processor for processing the physiological information using low computational power to detect a sleep stage, and a battery. The detected sleep stage information may then be used to indicate sleep quality, identify or monitor a medical condition, or guide treatment thereof.
    Type: Grant
    Filed: October 14, 2011
    Date of Patent: February 5, 2013
    Assignee: NeuroPace, Inc.
    Inventors: Felice Sun, Benjamin D Pless, Barbara Gibb
  • Modulation and analysis of cerebral perfusion in epilepsy and other neurological disorders
    Patent number: 8353837
    Abstract: A system including an implantable neurostimulator device capable of modulating cerebral blood flow to treat epilepsy and other neurological disorders. In one embodiment, the system is capable of modulating cerebral blood flow (also referred to as cerebral perfusion) in response to measurements and other observed conditions. Perfusion may be increased or decreased by systems and methods according to the invention as clinically required.
    Type: Grant
    Filed: February 4, 2010
    Date of Patent: January 15, 2013
    Assignee: NeuroPace, Inc.
    Inventors: Michael Sasha John, Benjamin D. Pless, Brett Wingeier
  • Neurostimulator involving stimulation strategies and process for using it
    Patent number: 8326417
    Abstract: This is a neurostimulator that is configured to treat epilepsy and other neurological disorders using certain stimulation strategies, particularly changing various pulse parameters, during the imposition of a burst of those pulses. The invention includes the processes embodying those stimulation strategies.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: December 4, 2012
    Assignee: NeuroPace, Inc.
    Inventor: Benjamin D Pless
  • DIFFERENTIAL NEUROSTIMULATION THERAPY DRIVEN BY PHYSIOLOGICAL THERAPY
    Publication number: 20120253417
    Abstract: An implantable neurostimulator system adapted to provide therapy for various neurological disorders is capable of varying therapy delivery strategies based on the context, physiological or otherwise, into which the therapy is to be delivered. Responsive and scheduled therapies can be varied depending on various sensor measurements, calculations, inferences, and device states (including elapsed times and times of day) to deliver an appropriate course of therapy under the circumstances.
    Type: Application
    Filed: June 14, 2012
    Publication date: October 4, 2012
    Applicant: NeuroPace Inc.
    Inventors: Benjamin D. Pless, Thomas K. Tcheng
  • DRUG ELUTING LEAD SYSTEMS
    Publication number: 20120232628
    Abstract: Medical electrical lead systems and related methods are described. The lead systems may be configured to be at least partially implanted in neural tissue of a subject, such as a brain of a subject. Some variations of the lead systems may comprise a lead body, an electrode connected to the lead body, and a bioactive agent. The electrode and/or lead body may comprise a substrate, and the bioactive agent may be supported by the substrate (e.g., by a substantial portion of the area of the substrate). Methods described herein may comprise contacting the substrate of a lead body and/or an electrode of a medical electrical lead system with at least one bioactive agent, where the lead body and the electrode are connected to each other.
    Type: Application
    Filed: February 9, 2012
    Publication date: September 13, 2012
    Applicant: NeuroPace, Inc.
    Inventors: C. Lance Boling, Daniel Chao, Martha J. Morrell, Benjamin D. Pless, Thomas K. Tcheng, Brett M. Wingeier
  • Treatment and warning of recurring therapy and other events using an implantable device
    Patent number: 8249712
    Abstract: An implantable neurostimulator system is capable of responsively treating epileptiform activity with electrical stimulation and other therapies and is further configured to detect periods of increased susceptibility to clinical seizures. The event densities of therapy applications (or detections or other events) in time are observed and calculated, and if high enough, measures are taken to warn the patient or provide additional therapy.
    Type: Grant
    Filed: November 10, 2011
    Date of Patent: August 21, 2012
    Assignee: NeuroPace, Inc.
    Inventor: Benjamin D Pless
  • Differential neurostimulation therapy driven by physiological therapy
    Patent number: 8224452
    Abstract: An implantable neurostimulator system adapted to provide therapy for various neurological disorders is capable of varying therapy delivery strategies based on the context, physiological or otherwise, into which the therapy is to be delivered. Responsive and scheduled therapies can be varied depending on various sensor measurements, calculations, inferences, and device states (including elapsed times and times of day) to deliver an appropriate course of therapy under the circumstances.
    Type: Grant
    Filed: May 17, 2011
    Date of Patent: July 17, 2012
    Assignee: NeuroPace Inc.
    Inventors: Benjamin D Pless, Thomas K Tcheng
  • Systems and methods for interacting with an implantable medical device
    Patent number: 8140160
    Abstract: An interactive implantable medical device system includes an implantable medical device and a network-enabled external device capable of bi-directional communication and interaction with the implantable medical device. The external device is programmed to interact with other similarly-enabled devices. The system facilitates improved patient care by eliminating unnecessary geographic limitations on implantable medical device interrogation and programming, and by allowing patients, physicians, and other users to access medical records, history, and information and to receive status and care-related alerts and messages anywhere there is access to a communications network.
    Type: Grant
    Filed: May 16, 2006
    Date of Patent: March 20, 2012
    Assignee: NeuroPace, Inc.
