Abstract: Several embodiments of the present invention are generally directed to medical visualization systems that comprise combinations of disposable and reusable components, such as catheters, functional handles, hubs, optical devices, etc. Other embodiments of the present invention are generally directed to features and aspects of an in-vivo visualization system that comprises an endoscope having a working channel through which a catheter having viewing capabilities is routed. The catheter may obtain viewing capabilities by being constructed as a vision catheter or by having a fiberscope or other viewing device selectively routed through one of its channels. The catheter is preferably of the steerable type so that the distal end of the catheter may be steered from its proximal end as it is advanced with the body. A suitable use for the in-vivo visualization system includes but is not limited to diagnosis and/or treatment of the duodenum, and particularly the biliary tree.

Abstract: The present invention is directed to features and aspects of an in-vivo visualization system that comprises a catheter having an access port leading to an interior lumen through which an image transmission member is routed, and an endoscope having an access port leading to an interior lumen through which the catheter is routed. The catheter and endoscope are connected by an endoscope attachment device such that a handle of the catheter is mounted distal of the endoscope access port and the catheter access port is distal to the mounted position.

Abstract: A device includes a clip including first and second arms distal ends of which are biased apart and a core member including first and second portions connected to one another via a frangible link. The first portion includes a first protrusion for engaging a cut-out in the first arm. The frangible link is fractured when subjected to a load of at least a predetermined level deploying the clip. The device also includes a capsule slidably housing the core member and a proximal portion of the clip.

Abstract: A tissue clipping apparatus comprises a clip including a proximal end received within a capsule. The clip includes a clip locking member biased to engage a first locking structure of the capsule to lock the clip in the capsule in a closed configuration. The apparatus also comprises a tension member releasably coupling the clip to a proximal end of the device which, during use, remains accessible to a user. The tension member is coupled to the clip by a joint designed to release when subject to a predetermined load to separate the clip from the device, release of the joint releasing the locking member to engage the first locking structure.

Abstract: The proximal actuator is operable with various medical devices which have one tube or wire axially movable with respect to another tube or wire (e.g., a guide wire operable within an actuation sleeve). The actuator includes a deployment handle which is transversely or laterally (not axially) removably attachable. The actuator includes first retaining device (e.g., spring clip grip) removably attachable to the actuation sleeve and second retaining device removably attachable to the wire member. The second retainer moves relative to the first retainer such that the sleeve slides over the wire thereby moving a medical device at the distal end of the system. The handle may have a grip and a sleeve defining an aperture and a sliding member in the sleeve. The slide member is rotatably mounted to one retainer and is threadably mounted to the other retainer such that upon rotation, one moves with respect to the other.

Abstract: An emboli filter for deployment in a body lumen to capture emboli entrained in a fluid flowing through the lumen includes a flexible elongated member sized to be passed through the lumen. A filter media is carried on and substantially surrounding the elongated member. The filter media has a first end secured to the elongated member adjacent the distal end. A second end of the filter media has a periphery movable toward and away from the elongated member. Opposing internal surfaces of the filter media define a volume into which emboli may flow through the second end when the periphery is moved away from the elongated member. The emboli are trapped within the volume when the periphery is moved toward the elongated member. An actuator moves the periphery toward and way from the elongated member. The actuator includes a plurality of elastic loops. The loops are biased to an open loop configuration with the loops urging the periphery away from the elongated member.

Abstract: The proximal actuator is operable with various medical devices which have one tube or wire axially movable with respect to another tube or wire (e.g., a guide wire operable within an actuation sleeve). The actuator includes a deployment handle which is transversely or laterally (not axially) removably attachable. The actuator includes first retaining device (e.g., spring clip grip) removably attachable to the actuation sleeve and second retaining device removably attachable to the wire member. The second retainer moves relative to the first retainer such that the sleeve slides over the wire thereby moving a medical device at the distal end of the system. The handle may have a grip and a sleeve defining an aperture and a sliding member in the sleeve. The slide member is rotatably mounted to one retainer and is threadably mounted to the other retainer such that upon rotation, one moves with respect to the other.

Abstract: An emboli filter for deployment in a body lumen to capture emboli entrained in a fluid flowing through the lumen includes a flexible elongated member sized to be passed through the lumen. A filter media is carried on and substantially surrounding the elongated member. The filter media has a first end secured to the elongated member adjacent the distal end. A second end of the filter media has a periphery movable toward and away from the elongated member. Opposing internal surfaces of the filter media define a volume into which emboli may flow through the second end when the periphery is moved away from the elongated member. The emboli are trapped within the volume when the periphery is moved toward the elongated member. An actuator moves the periphery toward and way from the elongated member. The actuator includes a plurality of elastic loops. The loops are biased to an open loop configuration with the loops urging the periphery away from the elongated member.

Abstract: An emboli filter for deployment in a body lumen to capture emboli entrained in a fluid flowing through the lumen includes a flexible elongated member sized to be passed through the lumen. A filter media is carried on and substantially surrounding the elongated member. The filter media has a first end secured to the elongated member adjacent the distal end. A second end of the filter media has a periphery movable toward and away from the elongated member. Opposing internal surfaces of the filter media define a volume into which emboli may flow through the second end when the periphery is moved away from the elongated member. The emboli are trapped within the volume when the periphery is moved toward the elongated member. An actuator moves the periphery toward and way from the elongated member. The actuator includes a plurality of elastic loops. The loops are biased to an open loop configuration with the loops urging the periphery away from the elongated member.