Abstract: A modular electrode system for therapeutic application of an electric field to a tissue is described. The modular electrode system includes a flexible scaffold that conforms to a variable convex or concave surface such as a resected tissue cavity or other target tissue area and includes one or more surface electrodes in addition to one or more depth electrodes. The modular electrode system includes a control system that communicates with the plurality of electrodes of the flexible scaffold to deliver a stimulating voltage and receive measured voltage values for real-time optimization of the electric field generated within the tissue.

Abstract: A multidimensional tracking system incorporates observed positions of objects tracked within various virtual spaces recorded by a plurality of hierarchical tracking systems based on observable positional relationships between the plurality of hierarchical tracking systems. In one embodiment, the multidimensional tracking system displays and records tracking and manipulation of physical objects over time relative to a virtual space. Further, the multidimensional tracking system can evaluate the accuracy of observed positions of objects as well as mappings that translate each virtual space to one another based on observable positional relationships between tracked objects.

Abstract: Electric field therapy requires the strategic delivery of electrical energy to living tissue. Machine learning in the context of a computer-implemented planning environment can be adopted to enhance planning, monitoring, and modulation of this therapy.

Abstract: An implantable electrode system includes a controller device to treat apply electric field therapy (EFT) to a target structure according to specific anatomical properties of the target structure. The system enables selective association of contacts of the implantable electrode system with one or more target locations of varying tissue types within the body for application and measurement of EFT. The one or more target locations are associated with one or more anticipated tissue parameters that the implantable electrode system uses to apply and update waveform parameters to modulate EFT application from each respective contact to the one or more target locations.

Abstract: Various embodiments of systems and methods for implantable electrode recording of an alternating electric field are disclosed herein. In particular, the system enables interradial distance-based recording of electric field differential resultant from an applied waveform between various locations within an organic structure. The determination of electric field differential between measuring contacts can enable a practitioner to create a mapping of electric field differential throughout an organic structure that can aid in understanding of how structural and material variability throughout the bodily structure affects electric field propagation through the structure.

Abstract: A system provides a computer-implemented rendered visualization of a surgeon's path or “roadmap” to a particular target region during a surgical case are disclosed herein. The system includes an approach library in communication with an operating microscope that includes data related to various surgical approach sequences, or “roadmaps” to various target regions. The approach library can be populated by the system and analyzed for variance and trends, as well as provide direct or indirect instruction and guidance through a display member during a surgical case.

Abstract: Various embodiments of a system and method for the treatment of brain cancer using a subdurally-implanted alternating electric field generation apparatus are disclosed herein.

Abstract: Various embodiments of a system and method for the treatment of brain cancer using a subdurally-implanted alternating electric field generation apparatus are disclosed herein.

Abstract: Various embodiments of a system and method for the treatment of brain cancer using a subdurally -implanted alternating electric field generation apparatus are disclosed herein.

Abstract: Systems and methods are provided for managing depths in stereo images. In one implementation, systems and methods are provided for using a procedural shader and automated rendering to match depths of computer-generated images with that of native stereo images, i.e., images recorded using two cameras for stereo imaging. The system and method may employ a checkerboard and a tri-planar shader, and may further employ a texture reference object to make more convenient and intuitive the depth matching.

Abstract: Systems and methods according to principles disclosed here provide a screen space transform, e.g., implemented as a node, that may be employed to correct alignment issues between left and right eyes of a native stereo plate. The transformations may be in a number of homographic ways, including via translation, rotation, and scaling. By properly aligning stereographic images, subsequent images are properly aligned throughout the animation pipeline. In addition, the viewer experience is significantly improved.

Abstract: Systems and methods according to principles disclosed here provide a screen space transform, e.g., implemented as a node, that may be employed to correct alignment issues between left and right eyes of a native stereo plate. The transformations may be in a number of homographic ways, including via translation, rotation, and scaling. By properly aligning stereographic images, subsequent images are properly aligned throughout the animation pipeline. In addition, the viewer experience is significantly improved.

Abstract: Apparatus and methods are provided to implement a technique for managing stereo images. In one implementation, a computer system corrects misalignments in native stereo plates, i.e., images recorded using two cameras for stereo imaging, using homographic transformations.

Abstract: Systems and methods are provided for managing depths in stereo images. In one implementation, systems and methods are provided for using a procedural shader and automated rendering to match depths of computer-generated images with that of native stereo images, i.e., images recorded using two cameras for stereo imaging. The system and method may employ a checkerboard and a tri-planar shader, and may further employ a texture reference object to make more convenient and intuitive the depth matching.