    Inventors: Benjamin D. Pless, David R. Fischell, Barbara Gibb, Lisa Guzzo, Adrian R. M. Upton
  • Functional ferrule
    Patent number: 8140152
    Abstract: Described here are intracranial ferrules, systems, and methods for sensing and stimulating neural tissues. The ferrules are generally designed to include a holding area for retaining an implantable device. In some variations, the ferrule itself may perform the sensing and stimulating functions. In other variations, the ferrule may function to sense data from neural tissues and the implantable device may function to stimulate neural tissues. In yet other variations, the ferrule may function to stimulate, and the implantable device may function to sense data from, the neural tissues. The sensing and stimulating functions may be used to detect and/or treat various neurological conditions.
    Type: Grant
    Filed: May 5, 2010
    Date of Patent: March 20, 2012
    Assignee: NeuroPace, Inc.
    Inventors: Michael S. John, Brett Wingeier, Thomas K. Tcheng, Benjamin D. Pless
  • Treatment and warning of recurring therapy and other events using an implantable device
    Publication number: 20120059430
    Abstract: An implantable neurostimulator system is capable of responsively treating epileptiform activity with electrical stimulation and other therapies and is further configured to detect periods of increased susceptibility to clinical seizures. The event densities of therapy applications (or detections or other events) in time are observed and calculated, and if high enough, measures are taken to warn the patient or provide additional therapy.
    Type: Application
    Filed: November 10, 2011
    Publication date: March 8, 2012
    Applicant: NEUROPACE, INC.
    Inventor: Benjamin D. Pless
  • Devices and methods for monitoring physiological information relating to sleep with an implantable device
    Publication number: 20120035431
    Abstract: Described here are implantable devices and methods for monitoring physiological information relating to sleep. The implantable devices are generally designed to include at least one sensor for sensing physiological information, a processor for processing the physiological information using low computational power to detect a sleep stage, and a battery. The detected sleep stage information may then be used to indicate sleep quality, identify or monitor a medical condition, or guide treatment thereof.
    Type: Application
    Filed: October 14, 2011
    Publication date: February 9, 2012
    Applicant: NEUROPACE, INC.
    Inventors: Felice Sun, Benjamin D Pless, Barbara Gibb
  • Treatment and warning of recurring therapy and other events using an implantable device
    Patent number: 8073545
    Abstract: An implantable neurostimulator system is capable of responsively treating epileptiform activity with electrical stimulation and other therapies and is further configured to detect periods of increased susceptibility to clinical seizures. The event densities of therapy applications (or detections or other events) in time are observed and calculated, and if high enough, measures are taken to warn the patient or provide additional therapy.
    Type: Grant
    Filed: July 21, 2006
    Date of Patent: December 6, 2011
    Assignee: NeuroPace, Inc.
    Inventor: Benjamin D. Pless
  • Neurostimulator involving stimulation strategies and process for using it
    Patent number: 8073544
    Abstract: This is a neurostimulator that is configured to treat epilepsy and other neurological disorders using certain stimulation strategies, particularly changing various pulse parameters, during the imposition of a burst of those pulses. The invention includes the processes embodying those stimulation strategies.
    Type: Grant
    Filed: May 31, 2005
    Date of Patent: December 6, 2011
    Assignee: NeuroPace, Inc.
    Inventor: Benjamin D. Pless
  • Devices and methods for monitoring physiological information relating to sleep with an implantable device
    Patent number: 8068904
    Abstract: Described here are implantable devices and methods for monitoring physiological information relating to sleep. The implantable devices are generally designed to include at least one sensor for sensing physiological information, a processor for processing the physiological information using low computational power to detect a sleep stage, and a battery. The detected sleep stage information may then be used to indicate sleep quality, identify or monitor a medical condition, or guide treatment thereof.
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: November 29, 2011
    Assignee: NeuroPace, Inc.
    Inventors: Felice Sun, Benjamin D Pless, Barbara Gibb
  • Differential Neurostimulation Therapy Driven By Physiological Therapy
    Publication number: 20110218591
    Abstract: An implantable neurostimulator system adapted to provide therapy for various neurological disorders is capable of varying therapy delivery strategies based on the context, physiological or otherwise, into which the therapy is to be delivered. Responsive and scheduled therapies can be varied depending on various sensor measurements, calculations, inferences, and device states (including elapsed times and times of day) to deliver an appropriate course of therapy under the circumstances.
    Type: Application
    Filed: May 17, 2011
    Publication date: September 8, 2011
    Applicant: NEUROPACE, INC.
    Inventors: Benjamin D. Pless, Thomas K. Tcheng
  • NEUROSTIMULATOR INVOLVING STIMULATION STRATEGIES AND PROCESS FOR USING IT
    Publication number: 20110213442
    Abstract: This is a neurostimulator that is configured to treat epilepsy and other neurological disorders using certain stimulation strategies, particularly changing various pulse parameters, during the imposition of a burst of those pulses. The invention includes the processes embodying those stimulation strategies.
    Type: Application
    Filed: May 12, 2011
    Publication date: September 1, 2011
    Applicant: NEUROPACE, INC.
    Inventor: Benjamin D. Pless